Axitinib Related Compounds & Impurities

Axitinib is a selective VEGF receptor 1-3 inhibitor that suppresses tumour angiogenesis, used for advanced renal cell carcinoma.

Simson Pharma Limited along with its subsidiary offices Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) is a trusted manufacturer and supplier of high-quality pharmaceutical reference standards, offering a comprehensive portfolio of Axitinib reference standards, pharmacopeial and non-pharmacopeial Axitinib impurities, related compounds, related substances, metabolites, stable isotope-labelled compounds, deuterium labelled compounds and nitrosamine (N-NO) reference standards.

These materials support pharmaceutical research and development, product development, ANDA and DMF submissions, quality control (QC), analytical method development and validation, stability studies, impurity identification, and genotoxic impurity assessment.

Our Axitinib-related reference standards are thoroughly characterized using advanced analytical techniques and are supplied with comprehensive Certificates of Analysis (COA) and supporting analytical data from our USFDA certified, ISO 17025 and ISO 17034 accredited Lab, to meet global regulatory expectations. EP and USP traceable reference standards can also be provided upon request, subject to availability. Simson is also a provider of EP and USP traceable standards. To ensure consistent quality and reliability, our reference standards are periodically re-tested according to established quality management procedures.

Pharmaceutical Reference Standards / Impurity Standards

Axitinib
Axitinib
  • CAT. No.A740000
  • CAS. No.319460-85-0
  • Mol. F.C22H18N4OS
  • Mol. W.386.47 g/mol
  • Stock Status:Instock
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(Z)-Axitinib
(Z)-Axitinib
  • CAT. No.A740002
  • CAS. No.885126-40-9
  • Mol. F.C22H18N4OS
  • Mol. W.386.47 g/mol
  • Stock Status:Instock
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Axitinib impurity A
Axitinib impurity A
  • CAT. No.A740003
  • CAS. No.319472-78-1
  • Mol. F.C7H4I2N2
  • Mol. W.369.93 g/mol
  • Stock Status:Instock
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Axitinib EP Impurity B
Axitinib EP Impurity B
  • CAT. No.A740004
  • CAS. No.944835-85-2
  • Mol. F.C15H13N3OS
  • Mol. W.283.35 g/mol
  • Stock Status:Instock
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Axitinib EP Impurity C
Axitinib EP Impurity C
  • CAT. No.A740005
  • CAS. No.1959572-97-4
  • Mol. F.C15H13N302S
  • Mol. W.299.35 g/mol
  • Stock Status:Instock
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Axitinib EP Impurity D
Axitinib EP Impurity D
  • CAT. No.A740006
  • CAS. No.1959572-98-5
  • Mol. F.C17H15N3O3S
  • Mol. W.341.39 g/mol
  • Stock Status:Instock
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Axitinib Impurity F
Axitinib Impurity F
  • CAT. No.A740007
  • CAS. No.1443118-73-7
  • Mol. F.C22H20N4OS
  • Mol. W.388.49 g/mol
  • Stock Status:Instock
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Axitinib EP Impurity H
Axitinib EP Impurity H
  • CAT. No.A740008
  • CAS. No.NA
  • Mol. F.C24H20N4O2S
  • Mol. W.428.51 g/mol
  • Stock Status:Custom Synthesis
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Axitinib Impurity 31
Axitinib Impurity 31
  • CAT. No.A740009
  • CAS. No.NA
  • Mol. F.C22H18N4O2S
  • Mol. W.402.47 g/mol
  • Stock Status:Custom Synthesis
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Axitinib Impurity 4
Axitinib Impurity 4
  • CAT. No.A740010
  • CAS. No.1443118-73-7
  • Mol. F.C22H20N4OS
  • Mol. W.388.49 g/mol
  • Stock Status:Instock
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N-Methyl-2-((3-(2-(pyridin-2-yl)ethyl)-1H-indazol-6-yl)thio)benzamide
N-Methyl-2-((3-(2-(pyridin-2-yl)ethyl)-1H-indazol-6-yl)thio)benzamide
  • CAT. No.A740011
  • CAS. No.1443118-73-7
  • Mol. F.C22H20N4OS
  • Mol. W.388.49 g/mol
  • Stock Status:Custom Synthesis
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Axitinib Acid
Axitinib Acid
  • CAT. No.A740012
  • CAS. No.319462-34-5
  • Mol. F.C21H15N3O2S
  • Mol. W.373.43 g/mol
  • Stock Status:Instock
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Axitinib Dimer
Axitinib Dimer
  • CAT. No.A740013
  • CAS. No.1428728-84-0
  • Mol. F.C44H36N8O2S2
  • Mol. W.772.94 g/mol
