Alvimopan Related Compounds & Impurities

Alvimopan is a peripherally restricted mu-opioid receptor antagonist that accelerates GI recovery after bowel resection by blocking opioid-mediated motility suppression without CNS effects.

Simson Pharma Limited along with its subsidiary offices Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) is a trusted manufacturer and supplier of high-quality pharmaceutical reference standards, offering a comprehensive portfolio of Alvimopan reference standards, pharmacopeial and non-pharmacopeial Alvimopan impurities, related compounds, related substances, metabolites, stable isotope-labelled compounds, deuterium labelled compounds and nitrosamine (N-NO) reference standards.

These materials support pharmaceutical research and development, product development, ANDA and DMF submissions, quality control (QC), analytical method development and validation, stability studies, impurity identification, and genotoxic impurity assessment.

Our Alvimopan-related reference standards are thoroughly characterized using advanced analytical techniques and are supplied with comprehensive Certificates of Analysis (COA) and supporting analytical data from our USFDA certified, ISO 17025 and ISO 17034 accredited Lab, to meet global regulatory expectations. EP and USP traceable reference standards can also be provided upon request, subject to availability. Simson is also a provider of EP and USP traceable standards. To ensure consistent quality and reliability, our reference standards are periodically re-tested according to established quality management procedures.

Pharmaceutical Reference Standards / Impurity Standards

Alvimopan
Alvimopan
  • CAT. No.A1220000
  • CAS. No.156053-89-3
  • Mol. F.C25H32N2O4
  • Mol. W.424.53 g/mol
  • Stock Status:Custom Synthesis
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Alvimopan Dihydrate
Alvimopan Dihydrate
  • CAT. No.A1220000A
  • CAS. No.
  • Mol. F.C25H32N2O4.H2O
  • Mol. W.460.56 g/mol
  • Stock Status:Instock
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2-(2-benzylacryamido)aceticacid
2-(2-benzylacryamido)aceticacid
  • CAT. No.A1220004
  • CAS. No.NA
  • Mol. F.C12H13NO3
  • Mol. W.219.24 g/mol
  • Stock Status:Custom Synthesis
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Alvimopan Impurity 27
Alvimopan Impurity 27
  • CAT. No.A1220005
  • CAS. No.119193-19-0
  • Mol. F.C13H19NO
  • Mol. W.205.30 g/mol
  • Stock Status:Custom Synthesis
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2-((2R)-2-benzyl-3-((3R)-4-(3-hydroxyphenyl)-3-methylpiperidin-1-yl)propanamido)acetic acid
2-((2R)-2-benzyl-3-((3R)-4-(3-hydroxyphenyl)-3-methylpiperidin-1-yl)propanamido)acetic acid
  • CAT. No.A1220006
  • CAS. No.NA
  • Mol. F.C24H30N2O4
  • Mol. W.410.51 g/mol
  • Stock Status:Custom Synthesis
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(S)-2-benzyl-3-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-3,4-dimethylpiperidin-1-yl)propanamido)acetic acid
(S)-2-benzyl-3-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-3,4-dimethylpiperidin-1-yl)propanamido)acetic acid
  • CAT. No.A1220007
  • CAS. No.NA
  • Mol. F.C27H37N2O4
  • Mol. W.453.59 g/mol
  • Stock Status:Custom Synthesis
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Ethyl 2-((S)-2-benzyl-3-((3R,4R)-4-(-3-hydroxyphenyl)-3,4-dimethylpiperidin-1yl)propanamido)acetate hydrochloride
Ethyl 2-((S)-2-benzyl-3-((3R,4R)-4-(-3-hydroxyphenyl)-3,4-dimethylpiperidin-1yl)propanamido)acetate hydrochloride
  • CAT. No.A1220008
  • CAS. No.NA
  • Mol. F.C27H36N2O4
  • Mol. W.452.59 g/mol
  • Stock Status:Custom Synthesis
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Alvimopan Isomer(2R,3S,4S)
Alvimopan Isomer(2R,3S,4S)
  • CAT. No.A1220009
  • CAS. No.156130-44-8
  • Mol. F.C25H32N2O4
  • Mol. W.424.53 g/mol
  • Stock Status:Custom Synthesis
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2-((R)-2-benzyl-3-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperdin-1-yl)propanamido)acetic acid
2-((R)-2-benzyl-3-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperdin-1-yl)propanamido)acetic acid
  • CAT. No.A1220010
