Clopidogrel Hydrochloride Related Compounds & Impurities

Clopidogrel Hydrochloride is the hydrochloride salt of the irreversible P2Y12 antiplatelet agent, requiring its own pharmacopoeial specifications distinct from the bisulfate form.

Simson Pharma Limited along with its subsidiary offices Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) is a trusted manufacturer and supplier of high-quality pharmaceutical reference standards, offering a comprehensive portfolio of Clopidogrel Hydrochloride reference standards, pharmacopeial and non-pharmacopeial Clopidogrel Hydrochloride impurities, related compounds, related substances, metabolites, stable isotope-labelled compounds, deuterium labelled compounds and nitrosamine (N-NO) reference standards.

These materials support pharmaceutical research and development, product development, ANDA and DMF submissions, quality control (QC), analytical method development and validation, stability studies, impurity identification, and genotoxic impurity assessment.

Our Clopidogrel Hydrochloride-related reference standards are thoroughly characterized using advanced analytical techniques and are supplied with comprehensive Certificates of Analysis (COA) and supporting analytical data from our USFDA certified, ISO 17025 and ISO 17034 accredited Lab, to meet global regulatory expectations. EP and USP traceable reference standards can also be provided upon request, subject to availability. Simson is also a provider of EP and USP traceable standards. To ensure consistent quality and reliability, our reference standards are periodically re-tested according to established quality management procedures.

