Cobicistat Related Compounds & Impurities

Cobicistat is a selective CYP3A inhibitor used as a pharmacokinetic booster in fixed-dose HIV combination regimens without intrinsic antiviral activity of its own.

Simson Pharma Limited along with its subsidiary offices Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) is a trusted manufacturer and supplier of high-quality pharmaceutical reference standards, offering a comprehensive portfolio of Cobicistat reference standards, pharmacopeial and non-pharmacopeial Cobicistat impurities, related compounds, related substances, metabolites, stable isotope-labelled compounds, deuterium labelled compounds and nitrosamine (N-NO) reference standards.

These materials support pharmaceutical research and development, product development, ANDA and DMF submissions, quality control (QC), analytical method development and validation, stability studies, impurity identification, and genotoxic impurity assessment.

Our Cobicistat-related reference standards are thoroughly characterized using advanced analytical techniques and are supplied with comprehensive Certificates of Analysis (COA) and supporting analytical data from our USFDA certified, ISO 17025 and ISO 17034 accredited Lab, to meet global regulatory expectations. EP and USP traceable reference standards can also be provided upon request, subject to availability. Simson is also a provider of EP and USP traceable standards. To ensure consistent quality and reliability, our reference standards are periodically re-tested according to established quality management procedures.

Pharmaceutical Reference Standards / Impurity Standards

Cobicistat
(alphaS)-alpha-[[[Methyl[[2-(1-methylethyl)-4-thiazolyl]methyl]amino]carbonyl]amino]-4-morpholinebutanoic acid methyl ester
Cobicistat Impurity 10
N-[(1R,4R)-4-Amino-5-phenyl-1-(phenylmethyl)pentyl]carbamic acid 5-thiazolylmethyl ester hydrochloride
Bis(1,3-Thiazol-5-ylmethyl[(2R,5R)-5-amino-1,6-diphenylhexane-2-yl]bis carbamate
Cobicistat Thiazole Carbonate Impurity
Hydroxy Cobicistat
Cobicistat Impurity-2-Trihydrochloride
Cobicistat Impurity 11
Cobicistat Impurity 12
Cobicistat Impurity 1
Cobicistat Impurity 8
Cobicistat Impurity 9
Cobicistat Urea Impurity
Cobicistat SSS Isomer
Cobicistat RRR Isomer
Cobicistat(S,S,R) Isomer
Cobicistat Impurity 13
Cobicistat Impurity 2
Morpholine N-Oxide Impurity
Morpholine Amine Impurity
Dithiazole Diamine Impurity
Cobicistat Impurity 3
Cobicistat Impurity 4
Dithiazole Carbonate Impurity
Cobicistat Impurity 5
Cobicistat Impurity 6
Cobicistat Impurity 7
Cobicistat (S,R,S) Isomer
Cobicistat 2-Amino Amide Impurity
Cobicistat Impurity 14
Cobicistat Impurity 15
Cobicistat Impurity 16

Isotope Labelled Compounds

Cobicistat D8