Cetirizine Hydrochloride Related Compounds & Impurities

Cetirizine Hydrochloride is a second-generation non-sedating H1-receptor antihistamine widely used for allergic rhinitis, urticaria and hay fever.

Simson Pharma Limited along with its subsidiary offices Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) is a trusted manufacturer and supplier of high-quality pharmaceutical reference standards, offering a comprehensive portfolio of Cetirizine Hydrochloride reference standards, pharmacopeial and non-pharmacopeial Cetirizine Hydrochloride impurities, related compounds, related substances, metabolites, stable isotope-labelled compounds, deuterium labelled compounds and nitrosamine (N-NO) reference standards.

These materials support pharmaceutical research and development, product development, ANDA and DMF submissions, quality control (QC), analytical method development and validation, stability studies, impurity identification, and genotoxic impurity assessment.

Our Cetirizine Hydrochloride-related reference standards are thoroughly characterized using advanced analytical techniques and are supplied with comprehensive Certificates of Analysis (COA) and supporting analytical data from our USFDA certified, ISO 17025 and ISO 17034 accredited Lab, to meet global regulatory expectations. EP and USP traceable reference standards can also be provided upon request, subject to availability. Simson is also a provider of EP and USP traceable standards. To ensure consistent quality and reliability, our reference standards are periodically re-tested according to established quality management procedures.

Pharmaceutical Reference Standards / Impurity Standards

Cetrizine
Cetrizine
  • CAT. No.C100000
  • CAS. No.83881-51-0
  • Mol. F.C21H25ClN2O3
  • Mol. W.388.89 g/mol
  • Stock Status:Custom Synthesis
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Cetrizine Dihydrochloride
Cetrizine Dihydrochloride
  • CAT. No.C100000A
  • CAS. No.83881-52-1
  • Mol. F.C21H25ClN2O3.2HCl
  • Mol. W.461.81 g/mol
  • Stock Status:Instock
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Cetirizine EP Impurity B
Cetirizine EP Impurity B
  • CAT. No.C100002
  • CAS. No.113740-61-7
  • Mol. F.C19H21ClN2O2
  • Mol. W.344.84 g/mol
  • Stock Status:Instock
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Cetirizine EP Impurity B Hydrochloride
Cetirizine EP Impurity B Hydrochloride
  • CAT. No.C100002A
  • CAS. No.113740-61-7(free base)
  • Mol. F.C19H21ClN2O2.HCl
  • Mol. W.381.30 g/mol
  • Stock Status:Instock
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Cetirizine EP Impurity B Dihydrochloride
Cetirizine EP Impurity B Dihydrochloride
  • CAT. No.C100002B
  • CAS. No.1000690-91-4;113740-61-7(FreeAcid)
  • Mol. F.C19H21ClN2O2.2HCl
  • Mol. W.417.76 g/mol
  • Stock Status:Instock
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Levocetirizine EP Impurity C Dihydrochloride
Levocetirizine EP Impurity C Dihydrochloride
  • CAT. No.C100003
  • CAS. No.2702511-37-1
  • Mol. F.C21H27Cl3N2O3
  • Mol. W.461.81 g/mol
  • Stock Status:Limited Stock
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Levocetirizine EP Impurity F
Levocetirizine EP Impurity F
  • CAT. No.C100003A
  • CAS. No.83881-59-8
  • Mol. F.C21H25ClN2O3
  • Mol. W.388.89 g/mol
  • Stock Status:Instock
