Cyclophosphamide Related Compounds & Impurities

Cyclophosphamide is an oxazaphosphorine nitrogen-mustard alkylating agent bioactivated by hepatic CYP2B6 to phosphoramide mustard, used across haematological malignancies, solid tumours and as an immunosuppressant for autoimmune diseases.

Simson Pharma Limited along with its subsidiary offices Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) is a trusted manufacturer and supplier of high-quality pharmaceutical reference standards, offering a comprehensive portfolio of Cyclophosphamide reference standards, pharmacopeial and non-pharmacopeial Cyclophosphamide impurities, related compounds, related substances, metabolites, stable isotope-labelled compounds, deuterium labelled compounds and nitrosamine (N-NO) reference standards.

These materials support pharmaceutical research and development, product development, ANDA and DMF submissions, quality control (QC), analytical method development and validation, stability studies, impurity identification, and genotoxic impurity assessment.

Our Cyclophosphamide-related reference standards are thoroughly characterized using advanced analytical techniques and are supplied with comprehensive Certificates of Analysis (COA) and supporting analytical data from our USFDA certified, ISO 17025 and ISO 17034 accredited Lab, to meet global regulatory expectations. EP and USP traceable reference standards can also be provided upon request, subject to availability. Simson is also a provider of EP and USP traceable standards. To ensure consistent quality and reliability, our reference standards are periodically re-tested according to established quality management procedures.