  • Stock Status:Under Synthesis
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Axitinib Sulfoxide
Axitinib Sulfoxide
  • CAT. No.A740014
  • CAS. No.1347304-18-0
  • Mol. F.C22H18N4O2S
  • Mol. W.402.47 g/mol
  • Stock Status:Instock
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Axitinib Sulfone
Axitinib Sulfone
  • CAT. No.A740015
  • CAS. No.1348536-59-3
  • Mol. F.C22H18N4O3S
  • Mol. W.418.47 g/mol
  • Stock Status:Instock
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Axitinib Lactose Adduct
Axitinib Lactose Adduct
  • CAT. No.A740016
  • CAS. No.NA
  • Mol. F.C34H38N4O11S
  • Mol. W.710.75 g/mol
  • Stock Status:Custom Synthesis
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Axitinib Galactose Adduct
Axitinib Galactose Adduct
  • CAT. No.A740017
  • CAS. No.NA
  • Mol. F.C28H28N4O6S
  • Mol. W.548.61 g/mol
  • Stock Status:Custom Synthesis
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Axitinib N-Methyl Impurity
Axitinib N-Methyl Impurity
  • CAT. No.A740018
  • CAS. No.NA
  • Mol. F.C23H20N4OS
  • Mol. W.400.50 g/mol
  • Stock Status:Instock
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Axitinib Impurity 1
Axitinib Impurity 1
  • CAT. No.A740019
  • CAS. No.NA
  • Mol. F.C28H24N4O4S
  • Mol. W.512.58 g/mol
  • Stock Status:Custom Synthesis
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N-Methyl-2-[[3-[(1E)-2-(oxidopyridinyl) ethenyl]-1H-indazol-6-yl]-thiol]-benzamide
N-Methyl-2-[[3-[(1E)-2-(oxidopyridinyl) ethenyl]-1H-indazol-6-yl]-thiol]-benzamide
  • CAT. No.A740020
  • CAS. No.NA
  • Mol. F.C22H18N4O2S
  • Mol. W.402.47 g/mol
  • Stock Status:Custom Synthesis
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N-Methyl-2-[[3-[(1E)-2-(1-oxopyridinyl)ethenyl]-1-oxido-1H-indazol-6-y-sulfinyl]]benzamide
N-Methyl-2-[[3-[(1E)-2-(1-oxopyridinyl)ethenyl]-1-oxido-1H-indazol-6-y-sulfinyl]]benzamide
  • CAT. No.A740021
  • CAS. No.NA
  • Mol. F.C22H18N4O4S
  • Mol. W.434.47 g/mol
  • Stock Status:Custom Synthesis
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Axitinib Impurity 5
Axitinib Impurity 5
  • CAT. No.A740022
  • CAS. No.NA
  • Mol. F.C22H18N4O5S
  • Mol. W.450.47 g/mol
  • Stock Status:Custom Synthesis
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Axitinib Impurity 3
Axitinib Impurity 3
  • CAT. No.A740023
  • CAS. No.1348044-24-5
  • Mol. F.C22H18N4O3S
  • Mol. W.418.47 g/mol
  • Stock Status:Instock
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Axitinib-D3 Hydrate
Axitinib-D3 Hydrate
  • CAT. No.A740024
  • CAS. No.1126623-89-9(anhydrous);319460-85-0(unlabelled)
  • Mol. F.C22H15D3N4OS.H2O
  • Mol. W.423.50 g/mol
  • Stock Status:Custom Synthesis
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Axitinib Impurity 12
Axitinib Impurity 12
  • CAT. No.A740025
  • CAS. No.886230-77-9
  • Mol. F.C19H18IN3O
  • Mol. W.431.27 g/mol
  • Stock Status:Instock
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Axitinib Impurity 14
Axitinib Impurity 14
  • CAT. No.A740026
  • CAS. No.886230-76-8
  • Mol. F.C19H20N4O
  • Mol. W.320.39 g/mol
  • Stock Status:Custom Synthesis
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Axitinib Dimer Impurity 2
Axitinib Dimer Impurity 2
  • CAT. No.A740027
  • CAS. No.1428728-83-9
  • Mol. F.C44H36N8O2S2
  • Mol. W.772.94 g/mol
  • Stock Status:Under Synthesis
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Axitinib Thio Benzamide Impurity
Axitinib Thio Benzamide Impurity
  • CAT. No.A740028
  • CAS. No.885126-35-2
  • Mol. F.C27H26N4O2S
  • Mol. W.470.59 g/mol
  • Stock Status:Instock
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N-methyl-2-((6`-(2-(methylcarbamoyl)benzyl)-1H,1`H-[3,3`-biindazol]-6-yl)thio)benzamide
N-methyl-2-((6`-(2-(methylcarbamoyl)benzyl)-1H,1`H-[3,3`-biindazol]-6-yl)thio)benzamide
  • CAT. No.A740029
  • CAS. No.NA
  • Mol. F.C31H26N6O2S
  • Mol. W.546.64 g/mol
  • Stock Status:Custom Synthesis
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Axitinib N-Formyl Impurity
Axitinib N-Formyl Impurity
  • CAT. No.A740030
  • CAS. No.NA
  • Mol. F.C23H18N4O2S
  • Mol. W.414.48 g/mol
  • Stock Status:Custom Synthesis
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Axitinib N b glucuronide
Axitinib N b glucuronide
  • CAT. No.A740031
  • CAS. No.NA
  • Mol. F.C28H26N4O7S
  • Mol. W.562.59 g/mol
