Azacitidine Related Compounds & Impurities

Azacitidine is a DNA methyltransferase inhibitor that reactivates silenced tumour-suppressor genes through hypomethylation, used for myelodysplastic syndromes and AML.

Simson Pharma Limited along with its subsidiary offices Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) is a trusted manufacturer and supplier of high-quality pharmaceutical reference standards, offering a comprehensive portfolio of Azacitidine reference standards, pharmacopeial and non-pharmacopeial Azacitidine impurities, related compounds, related substances, metabolites, stable isotope-labelled compounds, deuterium labelled compounds and nitrosamine (N-NO) reference standards.

These materials support pharmaceutical research and development, product development, ANDA and DMF submissions, quality control (QC), analytical method development and validation, stability studies, impurity identification, and genotoxic impurity assessment.

Our Azacitidine-related reference standards are thoroughly characterized using advanced analytical techniques and are supplied with comprehensive Certificates of Analysis (COA) and supporting analytical data from our USFDA certified, ISO 17025 and ISO 17034 accredited Lab, to meet global regulatory expectations. EP and USP traceable reference standards can also be provided upon request, subject to availability. Simson is also a provider of EP and USP traceable standards. To ensure consistent quality and reliability, our reference standards are periodically re-tested according to established quality management procedures.

Pharmaceutical Reference Standards / Impurity Standards

Azacitidine
Azacitidine Related Compound B
Azacitidine Related Compound C
Azacetidine USP Related Compound C
Azacitidine Related Compound C Isomer 2
Monoacyl Azacitidine
Azacetidine impurity
Azacitidine Formyl Amidine Analog
Tri Acetyl Azacitidine
Azacitidine Impurity 18
Phenyl(piperidin-4-yl)methanone
Biphenyl-4-yl-phenyl-piperidin-4-yl-methanol
Azacitidine Impurity
Azacetidine Monoacetate
(beta)-1-D-Ribofuranosyl-3-guanylurea
beta-D-Ribofuranose,2,3,5-triacetate
N-(Diaminomethylidene)-N`-[(2S,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]urea(mixture of diastereomers)
beta-L-Ribofuranose1,2,3,5-tetra-O-acetate
1,2,3,5-Tetra-O-acetyl-alpha-D-arabinofuranose
1,2,3,5-Tetra-O-acetyl-alpha-L-arabinofuranose
5-azacytosine dipentose
6-amino-5-azacytosine pentose
6-methyl-5-azacytosine pentose
Azacitidine amine Impurity 8 isomer
N-(formylamidino)-N'-Ribofuranosyl urea
Azacitidine impurity N
Azacitidine Related Compound-C(Isomer 3)
Azacitidine Related Compound-C Isomer-4
(2R,3R,4S,5R)-2-(acetoxymethyl)-5-(3-carbamoylguanidino)tetrahydrofuran-3,4-diyl diacetate
(2R,3R,4S,5R)-2-(acetoxymethyl)-5-(N-(hydroxymethyl)diazenecarboximidamido)tetrahydrofuran-3,4-diyl diacetate
(2R,3R,4S,5R)-2-(acetoxymethyl)-5-(3-(diaminomethylene)ureido)tetrahydrofuran-3,4-diyl diacetate
Azacitidine Impurity 4
(2R,3R,4S,5R)-2-(acetoxymethyl)-5-((Z)-3-(amino(formamido)methylene)ureido)tetrahydrofuran-3,4-diyl diacetate
Azacitidine Impurity 21
Azacitidine Impurity 33
N-ForMyl-D-ribofuranosyl-3-guanylurea(alpha/beta-Mixture)
(2R,3R,4S,5R)-2-(4-Amino-2-oxo-1,3,5-triazin-1(2H)-yl)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-3-yl acetate
Azacitidine Related Compound C Isomer-3 Acetate
beta-L-Ribofuranose
N-Formyl Guanylribosyl Urea
Guanylribosyl Urea
1,2,3,5-tetra-O-acetyl-D-xylofuranose
1,2,3,5-Tetra-O-acetyl-beta-L-xylofuranose
1,2,3,5-tetra-O-acetyl-D-lyxofuranose
Azacitidine Impurity 16
Azacitidine Impurity 2
Azacitidine Impurity 5 (Mixture of Diasteriomers)
Azacitidine Impurity 6
Azacitidine Amine impurity 3 isomer
Azacitidine Amine impurity 7 isomer
Azacitidine Amine impurity 9 isomer
Azacitidine Related compound C mixture of 4 isomer
Azacitidine Impurity 7
Azacitidine Impurity 8
Azacitidine Impurity 9
Azacitidine Impurity 10
Azacitidine Impurity 11
Azacitidine Impurity 1

Isotope Labelled Compounds

(13C5)-Azacitidine
Azacitidine-15N4
5-Azacytidine-15N4 5`-Monophosphate