  • CAS. No.NA
  • Mol. F.C25H32N2O4
  • Mol. W.424.53 g/mol
  • Stock Status:Custom Synthesis
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(2S,3S,4S)-Alvimopan
(2S,3S,4S)-Alvimopan
  • CAT. No.A1220011
  • CAS. No.NA
  • Mol. F.C25H32N2O4
  • Mol. W.424.53 g/mol
  • Stock Status:Custom Synthesis
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Alvimopan Impurity 19
Alvimopan Impurity 19
  • CAT. No.A1220012
  • CAS. No.1314751-85-3
  • Mol. F.C15H21NO6S
  • Mol. W.343.39 g/mol
  • Stock Status:Custom Synthesis
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(3R,4R)-3,4-dimethyl piperidin-4-yl)phenol
(3R,4R)-3,4-dimethyl piperidin-4-yl)phenol
  • CAT. No.A1220013
  • CAS. No.119193-19-0
  • Mol. F.C13H19NO
  • Mol. W.205.30 g/mol
  • Stock Status:Custom Synthesis
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Alvimopan Impurity 18
Alvimopan Impurity 18
  • CAT. No.A1220017
  • CAS. No.145340-45-0
  • Mol. F.C17H25NO
  • Mol. W.259.39 g/mol
  • Stock Status:Custom Synthesis
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2-((R)-2-benzyl-3-((3S,4S)-4-(3-hydroxyphenyl)-3.4-dimethylpiperidin-1 yl)propanamido)acetic acid hydrate
2-((R)-2-benzyl-3-((3S,4S)-4-(3-hydroxyphenyl)-3.4-dimethylpiperidin-1 yl)propanamido)acetic acid hydrate
  • CAT. No.A1220018
  • CAS. No.156130-44-8
  • Mol. F.C25H34N2O5
  • Mol. W.442.55 g/mol
  • Stock Status:Custom Synthesis
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Alvimopan Impurity 20
Alvimopan Impurity 20
  • CAT. No.A1220019
  • CAS. No.1314751-83-1
  • Mol. F.C14H19NO4
  • Mol. W.265.30 g/mol
  • Stock Status:Custom Synthesis
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Alvimopan Impurity 21
Alvimopan Impurity 21
  • CAT. No.A1220020
  • CAS. No.660848-81-7
  • Mol. F.C14H17NO3
  • Mol. W.247.29 g/mol
  • Stock Status:Custom Synthesis
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Alvimopan Impurity 22
Alvimopan Impurity 22
  • CAT. No.A1220021
  • CAS. No.1852472-89-9
  • Mol. F.C13H17NO6S
  • Mol. W.315.34 g/mol
  • Stock Status:Custom Synthesis
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Alvimopan Impurity 23
Alvimopan Impurity 23
  • CAT. No.A1220022
  • CAS. No.1314751-81-9
  • Mol. F.C21H25NO4
  • Mol. W.355.43 g/mol
  • Stock Status:Custom Synthesis
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Alvimopan Impurity 24
Alvimopan Impurity 24
  • CAT. No.A1220023
  • CAS. No.1237735-54-4
  • Mol. F.C17H18O3
  • Mol. W.270.32 g/mol
  • Stock Status:Custom Synthesis
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Alvimopan Impurity 25
Alvimopan Impurity 25
  • CAT. No.A1220024
  • CAS. No.2184736-45-4
  • Mol. F.C15H21NO6S
  • Mol. W.343.40 g/mol
  • Stock Status:Custom Synthesis
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Alvimopan Impurity 28
Alvimopan Impurity 28
  • CAT. No.A1220025
  • CAS. No.145678-87-1
  • Mol. F.C13H19NO
  • Mol. W.205.30 g/mol
  • Stock Status:Custom Synthesis
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Alvimopan Impurity 14
Alvimopan Impurity 14
  • CAT. No.A1220027
  • CAS. No.76932-18-8
  • Mol. F.C12H13NO3
  • Mol. W.219.24 g/mol
  • Stock Status:Custom Synthesis
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Alvimopan DMP Ester Impurity
Alvimopan DMP Ester Impurity
  • CAT. No.A1220028
  • CAS. No.1314751-88-6
  • Mol. F.C27H36N2O4.HCl
  • Mol. W.489.05 g/mol
  • Stock Status:Custom Synthesis
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Alvimopan Desmethyl Impurity
Alvimopan Desmethyl Impurity
  • CAT. No.A1220029
  • CAS. No.NA
  • Mol. F.C24H30N2O4
  • Mol. W.410.51 g/mol
  • Stock Status:Custom Synthesis
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Alvimopan Impurity 1
Alvimopan Impurity 1
  • CAT. No.A1220030
  • CAS. No.NA
  • Mol. F.C24H30N2O4
  • Mol. W.410.51 g/mol
  • Stock Status:Custom Synthesis
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Alvimopan N-Nitroso impurity 1
Alvimopan N-Nitroso impurity 1
  • CAT. No.A1220032
  • CAS. No.NA
  • Mol. F.C13H18N2O2
  • Mol. W.234.29 g/mol
  • Stock Status:Custom Synthesis
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Metabolites

