Carvedilol Related Compounds & Impurities

Carvedilol is a non-selective beta-adrenergic and alpha-1 receptor blocker used for hypertension, stable angina and heart failure with reduced ejection fraction.

Simson Pharma Limited along with its subsidiary offices Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) is a trusted manufacturer and supplier of high-quality pharmaceutical reference standards, offering a comprehensive portfolio of Carvedilol reference standards, pharmacopeial and non-pharmacopeial Carvedilol impurities, related compounds, related substances, metabolites, stable isotope-labelled compounds, deuterium labelled compounds and nitrosamine (N-NO) reference standards.

These materials support pharmaceutical research and development, product development, ANDA and DMF submissions, quality control (QC), analytical method development and validation, stability studies, impurity identification, and genotoxic impurity assessment.

Our Carvedilol-related reference standards are thoroughly characterized using advanced analytical techniques and are supplied with comprehensive Certificates of Analysis (COA) and supporting analytical data from our USFDA certified, ISO 17025 and ISO 17034 accredited Lab, to meet global regulatory expectations. EP and USP traceable reference standards can also be provided upon request, subject to availability. Simson is also a provider of EP and USP traceable standards. To ensure consistent quality and reliability, our reference standards are periodically re-tested according to established quality management procedures.

Pharmaceutical Reference Standards / Impurity Standards

Carvedilol
Carvedilol
  • CAT. No.C020000
  • CAS. No.72956-09-3
  • Mol. F.C24H26N2O4
  • Mol. W.406.48 g/mol
  • Stock Status:Instock
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Carvedilol Phosphate Hemihydrate
Carvedilol Phosphate Hemihydrate
  • CAT. No.C020000A
  • CAS. No.610309-89-2
  • Mol. F.C48H52N4O8.H2O.H6O8P2
  • Mol. W.1026.95 g/mol
  • Stock Status:Custom Synthesis
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Carvedilol EP Impurity A
Carvedilol EP Impurity A
  • CAT. No.C020001
  • CAS. No.1198090-73-1
  • Mol. F.C36H43N3O7
  • Mol. W.629.74 g/mol
  • Stock Status:Instock
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Carvedilol EP Impurity B
Carvedilol EP Impurity B
  • CAT. No.C020002
  • CAS. No.918903-20-5
  • Mol. F.C39H39N3O6
  • Mol. W.645.74 g/mol
  • Stock Status:Instock
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Carvedilol EP Impurity C
Carvedilol EP Impurity C
  • CAT. No.C020003
  • CAS. No.72955-94-3
  • Mol. F.C31H32N2O4
  • Mol. W.496.60 g/mol
  • Stock Status:Instock
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4-(2,3-Epoxypropoxy)carbazole
4-(2,3-Epoxypropoxy)carbazole
  • CAT. No.C020004
  • CAS. No.51997-51-4
  • Mol. F.C15H13NO2
  • Mol. W.239.27 g/mol
  • Stock Status:Instock
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Carvedilol EP Impurity D Hydrochloride
Carvedilol EP Impurity D Hydrochloride
  • CAT. No.C020004A
  • CAS. No.51997-51-4(base)
  • Mol. F.C15H13NO2.HCl
  • Mol. W.275.73 g/mol
  • Stock Status:Instock
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2-(2-Methoxyphenoxy)ethan-1-amine hydrochloride Hydrate
2-(2-Methoxyphenoxy)ethan-1-amine hydrochloride Hydrate
  • CAT. No.C020005
  • CAS. No.2057412-43-6
  • Mol. F.C9H16ClNO3
  • Mol. W.221.68 g/mol
  • Stock Status:Instock
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Carvedilol EP Impuity E
Carvedilol EP Impuity E
  • CAT. No.C020005A
  • CAS. No.1836-62-0
  • Mol. F.C9H13NO2
  • Mol. W.167.21 g/mol
  • Stock Status:Instock
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Carvedilol R Isomer
