Carbamazepine Related Compounds & Impurities

Carbamazepine is a voltage-gated sodium-channel blocker used as first-line antiepileptic for focal seizures and trigeminal neuralgia.

Simson Pharma Limited along with its subsidiary offices Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) is a trusted manufacturer and supplier of high-quality pharmaceutical reference standards, offering a comprehensive portfolio of Carbamazepine reference standards, pharmacopeial and non-pharmacopeial Carbamazepine impurities, related compounds, related substances, metabolites, stable isotope-labelled compounds, deuterium labelled compounds and nitrosamine (N-NO) reference standards.

These materials support pharmaceutical research and development, product development, ANDA and DMF submissions, quality control (QC), analytical method development and validation, stability studies, impurity identification, and genotoxic impurity assessment.

Our Carbamazepine-related reference standards are thoroughly characterized using advanced analytical techniques and are supplied with comprehensive Certificates of Analysis (COA) and supporting analytical data from our USFDA certified, ISO 17025 and ISO 17034 accredited Lab, to meet global regulatory expectations. EP and USP traceable reference standards can also be provided upon request, subject to availability. Simson is also a provider of EP and USP traceable standards. To ensure consistent quality and reliability, our reference standards are periodically re-tested according to established quality management procedures.

Pharmaceutical Reference Standards / Impurity Standards

Carbamazepine
Carbamazepine EP Impurity A
Carbamazepine EP Impurity B
Carbamazepine EP Impurity C
Carbamazepine EP Impurity D
Carbamazepine EP Impurity E
Carbamazepine EP Impurity F
Acridine
Carbamazepine EP Impurity G
3-Hydroxy Carbamazepine
2-Hydroxy Carbamazepine
2,2`-Ethylenedianiline
Carbamazepine Dinitro Impurity
(6,11-Dihydro-5H-dibenzo[b,e]azepin-6-yl)methanamine
10,11-Dihydro-10-Hydroxy Carbamazepine
Carbamazepine Impurity 11
Carbamazepine Dihydrate
10,11-Dihydroxycarbamazepine
10-Methylacridan
(6,11-dihydro-5H-dibenzo[b,e]azepin-6-yl)methanamine succinate
Carbamazepine Impurity 2
Carbamazepine impurity 3
Carbamazepine Impurity 4
N-Nitroso Carbamazepine EP Impurity E
N-Nitroso Carbamazepine EP Impurity D
10-Acetoxycarbamazepine

Metabolites

10-hydroxy carbamazepine glucuronide sodium

Isotope Labelled Compounds

Carbamazepine D10
Carbamazepine 10,11-Epoxide-D2
Carbamazepine 10,11-Epoxide-D8
Carbamazepine-10,11-epoxide D10
Carbamazepine-D2
Carbamazepine-D8