Pharmaceutical Reference Standards / Impurity Standards

Cyclophosphamide monohydrate
Cyclophosphamide monohydrate
  • CAT. No.C1010000
  • CAS. No.6055-19-2
  • Mol. F.C7H15Cl2N2O2P.H2O
  • Mol. W.279.10 g/mol
  • Stock Status:Instock
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Cyclophosphamide RC A
Cyclophosphamide RC A
  • CAT. No.C1010001
  • CAS. No.821-48-7
  • Mol. F.C4H10Cl3N
  • Mol. W.178.49 g/mol
  • Stock Status:Instock
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Cyclophosphamide EP Impurity D
Cyclophosphamide EP Impurity D
  • CAT. No.C1010002
  • CAS. No.158401-52-6
  • Mol. F.C8H17Cl2N2O2P
  • Mol. W.275.11 g/mol
  • Stock Status:Limited Stock
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Cyclophosphamide EP Impurity F
Cyclophosphamide EP Impurity F
  • CAT. No.C1010003
  • CAS. No.1071-28-9
  • Mol. F.C3H10NO4P
  • Mol. W.155.09 g/mol
  • Stock Status:Instock
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Cyclophosphamide Related Compound D
Cyclophosphamide Related Compound D
  • CAT. No.C1010004
  • CAS. No.158401-51-5
  • Mol. F.C7H18ClN2O4P.2HCl
  • Mol. W.333.58 g/mol
  • Stock Status:Instock
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Cyclophosphamide EP Impurity B
Cyclophosphamide EP Impurity B
  • CAT. No.C1010005
  • CAS. No.22089-17-4
  • Mol. F.C8H17Cl2N2O2P
  • Mol. W.275.11 g/mol
  • Stock Status:Instock
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Cyclophosphamide Impurity 13
Cyclophosphamide Impurity 13
  • CAT. No.C1010006
  • CAS. No.127-88-8
  • Mol. F.C4H8Cl4NOP
  • Mol. W.258.89 g/mol
  • Stock Status:Custom Synthesis
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Dexpanthenol EP Impurity A
Dexpanthenol EP Impurity A
  • CAT. No.C1010008
  • CAS. No.156-87-6
  • Mol. F.C3H9NO
  • Mol. W.75.11 g/mol
  • Stock Status:Instock
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2-((2-chloroethyl)amino)ethanol
2-((2-chloroethyl)amino)ethanol
  • CAT. No.C1010009
  • CAS. No.3890-98-0;2576-29-6(acid)
  • Mol. F.C4H10ClNO
  • Mol. W.123.58 g/mol
  • Stock Status:Custom Synthesis
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2-((2-Chloroethyl)amino)ethanol Hydrochloride
2-((2-Chloroethyl)amino)ethanol Hydrochloride
  • CAT. No.C1010009A
  • CAS. No.2576-29-6
  • Mol. F.C4H11Cl2NO
  • Mol. W.160.04 g/mol
  • Stock Status:Instock
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Alcophosphamide
Alcophosphamide
  • CAT. No.C1010010
  • CAS. No.52336-54-6
  • Mol. F.C7H17Cl2N2O3P
  • Mol. W.279.1 g/mol
  • Stock Status:Instock
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Cyclophosphamide EP Impurity A
Cyclophosphamide EP Impurity A
  • CAT. No.C1010011
  • CAS. No.1797009-12-1
  • Mol. F.C7H16ClN2O3P
  • Mol. W.242.64 g/mol
  • Stock Status:Under Synthesis
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Cyclophosphamide Impurity 6
Cyclophosphamide Impurity 6
  • CAT. No.C1010012
  • CAS. No.NA
  • Mol. F.C13H29N2O9P
  • Mol. W.388.35 g/mol
  • Stock Status:Custom Synthesis
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Cyclophosphamide Impurity 7
Cyclophosphamide Impurity 7
  • CAT. No.C1010013
  • CAS. No.NA
  • Mol. F.C13H30ClN2O9P
  • Mol. W.424.81 g/mol
  • Stock Status:Custom Synthesis
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Didechlorodihydroxycyclophosphamide
Didechlorodihydroxycyclophosphamide
  • CAT. No.C1010014
  • CAS. No.90632-33-0
  • Mol. F.C7H17N2O4P
  • Mol. W.224.19 g/mol
  • Stock Status:Instock
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Cyclophosphamide Pyrophosphate Analog
Cyclophosphamide Pyrophosphate Analog
  • CAT. No.C1010016
  • CAS. No.NA
  • Mol. F.C10H26ClN3O7P2
  • Mol. W.397.70 g/mol
  • Stock Status:Custom Synthesis
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Cyclophosphamide Impurity 1
Cyclophosphamide Impurity 1
  • CAT. No.C1010017
  • CAS. No.NA
  • Mol. F.C7H17N2O3P
  • Mol. W.208.20 g/mol
  • Stock Status:Custom Synthesis
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Cyclophosphamide Impurity 4
Cyclophosphamide Impurity 4
  • CAT. No.C1010019
  • CAS. No.1566-15-0
  • Mol. F.C4H11Cl2N2O2P. C6H13N
  • Mol. W.320.20 g/mol
  • Stock Status:Instock
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Cyclophosphamide Impurity 5
Cyclophosphamide Impurity 5
  • CAT. No.C1010020
  • CAS. No.NA
  • Mol. F.C9H21N2O4P
  • Mol. W.252.25 g/mol
  • Stock Status:Custom Synthesis
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Cyclophosphamide Impurity 9
Cyclophosphamide Impurity 9
  • CAT. No.C1010021
  • CAS. No.NA
  • Mol. F.C9H22ClN2O4P
  • Mol. W.288.71 g/mol
  • Stock Status:Custom Synthesis