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Cetirizine EP Impurity D Dihydrochloride
Cetirizine EP Impurity D Dihydrochloride
  • CAT. No.C100004A
  • CAS. No.856841-95-7
  • Mol. F.C30H30Cl4N2
  • Mol. W.560.40 g/mol
  • Stock Status:Instock
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Hydroxyzine Acetic Acid Dihydrochloride
Hydroxyzine Acetic Acid Dihydrochloride
  • CAT. No.C100005
  • CAS. No.83881-56-5
  • Mol. F.C23H31N2O4Cl3
  • Mol. W.505.86 g/mol
  • Stock Status:Instock
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Levocetirizine EP Impurity G
Levocetirizine EP Impurity G
  • CAT. No.C100005A
  • CAS. No.682323-77-9
  • Mol. F.C23H29ClN2O4
  • Mol. W.432.94 g/mol
  • Stock Status:Instock
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Cetirizine EP Impurity F
Cetirizine EP Impurity F
  • CAT. No.C100006
  • CAS. No.83881-53-2
  • Mol. F.C21H26N2O3
  • Mol. W.354.44 g/mol
  • Stock Status:Instock
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Cetirizine Lactose Ester Hydrochloride (Mixture of alpha and beta Isomers)
Cetirizine Lactose Ester Hydrochloride (Mixture of alpha and beta Isomers)
  • CAT. No.C100007
  • CAS. No.NA
  • Mol. F.C33H45ClN2O13.HCl
  • Mol. W.749.63 g/mol
  • Stock Status:Under Synthesis
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Cetirizine Ethyl Ester Hydrochloride
Cetirizine Ethyl Ester Hydrochloride
  • CAT. No.C100008
  • CAS. No.246870-46-2 (free base)
  • Mol. F.C23H29ClN2O3.HCl
  • Mol. W.453.40 g/mol
  • Stock Status:Instock
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Cetirizine methyl ester
Cetirizine methyl ester
  • CAT. No.C100009
  • CAS. No.83881-46-3
  • Mol. F.C22H27ClN2O3
  • Mol. W.402.92 g/mol
  • Stock Status:Instock
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4-Chlorobenzophenone
4-Chlorobenzophenone
  • CAT. No.C100010
  • CAS. No.134-85-0
  • Mol. F.C13H9ClO
  • Mol. W.216.66 g/mol
  • Stock Status:Custom Synthesis
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4-Chlorobenzhydrol
4-Chlorobenzhydrol
  • CAT. No.C100011
  • CAS. No.119-56-2
  • Mol. F.C13H11ClO
  • Mol. W.218.66 g/mol
  • Stock Status:Under Synthesis
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Cetirizine N-Oxide
Cetirizine N-Oxide
  • CAT. No.C100013
  • CAS. No.1076199-80-8
  • Mol. F.C21H25ClN2O4
  • Mol. W.404.89 g/mol
  • Stock Status:Instock
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Cetirizine 3-Chloro Impurity Dihydrochloride
Cetirizine 3-Chloro Impurity Dihydrochloride
  • CAT. No.C100014
  • CAS. No.1232460-29-5
  • Mol. F.C21H25ClN2O3.2HCl
  • Mol. W.461.81 g/mol
  • Stock Status:Instock
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Cetirizine Glycerol ester Dihydrochloride
Cetirizine Glycerol ester Dihydrochloride
  • CAT. No.C100015
  • CAS. No.NA
  • Mol. F.C24H31ClN2O5.2HCl
  • Mol. W.535.89 g/mol
  • Stock Status:Limited Stock
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Cetirizine Glycerol Ester
Cetirizine Glycerol Ester
  • CAT. No.C100015A
  • CAS. No.1243652-36-9
  • Mol. F.C24H31ClN2O5
  • Mol. W.462.97 g/mol
  • Stock Status:Instock
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Propylene Glycol Ester Of Cetrizine (Mixture of Diastereomers)
Propylene Glycol Ester Of Cetrizine (Mixture of Diastereomers)
  • CAT. No.C100018
  • CAS. No.2705552-48-1
  • Mol. F.C24H31ClN2O4