Carvedilol R Isomer
  • CAT. No.C020006
  • CAS. No.95093-99-5
  • Mol. F.C24H26N2O4
  • Mol. W.406.47 g/mol
  • Stock Status:Custom Synthesis
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Carvedilol S Isomer
Carvedilol S Isomer
  • CAT. No.C020007
  • CAS. No.95094-00-1
  • Mol. F.C24H26N2O4
  • Mol. W.406.47 g/mol
  • Stock Status:Custom Synthesis
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N-(2-(2-Methoxyphenoxy)ethyl)benzylamine hydrochloride
N-(2-(2-Methoxyphenoxy)ethyl)benzylamine hydrochloride
  • CAT. No.C020008
  • CAS. No.3246-03-5
  • Mol. F.C16H19NO2.HCl
  • Mol. W.293.78 g/mol
  • Stock Status:Limited Stock
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Carvedilol Impurity 11
Carvedilol Impurity 11
  • CAT. No.C020009
  • CAS. No.NA
  • Mol. F.C26H28N2O5
  • Mol. W.448.51 g/mol
  • Stock Status:Instock
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Carvedilol Impurity H
Carvedilol Impurity H
  • CAT. No.C020010
  • CAS. No.NA
  • Mol. F.C25H26N2O5
  • Mol. W.434.48 g/mol
  • Stock Status:Instock
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Carvedilol Bis alkylpyrocatechol Derivative
Carvedilol Bis alkylpyrocatechol Derivative
  • CAT. No.C020011
  • CAS. No.1346602-98-9
  • Mol. F.C40H42N4O6
  • Mol. W.674.78 g/mol
  • Stock Status:Instock
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4`-Hydroxyphenyl Carvedilol
4`-Hydroxyphenyl Carvedilol
  • CAT. No.C020012
  • CAS. No.142227-49-4
  • Mol. F.C24H26N2O5
  • Mol. W.422.47 g/mol
  • Stock Status:Instock
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4-Hydroxy carbazole
4-Hydroxy carbazole
  • CAT. No.C020014
  • CAS. No.52602-39-8
  • Mol. F.C12H9NO
  • Mol. W.183.2 g/mol
  • Stock Status:Instock
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Carvedilol 4-Hydroxycarbazole Impurity
Carvedilol 4-Hydroxycarbazole Impurity
  • CAT. No.C020015
  • CAS. No.52602-39-8
  • Mol. F.C12H9NO
  • Mol. W.183.21 g/mol
  • Stock Status:Instock
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Carvedilol Impurity 1
Carvedilol Impurity 1
  • CAT. No.C020016
  • CAS. No.51997-51-4
  • Mol. F.C15H13NO2
  • Mol. W.239.27 g/mol
  • Stock Status:Instock
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2-(2-Methoxyphenoxy)ethylamine Hydrochloride
2-(2-Methoxyphenoxy)ethylamine Hydrochloride
  • CAT. No.C020017
  • CAS. No.64464-07-9
  • Mol. F.C9H13NO2.HCl
  • Mol. W.203.67 g/mol
  • Stock Status:Instock
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2-(2-Aminoethoxy)anisole
2-(2-Aminoethoxy)anisole
  • CAT. No.C020018
  • CAS. No.1836-62-0
  • Mol. F.C9H13NO2
  • Mol. W.167.21 g/mol
  • Stock Status:Custom Synthesis
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Carvedilol Propanediol Impurity
Carvedilol Propanediol Impurity
  • CAT. No.C020020
  • CAS. No.123119-89-1
  • Mol. F.C15H15NO3
  • Mol. W.257.28 g/mol
  • Stock Status:Instock
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N-Isopropyl Carvedilol
N-Isopropyl Carvedilol
  • CAT. No.C020021
  • CAS. No.1246819-01-1
  • Mol. F.C27H32N2O4
  • Mol. W.448.55 g/mol
  • Stock Status:Instock
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4-(oxiran-2-ylmethoxy)-9-(oxiran-2-ylmethyl)-9H-carbazole  
4-(oxiran-2-ylmethoxy)-9-(oxiran-2-ylmethyl)-9H-carbazole  
  • CAT. No.C020022
  • CAS. No.1198090-71-9
  • Mol. F.C18H17NO3
  • Mol. W.295.33 g/mol
  • Stock Status:Custom Synthesis
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1-(9H-carbazol-4-yloxy)-3-chloropropan-2-ol
1-(9H-carbazol-4-yloxy)-3-chloropropan-2-ol
  • CAT. No.C020023
  • CAS. No.1187921-93-2
  • Mol. F.C15H14ClNO2
  • Mol. W.275.73 g/mol
  • Stock Status:Custom Synthesis
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Carvedilol Impurity 4