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Cyclophosphamide Impurity 16
Cyclophosphamide Impurity 16
  • CAT. No.C1010022
  • CAS. No.1361416-62-7
  • Mol. F.C5H14NO4P
  • Mol. W.183.10 g/mol
  • Stock Status:Custom Synthesis
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Cyclophosphamide Related Compound F
Cyclophosphamide Related Compound F
  • CAT. No.C1010024
  • CAS. No.2387771-96-0
  • Mol. F.C9H20ClN2O3P
  • Mol. W.270.69 g/mol
  • Stock Status:Under Synthesis
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Aldophosphamide
Aldophosphamide
  • CAT. No.C1010025
  • CAS. No.35144-64-0
  • Mol. F.C7H15Cl2N2O3P
  • Mol. W.277.09 g/mol
  • Stock Status:Custom Synthesis
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Cyclophosphamide Open Ring Ethanol Adduct
Cyclophosphamide Open Ring Ethanol Adduct
  • CAT. No.C1010026
  • CAS. No.3308-51-8
  • Mol. F.C7H17Cl2N2O3P
  • Mol. W.279.10 g/mol
  • Stock Status:Under Synthesis
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Cyclophosphamide Impurity 2 Hydrochloride
Cyclophosphamide Impurity 2 Hydrochloride
  • CAT. No.C1010027
  • CAS. No.2387771-95-9 (free base)
  • Mol. F.C9H23Cl2N2O4P
  • Mol. W.325.17 g/mol
  • Stock Status:Custom Synthesis
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Cyclophosphamide Oxide
Cyclophosphamide Oxide
  • CAT. No.C1010028
  • CAS. No.NA
  • Mol. F.C8H19N2O2P
  • Mol. W.206.22 g/mol
  • Stock Status:Instock
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N-(2-Chloroethyl)-3-hydroxypropylamine Hydrochloride
N-(2-Chloroethyl)-3-hydroxypropylamine Hydrochloride
  • CAT. No.C1010029
  • CAS. No.40722-80-3
  • Mol. F.C5H12ClNO.HCl
  • Mol. W.174.07 g/mol
  • Stock Status:Custom Synthesis
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N-(2-Chloroethyl)-3-hydroxypropylamine
N-(2-Chloroethyl)-3-hydroxypropylamine
  • CAT. No.C1010030
  • CAS. No.40722-99-1
  • Mol. F.C5H12ClNO
  • Mol. W.137.61 g/mol
  • Stock Status:Custom Synthesis
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Cyclophosphamide Impurity 12
Cyclophosphamide Impurity 12
  • CAT. No.C1010031
  • CAS. No.60106-92-5
  • Mol. F.C8H16Cl5N2OP
  • Mol. W.364.50 g/mol
  • Stock Status:Custom Synthesis
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Cyclophosphamide Related Compound B Trifluoroacetic acid
Cyclophosphamide Related Compound B Trifluoroacetic acid
  • CAT. No.C1010032
  • CAS. No.NA
  • Mol. F.C12H25ClF3N2O5P
  • Mol. W.400.76 g/mol
  • Stock Status:Custom Synthesis
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3-aminopropyl ethyl hydrogen phosphate Hydrochloride
3-aminopropyl ethyl hydrogen phosphate Hydrochloride
  • CAT. No.C1010033
  • CAS. No.NA
  • Mol. F.C5H15ClNO4P
  • Mol. W.219.04 g/mol
  • Stock Status:Custom Synthesis
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Cyclophosphamide Impurity 18
Cyclophosphamide Impurity 18
  • CAT. No.C1010034
  • CAS. No.NA
  • Mol. F.C9H22ClN2O4P
  • Mol. W.288.71 g/mol
  • Stock Status:Under Synthesis
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Cyclophosphamide
Cyclophosphamide
  • CAT. No.C1010035
  • CAS. No.50-18-0
  • Mol. F.C7H15Cl2N2O2P
  • Mol. W.261.09 g/mol
  • Stock Status:Instock
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Cyclophosphamide Chlorodiazinonyl Pentahydroxyhexyl Phosphate Dihydrochloride
Cyclophosphamide Chlorodiazinonyl Pentahydroxyhexyl Phosphate Dihydrochloride
  • CAT. No.C1010036
  • CAS. No.NA
  • Mol. F.C13H32Cl3N2O9P
  • Mol. W.497.73 g/mol
  • Stock Status:Custom Synthesis
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Cyclophosphamide Impurity 8
Cyclophosphamide Impurity 8
  • CAT. No.C1010037
  • CAS. No.2810251-24-0
  • Mol. F.C7H18ClN2O4P
  • Mol. W.260.66 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Cyclophosphamide
N-Nitroso Cyclophosphamide
  • CAT. No.C1010038
  • CAS. No.NA
  • Mol. F.C7H14Cl2N3O3P
  • Mol. W.290.08 g/mol
  • Stock Status:Custom Synthesis
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Cyclophosphamide Nitroso Impurity 1
Cyclophosphamide Nitroso Impurity 1
  • CAT. No.C1010039
  • CAS. No.NA
  • Mol. F.C7H16ClN4O6P
  • Mol. W.318.65 g/mol
  • Stock Status:Instock
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Cyclophosphamide Nitroso Impurity 2
Cyclophosphamide Nitroso Impurity 2
  • CAT. No.C1010040
  • CAS. No.NA
  • Mol. F.C7H17ClN3O5P
  • Mol. W.289.65 g/mol
  • Stock Status:Custom Synthesis
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Cyclophosphamide Nitroso Impurity 3
Cyclophosphamide Nitroso Impurity 3
  • CAT. No.C1010041
  • CAS. No.NA
  • Mol. F.C7H17ClN3O5P
  • Mol. W.289.65 g/mol
  • Stock Status:Custom Synthesis