  • Mol. W.446.97 g/mol
  • Stock Status:Instock
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(R)Cetirizine Propanediol Ester Impurity
(R)Cetirizine Propanediol Ester Impurity
  • CAT. No.C100018A
  • CAS. No.NA
  • Mol. F.C24H31ClN2O4
  • Mol. W.446.97 g/mol
  • Stock Status:Custom Synthesis
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Cetirizine Propanediol Ester Impurity Dihydrochloride
Cetirizine Propanediol Ester Impurity Dihydrochloride
  • CAT. No.C100018B
  • CAS. No.2705552-48-1 (free base)
  • Mol. F.C24H31ClN2O4.2HCl
  • Mol. W.519.89 g/mol
  • Stock Status:Instock
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N,N-Bis(2-chloroethyl)benzenesulfonamide
N,N-Bis(2-chloroethyl)benzenesulfonamide
  • CAT. No.C100020
  • CAS. No.58023-19-1
  • Mol. F.C10H13Cl2NO2S
  • Mol. W.282.19 g/mol
  • Stock Status:Instock
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Cetirizine Impurity 2
Cetirizine Impurity 2
  • CAT. No.C100021
  • CAS. No.1391052-52-0
  • Mol. F.C23H23ClN2O2S
  • Mol. W.426.96 g/mol
  • Stock Status:Instock
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Cetirizine 2-chloro hydrochloride
Cetirizine 2-chloro hydrochloride
  • CAT. No.C100023
  • CAS. No.4997-64-2(Freeacid)
  • Mol. F.C17H20Cl2N2
  • Mol. W.323.26 g/mol
  • Stock Status:Instock
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Cetirizine Deschloro Ethanol Impurity
Cetirizine Deschloro Ethanol Impurity
  • CAT. No.C100024
  • CAS. No.108983-83-1
  • Mol. F.C19H26Cl2N2O
  • Mol. W.369.33 g/mol
  • Stock Status:Instock
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Cetirizine Amide Impurity
Cetirizine Amide Impurity
  • CAT. No.C100027
  • CAS. No.83881-37-2
  • Mol. F.C21H26ClN3O2
  • Mol. W.387.90 g/mol
  • Stock Status:Instock
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Cetirizine Amide Dihydrochloride
Cetirizine Amide Dihydrochloride
  • CAT. No.C100027A
  • CAS. No.200707-85-3
  • Mol. F.C21H26ClN3O2.2HCl
  • Mol. W.460.82 g/mol
  • Stock Status:Instock
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Cetirizine EP Impurity G
Cetirizine EP Impurity G
  • CAT. No.C100028
  • CAS. No.109806-71-5
  • Mol. F.C19H23ClN2O
  • Mol. W.330.85 g/mol
  • Stock Status:Custom Synthesis
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(R)-De(carboxymethyl)Cetirizine Ethanol Dihydrochloride
(R)-De(carboxymethyl)Cetirizine Ethanol Dihydrochloride
  • CAT. No.C100028A
  • CAS. No.728948-88-7
  • Mol. F.C19H25Cl3N2O
  • Mol. W.403.77 g/mol
  • Stock Status:Instock
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Cetirizine Sorbitol Ester Impurity
Cetirizine Sorbitol Ester Impurity
  • CAT. No.C100029
  • CAS. No.13848888-64-5
  • Mol. F.C27H37ClN2O8
  • Mol. W.553.06 g/mol
  • Stock Status:Custom Synthesis
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Bromo Cetirizine Impurity
Bromo Cetirizine Impurity
  • CAT. No.C100030
  • CAS. No.NA
  • Mol. F.C21H25BrN2O3
  • Mol. W.433.30 g/mol
  • Stock Status:Instock
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Dichloro Cetrizine
Dichloro Cetrizine
  • CAT. No.C100031
  • CAS. No.NA
  • Mol. F.C21H24Cl2N2O3
  • Mol. W.423.30 g/mol
  • Stock Status:Instock
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1-((4-chlorophenyl)(phenyl)methyl)-4-(2-methoxyethyl)piperazine
1-((4-chlorophenyl)(phenyl)methyl)-4-(2-methoxyethyl)piperazine