Pharmaceutical Reference Standards / Impurity Standards

Clopidogrel Sulfate
Clopidogrel Besylate
Clopidogrel Bisulphate Form II
Clopidogrel EP Impurity A Hydrochloride
Clopidogrel EP Impurity B
Clopidogrel Related Compound C
Clopidogrel Thienylthyl Impurity
Clopidogrel Impurity B
Clopidogrel Thieno Impurity Hydrochloride
Clopidogrel Pyridinium Bromide Impurity
Clopidogrel Related Compound B
Clopidogrel Related Compound B sulfate
Clopidogrel EP Impurity D
2-(2-Chlorophenyl)glycine
2-Thiopheneethanol
Benzenesulfonyl Chloride
Clopidogrel EP Impurity F
2-Oxo Clopidogrel Hydrochloride
2-Oxo Clopidogrel bisulfate
Clopidogrel Impurity B
Clopidogrel Amide R-Isomer
Clopidogrel EP Impurity E
Clopidogrel Amide Racemate
Clopidogrel Sulfonated Impurity
Clopidogrel Hydrogen Sulfate Racemate (Mixture of R & S isomer)
2-Oxo-Clopidogrel D4
2-(thiophen-3-yl)ethyl4-methylbenzenesulfonate
Clopidogrel Thiol Metabolite TFA salt
Clopidogrel Bisulfate Form-I
trans-Clopidogrel Thiol Metabolite (Mixture of Diastereomers)
Clopidogrel Nitroso Impurity
(S)-(+)-2-Chlorophenylglycine Methyl Ester Tartrate
Clopidogrel Oxidative Impurity F
Methyl2-(2-chlorophenyl)-2-(nitroso(2-(thiophen-2-yl)ethyl)amino)acetate
Methyl(R)-2-amino-2-(2-chlorophenyl)acetate Hydrochloride
(R)-methyl2-amino-2-(2-chlorophenyl)acetate 2,3-dihydroxysuccinate
(R)-methyl-2-(2-chlorophenyl)-2-((2-(thiophen-2-yl)ethyl)amino)acetate hydrochloride
5-(2-chlorobenzyl)thieno[3,2-c]pyridin-5-ium
Clopidogrel Impurity 30
Clopidogrel Impurity 34
6,7-dihydrothieno (3,2-c) pyridine
5-(1-(2-Chlorophenyl)-2-methoxy-2-oxoethyl)-6,7-dihydrothieno[3,2-c]pyridin-5-ium chloride
2,6,8-Trimethylnon-5-en-4-one
(S)-methyl2-amino-2-(3-chlorophenyl)acetate hydrochloride
S-Clopidogrel N-Methyl Impurity
Clopidogrel Impurity 26
Methyl 2-(bis(2-(thiophen-2-yl)ethyl)amino)-2-(2-chlorophenyl)acetate
5-(1-(4-chlorophenyl)-2-methoxy-2-oxoethyl)-4,5,6,7-tetrahydro thieno[3,2-c]pyridine 5-oxide
Clopidogrel EP Impurity B
(S)-methyl 2-(2-chlorophenyl)-2-(4,5-dihydrothieno[2,3-c]pyridin-6(7H)-yl)acetate Hydrogen sulphate
(S)-isopropyl 2-(2-chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate
N-Nitroso Clopidogrel EP Impurity F
Clopidogrel Impurity 5
3,4-Thiophenediethanol
Dimethyl2,2`-((thiophene-2,3-diylbis(ethane-2,1-diyl))bis(azanediyl))(2R,2`R)-bis(2-(2-chlorophenyl)acetate)
Dimethyl2,2`-((thiophene-3,4-diylbis(ethane-2,1-diyl))bis(azanediyl))(2R,2`R)-bis(2-(2-chlorophenyl)acetate)
2,4-Thiophenediethanol
Clopidogrel Impurity 40
3-chloro Clopidrogrel
Clopidogrel Impurity 25
4-Chloro Clopidogrel
Deschloro Clopidogrel
Methyl (S)-2-amino-2-phenylacetate hydrochloride
Clopidogrel Hydrochloride
5-[1-(2-Chlorophenyl)-2-methoxy-2-oxoethyl]thieno[3,2-c]pyridinium
2-(2-Chlorophenyl)-2-((2-(thiophen-2-yl)ethyl)amino)acetic acid hydrochloride
N-Methylene-2-(thiophen-2-yl)ethanamine
Methyl(2R)-(2-chlorophenyl)[4,7-dihydrothieno[2,3-c]pyridin-6(5H)-yl]acetate
Clopidogrel
Clopidogrel Pyridinium Bromide(S-isomer)
Clopidogrel Impurity 27
Clopidogrel Impurity 18
Cis-Clopidogrel-MP Derivative
Clopidogrel EP Impurity A
rac-Clopidogrel Carboxylic Acid Hydrochloride
Clopidogrel Impurity 49
Clopidogrel Impurity 50
Clopidogrel Impurity 51
Clopidogrel Impurity 52
Clopidogrel Impurity 35
Clopidogrel Impurity 35 Bromide
Clopidogrel Acid R-Isomer
Clopidogrel Impurity CHOX
Clopidogrel impurity 1
Clopidogrel Impurity 6
Clopidogrel Amide Impurity
Clopidogrel Acid N-Oxide
2-Oxo R-clopidogrel
Clopidogrel Impurity 7
Clopidogrel Impurity 2
Clopidogrel Impurity 3
Clopidogrel impurity 8
Clopidogrel Impurity 4
Rac-Clopidogrel Carboxylic Acid
Clopidogrel Impurity 11
Clopidogrel Impurity 13
Clopidogrel Impurity 10
methyl 2-amino-2-(2-chlorophenyl)acetate
Clopidogrel Impurity 9

Metabolites

Clopidogrel Acyl-beta-D-glucuronide
Clopidogrel Impurity 12
Clopidogrel camphorsulfonate
Clopidogrel Thiol Metabolite H4 Isomer formic acid
Clopidogrel Active Metabolite

Isotope Labelled Compounds

Clopidogrel-D4 Hydrogen Sulphate
Clopidogrel-d4 Carboxylic Acid
Clopidogrel-d3
Clopidogrel-D4 Hydrogensulfate
[13C6]-Clopidogrel Thiol Metabolite (mixture of diastereomers)
Clopidogrel Thiol Metabolite H4 Isomer-13C,D3
rac-Clopidogrel D3 Sulfate