Carvedilol Impurity 4
  • CAT. No.C020024
  • CAS. No.72955-96-5
  • Mol. F.C15H16N2O2
  • Mol. W.256.30 g/mol
  • Stock Status:Custom Synthesis
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N-[2-(2-methoxyphenoxy)ethyl]acetamide
N-[2-(2-methoxyphenoxy)ethyl]acetamide
  • CAT. No.C020025
  • CAS. No.293738-17-7
  • Mol. F.C11H15NO3
  • Mol. W.209.24 g/mol
  • Stock Status:Custom Synthesis
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N-(2-(2-Methoxyphenoxy)ethyl)-N-(3-(9H-carbazol-4-yloxy)-2-hydroxypropyl)acetamide
N-(2-(2-Methoxyphenoxy)ethyl)-N-(3-(9H-carbazol-4-yloxy)-2-hydroxypropyl)acetamide
  • CAT. No.C020026
  • CAS. No.141353-76-6
  • Mol. F.C26H28N2O5
  • Mol. W.448.51 g/mol
  • Stock Status:Custom Synthesis
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Carvedilol Ketone Impurity
Carvedilol Ketone Impurity
  • CAT. No.C020027
  • CAS. No.933442-50-3
  • Mol. F.C24H24N2O4
  • Mol. W.404.46 g/mol
  • Stock Status:Custom Synthesis
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N-Methyl Carvedilol
N-Methyl Carvedilol
  • CAT. No.C020028
  • CAS. No.72956-35-5
  • Mol. F.C25H28N2O4
  • Mol. W.420.10 g/mol
  • Stock Status:Instock
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N-Methyl Carvedilol Hydrochloride
N-Methyl Carvedilol Hydrochloride
  • CAT. No.C020029
  • CAS. No.1346599-33-4
  • Mol. F.C25H29ClN2O4
  • Mol. W.456.96 g/mol
  • Stock Status:Custom Synthesis
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5`-Hydroxyphenyl Carvedilol
5`-Hydroxyphenyl Carvedilol
  • CAT. No.C020030
  • CAS. No.142227-51-8
  • Mol. F.C24H26N2O5
  • Mol. W.422.47 g/mol
  • Stock Status:Instock
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Carvedilol Biscarbazole Impurity
Carvedilol Biscarbazole Impurity
  • CAT. No.C020031
  • CAS. No.1276477-91-8
  • Mol. F.C27H22N2O3
  • Mol. W.422.48 g/mol
  • Stock Status:Instock
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6,7,8,9-Tetrahydro Carvedilol
6,7,8,9-Tetrahydro Carvedilol
  • CAT. No.C020032
  • CAS. No.1246820-73-4
  • Mol. F.C24H30N2O4
  • Mol. W.410.51 g/mol
  • Stock Status:Under Synthesis
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Carvedilol Propanediol Impurity
Carvedilol Propanediol Impurity
  • CAT. No.C020035
  • CAS. No.123119-89-1
  • Mol. F.C15H15NO3
  • Mol. W.257.28 g/mol
  • Stock Status:Custom Synthesis
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Carvedilol EP Impurity D
Carvedilol EP Impurity D
  • CAT. No.C020036
  • CAS. No.1391052-16-6
  • Mol. F.C39H39N3O6
  • Mol. W.645.74 g/mol
  • Stock Status:Under Synthesis
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Carvedilol Impurity 6
Carvedilol Impurity 6
  • CAT. No.C020037
  • CAS. No.1059573-45-3
  • Mol. F.C33H36N2O6
  • Mol. W.556.65 g/mol
  • Stock Status:Instock
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N-formyl Carvedilol
N-formyl Carvedilol
  • CAT. No.C020038
  • CAS. No.NA
  • Mol. F.C25H26N2O5
  • Mol. W.434.48 g/mol
  • Stock Status:Instock
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Carvedilol Phosphate Hydrate
Carvedilol Phosphate Hydrate
  • CAT. No.C020042
  • CAS. No.NA
  • Mol. F.C24H26N2O4.H2O.H3O4P
  • Mol. W.522.49 g/mol
  • Stock Status:Custom Synthesis
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Carvedilol USP Related Compound E (Hydrochloride Hydrate)
Carvedilol USP Related Compound E (Hydrochloride Hydrate)
  • CAT. No.C020043
  • CAS. No.2057412-43-6
  • Mol. F.C9H16ClNO3
  • Mol. W.211.68 g/mol
  • Stock Status:Custom Synthesis
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2-(2-Methoxyphenoxy)ethan-1-amine hydrochloride Hydrate
2-(2-Methoxyphenoxy)ethan-1-amine hydrochloride Hydrate