  • CAT. No.C100032
  • CAS. No.NA
  • Mol. F.C20H25ClN2O
  • Mol. W.344.88 g/mol
  • Stock Status:Custom Synthesis
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2-(2-(piperazin-1-yl)ethoxy)acetic acid
2-(2-(piperazin-1-yl)ethoxy)acetic acid
  • CAT. No.C100033
  • CAS. No.NA
  • Mol. F.C8H16N2O3
  • Mol. W.188.22 g/mol
  • Stock Status:Custom Synthesis
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Isopropyl Ester of Cetirizine
Isopropyl Ester of Cetirizine
  • CAT. No.C100034
  • CAS. No.324047-27-0
  • Mol. F.C24H31ClN2O3
  • Mol. W.430.97 g/mol
  • Stock Status:Custom Synthesis
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Propylene Glycol Ester of Cetirizine Diastereomer 2
Propylene Glycol Ester of Cetirizine Diastereomer 2
  • CAT. No.C100035
  • CAS. No.NA
  • Mol. F.C24H31ClN2O4
  • Mol. W.476.95 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Hydroxyzine EP Impurity A
N-Nitroso Hydroxyzine EP Impurity A
  • CAT. No.C100037
  • CAS. No.2005-04-1
  • Mol. F.C17H18ClN3O
  • Mol. W.315.80 g/mol
  • Stock Status:Instock
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Cetirizine Impurity 5
Cetirizine Impurity 5
  • CAT. No.C100040
  • CAS. No.NA
  • Mol. F.C21H24Cl2N2O3
  • Mol. W.423.33 g/mol
  • Stock Status:Custom Synthesis
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1-butyl-4-((4-chlorophenyl)(phenyl)methyl)piperazine-2-one
1-butyl-4-((4-chlorophenyl)(phenyl)methyl)piperazine-2-one
  • CAT. No.C100042
  • CAS. No.NA
  • Mol. F.C21H25ClN2O
  • Mol. W.356.89 g/mol
  • Stock Status:Custom Synthesis
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2-chloro-2-(4-((4-chlorophenyl) (phenyl) methyl) piperazin-1-yl) acetic acid
2-chloro-2-(4-((4-chlorophenyl) (phenyl) methyl) piperazin-1-yl) acetic acid
  • CAT. No.C100043
  • CAS. No.NA
  • Mol. F.C19H20Cl2N2O2
  • Mol. W.379.28 g/mol
  • Stock Status:Custom Synthesis
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Cetirizine Methyl Ester Dihydrochloride
Cetirizine Methyl Ester Dihydrochloride
  • CAT. No.C100044
  • CAS. No.83881-48-5
  • Mol. F.C22H27ClN2O3.2HCl
  • Mol. W.475.84 g/mol
  • Stock Status:Custom Synthesis
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Levocetirizine Impurity 1
Levocetirizine Impurity 1
  • CAT. No.C100045
  • CAS. No.942193-17-1
  • Mol. F.C19H21ClN2O2
  • Mol. W.344.84 g/mol
  • Stock Status:Instock
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(S)-2-(4-((4-Chlorophenyl)(phenyl)methyl)piperazin-1-yl)acetic acid
(S)-2-(4-((4-Chlorophenyl)(phenyl)methyl)piperazin-1-yl)acetic acid
  • CAT. No.C100046
  • CAS. No.942193-18-2
  • Mol. F.C19H21ClN2O2
  • Mol. W.344.84 g/mol
  • Stock Status:Instock
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Cetirizine Related Compound A Oxalate
Cetirizine Related Compound A Oxalate
  • CAT. No.C100048
  • CAS. No.246870-46-2(free base)
  • Mol. F.C23H29ClN2O3.C2H2O4
  • Mol. W.506.98 g/mol
  • Stock Status:Instock
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Cetrizine Impurity 20
Cetrizine Impurity 20
  • CAT. No.C100049
  • CAS. No.439858-21-6
  • Mol. F.C17H19ClN2
  • Mol. W.286.80 g/mol
  • Stock Status:Custom Synthesis
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1-hydroxypropan-2-yl-2-(2-(4-((4-Chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)acetate.