Alvimopan Metabolite
Alvimopan Metabolite
  • CAT. No.A1220014
  • CAS. No.NA
  • Mol. F.C23H29NO3
  • Mol. W.367.49g/mol
  • Stock Status:Custom Synthesis
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Alvimopan Acyl Glucuronide
Alvimopan Acyl Glucuronide
  • CAT. No.A1220015
  • CAS. No.1260616-95-2
  • Mol. F.C31H40N2O10
  • Mol. W.600.67g/mol
  • Stock Status:Please Enquire
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Alvimophan metabolite (ADL08-0011)
Alvimophan metabolite (ADL08-0011)
  • CAT. No.A1220016
  • CAS. No.156130-41-5
  • Mol. F.C23H29NO3
  • Mol. W.367.48 g/mol
  • Stock Status:Custom Synthesis
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Isotope Labelled Compounds

Alvimopan-D5
Alvimopan-D5
  • CAT. No.A1220001
  • CAS. No.1217616-62-0
  • Mol. F.C25H27D5N2O4
  • Mol. W.429.56 g/mol
  • Stock Status:Custom Synthesis
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Alvimopan-D5 desglycine Metabolite
Alvimopan-D5 desglycine Metabolite
  • CAT. No.A1220002
  • CAS. No.NA
  • Mol. F.C23H24NO3D5
  • Mol. W.372.52 g/mol
  • Stock Status:Custom Synthesis
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Alvimopan-d7
Alvimopan-d7
  • CAT. No.A1220003
  • CAS. No.1261396-48-8
  • Mol. F.C25H25D7N2O4
  • Mol. W.431.58 g/mol
  • Stock Status:Limited Stock
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Alvimopan metabolite D7 (ADL08-0011), hydrochloride
Alvimopan metabolite D7 (ADL08-0011), hydrochloride
  • CAT. No.A1220026
  • CAS. No.1261396-48-8(unlabeled)
  • Mol. F.C25H26D7ClN2O4
  • Mol. W.468.04 g/mol
  • Stock Status:Custom Synthesis
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