  • Stock Status:Custom Synthesis
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Axitinib Impurity 20
Axitinib Impurity 20
  • CAT. No.A740032
  • CAS. No.1443118-72-6
  • Mol. F.C29H25N5OS
  • Mol. W.491.61 g/mol
  • Stock Status:Custom Synthesis
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Axitinib N-Oxide
Axitinib N-Oxide
  • CAT. No.A740033
  • CAS. No.NA
  • Mol. F.C22H18N4O2S
  • Mol. W.402.47 g/mol
  • Stock Status:Custom Synthesis
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Axitinib N-Glucuronide (M7)
Axitinib N-Glucuronide (M7)
  • CAT. No.A740034
  • CAS. No.NA
  • Mol. F.C28H26N4O7S
  • Mol. W.562.59 g/mol
  • Stock Status:Custom Synthesis
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Axitinib Impurity 9
Axitinib Impurity 9
  • CAT. No.A740035
  • CAS. No.2527-58-4
  • Mol. F.C16H16N2O2S2
  • Mol. W.332.44 g/mol
  • Stock Status:Custom Synthesis
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Axitinib Form IV
Axitinib Form IV
  • CAT. No.A740036
  • CAS. No.NA
  • Mol. F.C22H18N4OS
  • Mol. W.386.47 g/mol
  • Stock Status:Custom Synthesis
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Axitinib Form SAB-1
Axitinib Form SAB-1
  • CAT. No.A740037
  • CAS. No.NA
  • Mol. F.C22H18N4OS
  • Mol. W.386.47 g/mol
  • Stock Status:Custom Synthesis
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Axitinib Impurity H
Axitinib Impurity H
  • CAT. No.A740038
  • CAS. No.1639137-80-6
  • Mol. F.C24H20N4O2S
  • Mol. W.428.51 g/mol
  • Stock Status:Instock
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Axitinib N-Oxide
Axitinib N-Oxide
  • CAT. No.A740039
  • CAS. No.NA
  • Mol. F.C22H18N4O2S
  • Mol. W.402.47 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Axitinib
N-Nitroso Axitinib
  • CAT. No.A740040
  • CAS. No.NA
  • Mol. F.C22H17N5O2S
  • Mol. W.415.47 g/mol
  • Stock Status:Custom Synthesis
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Axitinib Nitroso Impurity 2
Axitinib Nitroso Impurity 2
  • CAT. No.A740041
  • CAS. No.NA
  • Mol. F.C7H4IN3O
  • Mol. W.273.00 g/mol
  • Stock Status:Custom Synthesis
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Axitinib Nitroso Impurity 3
Axitinib Nitroso Impurity 3
  • CAT. No.A740042
  • CAS. No.NA
  • Mol. F.C15H12N4O2S
  • Mol. W.312.30 g/mol
  • Stock Status:Custom Synthesis
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Axitinib Nitroso Impurity 4
Axitinib Nitroso Impurity 4
  • CAT. No.A740043
  • CAS. No.NA
  • Mol. F.C15H11IN4O2S
  • Mol. W.438.20 g/mol
  • Stock Status:Custom Synthesis
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Axitinib Impurity 26
Axitinib Impurity 26
  • CAT. No.A740044
  • CAS. No.885126-34-1
  • Mol. F.C15H12IN3OS
  • Mol. W.409.20 g/mol
  • Stock Status:Custom Synthesis
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6-Iodo-1H-indazole
6-Iodo-1H-indazole
  • CAT. No.A740045
  • CAS. No.261953-36-0
  • Mol. F.C7H5IN2
  • Mol. W.244.03 g/mol
  • Stock Status:Under Synthesis
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Axitinib Impurity 7
Axitinib Impurity 7
  • CAT. No.A740046
  • CAS. No.NA
  • Mol. F.C22H16N6O3S
  • Mol. W.444.47 g/mol
  • Stock Status:Custom Synthesis
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Axitinib Impurity 6
Axitinib Impurity 6
  • CAT. No.A740047
  • CAS. No.NA
  • Mol. F.C22H18N4O4S
  • Mol. W.434.50 g/mol
  • Stock Status:Custom Synthesis
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Axitinib Impurity 10
Axitinib Impurity 10
  • CAT. No.A740048
  • CAS. No.2242852-05-5
  • Mol. F.C19H19N3O
  • Mol. W.305.37 g/mol
  • Stock Status:Custom Synthesis
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Axitinib Impurity 11
Axitinib Impurity 11
  • CAT. No.A740049
  • CAS. No.NA
  • Mol. F.C19H20IN3O
  • Mol. W.433.29 g/mol
  • Stock Status:Custom Synthesis
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Axitinib Impurity 13
Axitinib Impurity 13
  • CAT. No.A740050
  • CAS. No.1952288-48-0
  • Mol. F.C14H10IN3
  • Mol. W.347.15 g/mol
  • Stock Status:Custom Synthesis
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Isotope Labelled Compounds

Axitinib -13C-D3
Axitinib -13C-D3
  • CAT. No.A740001
  • CAS. No.NA
  • Mol. F.C2113CH15D3N4OS
  • Mol. W.390.49 g/mol
  • Stock Status:Instock
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