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Cyclophosphamide Impurity 20
Cyclophosphamide Impurity 20
  • CAT. No.C1010042
  • CAS. No.NA
  • Mol. F.C9H21Cl2N2O3P
  • Mol. W.307.15 g/mol
  • Stock Status:Custom Synthesis
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Cyclophosphamide Impurity 21
Cyclophosphamide Impurity 21
  • CAT. No.C1010043
  • CAS. No.NA
  • Mol. F.C9H21Cl2N2O3P
  • Mol. W.307.15 g/mol
  • Stock Status:Custom Synthesis
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Cyclophosphamide Impurity 22
Cyclophosphamide Impurity 22
  • CAT. No.C1010044
  • CAS. No.NA
  • Mol. F.C9H18Cl2NO4P
  • Mol. W.306.12 g/mol
  • Stock Status:Custom Synthesis
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3-(2-chloroethyl)-2-hydroxy-6-nitroso-1,3,6,2-oxadiazaphosphonane 2-oxide
3-(2-chloroethyl)-2-hydroxy-6-nitroso-1,3,6,2-oxadiazaphosphonane 2-oxide
  • CAT. No.C1010045
  • CAS. No.NA
  • Mol. F.C7H15ClN3O4P
  • Mol. W.271.64 g/mol
  • Stock Status:Custom Synthesis
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N-Dechloroethyl Cyclophosphamide
N-Dechloroethyl Cyclophosphamide
  • CAT. No.C1010047
  • CAS. No.36761-83-8
  • Mol. F.C5H12ClN2O2P
  • Mol. W.198.59 g/mol
  • Stock Status:Instock
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Cyclophosphamide Impurity 23
Cyclophosphamide Impurity 23
  • CAT. No.C1010050
  • CAS. No.2387771-94-8
  • Mol. F.C9H21N2O4P
  • Mol. W.252.25 g/mol
  • Stock Status:Custom Synthesis
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Cyclophosphamide Impurity 24
Cyclophosphamide Impurity 24
  • CAT. No.C1010051
  • CAS. No.NA
  • Mol. F.C9H20ClN2O3P
  • Mol. W.270.69 g/mol
  • Stock Status:Custom Synthesis
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Cyclophosphamide Impurity 25
Cyclophosphamide Impurity 25
  • CAT. No.C1010052
  • CAS. No.53905-39-8
  • Mol. F.C9H21N2O4P
  • Mol. W.252.25 g/mol
  • Stock Status:Custom Synthesis
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Cyclophosphamide Ring Open Dimer impurity
Cyclophosphamide Ring Open Dimer impurity
  • CAT. No.C1010053
  • CAS. No.NA
  • Mol. F.C14H35Cl2N5O6P2
  • Mol. W.502.31 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Cyclophosphamide Hydrate
N-Nitroso Cyclophosphamide Hydrate
  • CAT. No.C1010054
  • CAS. No.NA
  • Mol. F.C7H14Cl2N3O3P.H2O
  • Mol. W.307.03 g/mol
  • Stock Status:Custom Synthesis
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Cyclophosphamide Impurity 26
Cyclophosphamide Impurity 26
  • CAT. No.C1010055
  • CAS. No.NA
  • Mol. F.C6H12ClN2O3P
  • Mol. W.226.60 g/mol
  • Stock Status:Custom Synthesis
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Cyclophosphamide Impurity 28
Cyclophosphamide Impurity 28
  • CAT. No.C1010056
  • CAS. No.2924754-60-7
  • Mol. F.C9H22ClN2O4P
  • Mol. W.288.71 g/mol
  • Stock Status:Custom Synthesis
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Cyclophosphamide Impurity 15
Cyclophosphamide Impurity 15
  • CAT. No.C1010057
  • CAS. No.NA
  • Mol. F.C9H20ClN2O4P
  • Mol. W.286.69 g/mol
  • Stock Status:Custom Synthesis
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Cyclophosphamide Impurity 3
Cyclophosphamide Impurity 3
  • CAT. No.C1010058
  • CAS. No.NA
  • Mol. F.C9H22ClN2O4P
  • Mol. W.288.71 g/mol
  • Stock Status:Custom Synthesis
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Cyclophosphamide Open Ring Polyethylene Glycol Adduct
Cyclophosphamide Open Ring Polyethylene Glycol Adduct
  • CAT. No.C1010059
  • CAS. No.NA
  • Mol. F.C8H19O8P
  • Mol. W.274.21 g/mol
  • Stock Status:Custom Synthesis
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Cyclophosphamide Impurity 10
Cyclophosphamide Impurity 10
  • CAT. No.C1010060
  • CAS. No.334-22-5
  • Mol. F.C4H9Cl2N
  • Mol. W.142.03 g/mol
  • Stock Status:Custom Synthesis
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Metabolites

Phosphoramide Mustard Cyclohexylamine Salt
Phosphoramide Mustard Cyclohexylamine Salt
  • CAT. No.C1010048
  • CAS. No.1566-15-00
  • Mol. F.C4H11Cl2N2O2P.C6H13N
  • Mol. W.320.20 g/mol
  • Stock Status:Custom Synthesis
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Isotope Labelled Compounds

Cyclophosphamide-D8
Cyclophosphamide-D8
  • CAT. No.C1010007
  • CAS. No.1178903-96-2
  • Mol. F.C7H7D8Cl2N2O2P
  • Mol. W.269.14 g/mol
  • Stock Status:Under Synthesis
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[2H8]-Cyclophosphamide Monohydrate
[2H8]-Cyclophosphamide Monohydrate
  • CAT. No.C1010046
  • CAS. No.NA
  • Mol. F.C7H9D8Cl2N2O3P
  • Mol. W.287.15 g/mol
  • Stock Status:Custom Synthesis
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