  • CAT. No.C020043A
  • CAS. No.2057412-43-6
  • Mol. F.C9H16ClNO3
  • Mol. W.221.68 g/mol
  • Stock Status:Custom Synthesis
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Carvedilol Impurity 5
Carvedilol Impurity 5
  • CAT. No.C020044
  • CAS. No.NA
  • Mol. F.C15H15NO2
  • Mol. W.241.29 g/mol
  • Stock Status:Instock
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1-(2-chloroethoxy)-2-methoxybenzene
1-(2-chloroethoxy)-2-methoxybenzene
  • CAT. No.C020046
  • CAS. No.53815-60-4
  • Mol. F.C9H11ClO2
  • Mol. W.186.64 g/mol
  • Stock Status:Custom Synthesis
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Carvedilol O-Desmethyl Impurity
Carvedilol O-Desmethyl Impurity
  • CAT. No.C020047
  • CAS. No.72956-44-6
  • Mol. F.C23H24N2O4
  • Mol. W.392.45 g/mol
  • Stock Status:Custom Synthesis
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Nitroso-4-Hydroxy Carbazole Carvedilol
Nitroso-4-Hydroxy Carbazole Carvedilol
  • CAT. No.C020048
  • CAS. No.NA
  • Mol. F.C12H8N2O2
  • Mol. W.212.20 g/mol
  • Stock Status:Custom Synthesis
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Nitroso-Epoxy propoxy Carbazole
Nitroso-Epoxy propoxy Carbazole
  • CAT. No.C020049
  • CAS. No.NA
  • Mol. F.C15H12N2O3
  • Mol. W.268.27 g/mol
  • Stock Status:Instock
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Nitroso Carvedilol
Nitroso Carvedilol
  • CAT. No.C020050
  • CAS. No.NA
  • Mol. F.C24H25N3O5
  • Mol. W.435.47 g/mol
  • Stock Status:Instock
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1-Hydroxy Carvedilol
1-Hydroxy Carvedilol
  • CAT. No.C020051
  • CAS. No.146574-41-6
  • Mol. F.C24H26N2O5
  • Mol. W.422.48 g/mol
  • Stock Status:Custom Synthesis
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8-Hydroxy Carvedilol
8-Hydroxy Carvedilol
  • CAT. No.C020052
  • CAS. No.NA
  • Mol. F.C24H26N2O5
  • Mol. W.422.47 g/mol
  • Stock Status:Custom Synthesis
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Carvedilol Nitroso Impurity 2
Carvedilol Nitroso Impurity 2
  • CAT. No.C020055
  • CAS. No.NA
  • Mol. F.C24H25N3O5
  • Mol. W.435.50 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Carvedilol
N-Nitroso Carvedilol
  • CAT. No.C020056
  • CAS. No.2248746-67-8
  • Mol. F.C24H25N3O5
  • Mol. W.435.47 g/mol
  • Stock Status:Instock
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DiNitroso-Carvedilol
DiNitroso-Carvedilol
  • CAT. No.C020059
  • CAS. No.NA
  • Mol. F.C24H24N4O6
  • Mol. W.464.47 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Carvedilol Carbazole Impurity
N-Nitroso Carvedilol Carbazole Impurity
  • CAT. No.C020060
  • CAS. No.2788-23-0
  • Mol. F.C12H8N2O
  • Mol. W.196.20 g/mol
  • Stock Status:Custom Synthesis
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(R)-(+)-4`-Hydroxyphenyl Carvedilol
(R)-(+)-4`-Hydroxyphenyl Carvedilol
  • CAT. No.C020061
  • CAS. No.1217770-29-0
  • Mol. F.C24H26N2O5
  • Mol. W.422.47 g/mol
  • Stock Status:Custom Synthesis
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1-((2-(2-methoxyphenoxy)ethyl)amino)-3-((9-nitroso-9H-carbazol-4- yl)oxy)propan-2-yl dihydrogen phosphate
1-((2-(2-methoxyphenoxy)ethyl)amino)-3-((9-nitroso-9H-carbazol-4- yl)oxy)propan-2-yl dihydrogen phosphate
  • CAT. No.C020062
  • CAS. No.NA
  • Mol. F.C24H26N3O8P
  • Mol. W.515.45 g/mol
  • Stock Status:Custom Synthesis
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1-((9H-carbazol-4-yl)oxy)-3-((2-(2- methoxyphenoxy)ethyl)(nitroso)amino)propan-2-yl dihydrogen phosphate
1-((9H-carbazol-4-yl)oxy)-3-((2-(2- methoxyphenoxy)ethyl)(nitroso)amino)propan-2-yl dihydrogen phosphate
  • CAT. No.C020063
  • CAS. No.NA
  • Mol. F.C24H26N3O8P
  • Mol. W.515.45 g/mol
  • Stock Status:Custom Synthesis