1-hydroxypropan-2-yl-2-(2-(4-((4-Chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)acetate.
  • CAT. No.C100050
  • CAS. No.NA
  • Mol. F.C24H31ClN2O4
  • Mol. W.446.97 g/mol
  • Stock Status:Custom Synthesis
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Cetrizine Impurity 19
Cetrizine Impurity 19
  • CAT. No.C100051
  • CAS. No.NA
  • Mol. F.C23H30Cl2N2O2
  • Mol. W.437.40 g/mol
  • Stock Status:Custom Synthesis
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1-[2-(2-Chloro-ethoxy)-ethyl]-4-[(4-chloro-phenyl)-phenyl-methyl]-piperazine
1-[2-(2-Chloro-ethoxy)-ethyl]-4-[(4-chloro-phenyl)-phenyl-methyl]-piperazine
  • CAT. No.C100052
  • CAS. No.NA
  • Mol. F.C21H26Cl2N2O
  • Mol. W.393.35 g/mol
  • Stock Status:Custom Synthesis
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N,N-Bis(2-chlorophenyl)benzenesulfonamide
N,N-Bis(2-chlorophenyl)benzenesulfonamide
  • CAT. No.C100053
  • CAS. No.NA
  • Mol. F.C18H13Cl2NO2S
  • Mol. W.378.27 g/mol
  • Stock Status:Custom Synthesis
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Cetirizine Impurity 7
Cetirizine Impurity 7
  • CAT. No.C100054
  • CAS. No.82-93-9
  • Mol. F.C18H21ClN2
  • Mol. W.300.83 g/mol
  • Stock Status:Custom Synthesis
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Cetrizine-D-Mannitol Ester
Cetrizine-D-Mannitol Ester
  • CAT. No.C100055
  • CAS. No.NA
  • Mol. F.C27H37ClN2O8
  • Mol. W.553.00 g/mol
  • Stock Status:Custom Synthesis
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Cetirizine Impurity 16
Cetirizine Impurity 16
  • CAT. No.C100056
  • CAS. No.NA
  • Mol. F.C48H62Cl2N4O8
  • Mol. W.893.93 g/mol
  • Stock Status:Custom Synthesis
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Cetirizine Impurity 17
Cetirizine Impurity 17
  • CAT. No.C100057
  • CAS. No.NA
  • Mol. F.C48H62Cl2N4O8
  • Mol. W.893.93 g/mol
  • Stock Status:Custom Synthesis
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Levocetirizine Impurity 6 Dihydrochloride
Levocetirizine Impurity 6 Dihydrochloride
  • CAT. No.C100059
  • CAS. No.NA
  • Mol. F.C19H21ClN2O2.2HCl
  • Mol. W.417.76 g/mol
  • Stock Status:Instock
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Cetirizine Impurity 18
Cetirizine Impurity 18
  • CAT. No.C100060
  • CAS. No.NA
  • Mol. F.C22H27ClN2O3
  • Mol. W.402.91 g/mol
  • Stock Status:Custom Synthesis
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Cetrizine Impurity 24
Cetrizine Impurity 24
  • CAT. No.C100061
  • CAS. No.56961-47-8
  • Mol. F.C13H10Cl2
  • Mol. W.237.12 g/mol
  • Stock Status:Custom Synthesis
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Cetrizine Impurity 26
Cetrizine Impurity 26
  • CAT. No.C100062
  • CAS. No.13391-39-4
  • Mol. F.C13H10Cl2
  • Mol. W.237.12 g/mol
  • Stock Status:Custom Synthesis
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Cetirizine Dimer Impurity
Cetirizine Dimer Impurity
  • CAT. No.C100063
  • CAS. No.NA
  • Mol. F.C40H48Cl2N4O2
  • Mol. W.687.74 g/mol
  • Stock Status:Custom Synthesis
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Cetirizine Lactose Ester
Cetirizine Lactose Ester
  • CAT. No.C100064
  • CAS. No.NA