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1-((9H-carbazol-4-yl)oxy)-3-(nitrosoamino)propan-2-yl dihydrogen phosphate
1-((9H-carbazol-4-yl)oxy)-3-(nitrosoamino)propan-2-yl dihydrogen phosphate
  • CAT. No.C020064
  • CAS. No.NA
  • Mol. F.C15H16N3O6P
  • Mol. W.365.28 g/mol
  • Stock Status:Custom Synthesis
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1-((9-nitroso-9H-carbazol-4-yl)oxy)-3-(nitrosoamino)propan-2-yl dihydrogen
1-((9-nitroso-9H-carbazol-4-yl)oxy)-3-(nitrosoamino)propan-2-yl dihydrogen
  • CAT. No.C020066
  • CAS. No.NA
  • Mol. F.C15H15N4O7P
  • Mol. W.394.28 g/mol
  • Stock Status:Custom Synthesis
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Carvedilol Form-II
Carvedilol Form-II
  • CAT. No.C020067
  • CAS. No.72956-09-3
  • Mol. F.C24H26N2O4
  • Mol. W.406.48 g/mol
  • Stock Status:Custom Synthesis
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Carvedilol Phosphate
Carvedilol Phosphate
  • CAT. No.C020068
  • CAS. No.374779-45-0
  • Mol. F.C24H29N2O8P
  • Mol. W.504.47 g/mol
  • Stock Status:Custom Synthesis
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Carvedilol Impurity 18
Carvedilol Impurity 18
  • CAT. No.C020069
  • CAS. No.1059573-38-4
  • Mol. F.C24H26N2O5
  • Mol. W.422.47 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Carvedilol EP Impurity A
N-Nitroso Carvedilol EP Impurity A
  • CAT. No.C020071
  • CAS. No.NA
  • Mol. F.C36H42N4O8
  • Mol. W.658.74 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Carvedilol EP Impurity D
N-Nitroso Carvedilol EP Impurity D
  • CAT. No.C020072
  • CAS. No.NA
  • Mol. F.C39H38N4O7
  • Mol. W.674.74 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Carvedilol USP Related Compound F
N-Nitroso Carvedilol USP Related Compound F
  • CAT. No.C020073
  • CAS. No.NA
  • Mol. F.C24H29N3O5.C2H4O2
  • Mol. W.499.56 g/mol
  • Stock Status:Custom Synthesis
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Metabolites

Carvedilol beta-D-Glucuronide
Carvedilol beta-D-Glucuronide
  • CAT. No.C020053
  • CAS. No.114869-83-9
  • Mol. F.C30H34N2O10
  • Mol. W.582.60 g/mol
  • Stock Status:Custom Synthesis
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Isotope Labelled Compounds

Carvedilol-D4
Carvedilol-D4
  • CAT. No.C020013
  • CAS. No.1133705-56-2
  • Mol. F.C24H22D4N2O4
  • Mol. W.410.50 g/mol
  • Stock Status:Under Synthesis
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4`-Hydroxyphenyl Carvedilol-D5
4`-Hydroxyphenyl Carvedilol-D5
  • CAT. No.C020019
  • CAS. No.1261395-96-3
  • Mol. F.C24H21D5N2O5
  • Mol. W.427.50 g/mol
  • Stock Status:Under Synthesis
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Carvedilol-D5
Carvedilol-D5
  • CAT. No.C020033
  • CAS. No.929106-58-1
  • Mol. F.C24H21D5N2O4
  • Mol. W.411.51 g/mol
  • Stock Status:Limited Stock
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Carvedilol-d3
Carvedilol-d3
  • CAT. No.C020054
  • CAS. No.1020719-25-8
  • Mol. F.C24H23D3N2O4
  • Mol. W.409.49 g/mol
  • Stock Status:Instock
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(S)-(-)-Carvedilol-D4
(S)-(-)-Carvedilol-D4
  • CAT. No.C020057
  • CAS. No.NA
  • Mol. F.C24H22D4N2O4
  • Mol. W.410.50 g/mol
  • Stock Status:Custom Synthesis
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R-(+)-Carvedilol-D4
R-(+)-Carvedilol-D4
  • CAT. No.C020058
  • CAS. No.NA
  • Mol. F.C24H22D4N2O4
  • Mol. W.410.50 g/mol
  • Stock Status:Custom Synthesis
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5`-Hydroxyphenyl Carvedilol D5
5`-Hydroxyphenyl Carvedilol D5
  • CAT. No.C020070
  • CAS. No.1189704-21-9
  • Mol. F.C24H21D5N2O5
  • Mol. W.427.51 g/mol
  • Stock Status:Custom Synthesis
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