  • Mol. F.C33H45ClN2O13
  • Mol. W.713.17 g/mol
  • Stock Status:Custom Synthesis
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Ethoxy Cetirizine
Ethoxy Cetirizine
  • CAT. No.C100065
  • CAS. No.324047-29-2
  • Mol. F.C23H29ClN2O4
  • Mol. W.432.90 g/mol
  • Stock Status:Custom Synthesis
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Hydroxyzine Hydrochloride Impurity 1
Hydroxyzine Hydrochloride Impurity 1
  • CAT. No.C100066
  • CAS. No.NA
  • Mol. F.C28H39ClN2O6
  • Mol. W.535.07 g/mol
  • Stock Status:Custom Synthesis
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Propylene Glycol Ester of Cetirizine Diastereomer 1
Propylene Glycol Ester of Cetirizine Diastereomer 1
  • CAT. No.C100067
  • CAS. No.NA
  • Mol. F.C24H31ClN2O4
  • Mol. W.447.00 g/mol
  • Stock Status:Custom Synthesis
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Propylene Glycol Ester of Cetirizine Diastereomer 2
Propylene Glycol Ester of Cetirizine Diastereomer 2
  • CAT. No.C100068
  • CAS. No.NA
  • Mol. F.C24H31ClN2O4
  • Mol. W.447.00 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Chlorobenzhydryl Piperazine
N-Nitroso Chlorobenzhydryl Piperazine
  • CAT. No.C100069
  • CAS. No.NA
  • Mol. F.C17H18ClN3O
  • Mol. W.315.80 g/mol
  • Stock Status:Custom Synthesis
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Cetirizine Polyethylene Glycol Ester
Cetirizine Polyethylene Glycol Ester
  • CAT. No.C100070
  • CAS. No.1509941-93-8
  • Mol. F.C21H25ClN2O3(C2H4O)n
  • Mol. W.432.94 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Cetrizine Impurity 1
N-Nitroso Cetrizine Impurity 1
  • CAT. No.C100071
  • CAS. No.NA
  • Mol. F.C8H15N3O4
  • Mol. W.217.22 g/mol
  • Stock Status:Custom Synthesis
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Cetirizine Impurity 3
Cetirizine Impurity 3
  • CAT. No.C100072
  • CAS. No.83881-35-0
  • Mol. F.C21H27N3O2
  • Mol. W.353.50 g/mol
  • Stock Status:Custom Synthesis
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Cetirizine Ethyl Ester
Cetirizine Ethyl Ester
  • CAT. No.L040011
  • CAS. No.246870-46-2
  • Mol. F.C23H29ClN2O3
  • Mol. W.416.94 g/mol
  • Stock Status:Custom Synthesis
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Isotope Labelled Compounds

Cetirizine-d4
Cetirizine-d4
  • CAT. No.C100012
  • CAS. No.1219803-84-5
  • Mol. F.C21H21D4ClN2O3
  • Mol. W.392.89 g/mol
  • Stock Status:Custom Synthesis
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Cetirizine D8 Dihydrochloride
Cetirizine D8 Dihydrochloride
  • CAT. No.C100019
  • CAS. No.NA
  • Mol. F.C21H17D8ClN2O3.2HCl
  • Mol. W.496.26 g/mol
  • Stock Status:Instock
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R-Cetirizine D4 Dihydrochloride
R-Cetirizine D4 Dihydrochloride
  • CAT. No.C100022
  • CAS. No.NA
  • Mol. F.C21H21D4ClN2O3.2HCl
  • Mol. W.465.83 g/mol
  • Stock Status:Limited Stock
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N-Nitroso Cetirizine EP Impurity A D8
N-Nitroso Cetirizine EP Impurity A D8
  • CAT. No.C100058
  • CAS. No.NA
  • Mol. F.C17H10D8ClN3O
  • Mol. W.323.85 g/mol
  • Stock Status:Instock
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