Canagliflozin Related Compounds & Impurities

Canagliflozin is a selective SGLT2 inhibitor with demonstrated cardiovascular and renoprotective benefits, approved for type 2 diabetes and heart failure.

Simson Pharma Limited along with its subsidiary offices Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) is a trusted manufacturer and supplier of high-quality pharmaceutical reference standards, offering a comprehensive portfolio of Canagliflozin reference standards, pharmacopeial and non-pharmacopeial Canagliflozin impurities, related compounds, related substances, metabolites, stable isotope-labelled compounds, deuterium labelled compounds and nitrosamine (N-NO) reference standards.

These materials support pharmaceutical research and development, product development, ANDA and DMF submissions, quality control (QC), analytical method development and validation, stability studies, impurity identification, and genotoxic impurity assessment.

Our Canagliflozin-related reference standards are thoroughly characterized using advanced analytical techniques and are supplied with comprehensive Certificates of Analysis (COA) and supporting analytical data from our USFDA certified, ISO 17025 and ISO 17034 accredited Lab, to meet global regulatory expectations. EP and USP traceable reference standards can also be provided upon request, subject to availability. Simson is also a provider of EP and USP traceable standards. To ensure consistent quality and reliability, our reference standards are periodically re-tested according to established quality management procedures.

Pharmaceutical Reference Standards / Impurity Standards

Canagliflozin Hemihydrate
Canagliflozin Enantiomer Impurity
Monoacetyl Canagliflozin
D-Glucono-1,5-lactone
3-(4-fluorophenyl) thiophene
Canagliflozin Impurity 31
2-(4-fluorophenyl) thiophene
Canagliflozin furanose Impurity
Canagliflozin Ring Opening Impurity
(R)-Canagliflozin Furanose Impurity
Canagliflozin Bromo Impurity
Canagliflozin Alpha Isomer
Canagliflozin Impurity 2
Canagliflozin Impurity 3
De-alpha-D-glucopyranoside Canagliflozin Dimer
(5-(4-fluorophenyl)thiophen-2-yl)(5-iodo-2-methylphenyl)methanol
Canagliflozin Desfluoro Impurity
Canagliflozin peroxide
Canagliflozin Impurity 1
Canagliflozin Tetraacetate
Canagliflozin Des-Iodo Impurity
Canagliflozin dimer Impurity 1
Canagliflozin Impurity 6
Canagliflozin Peroxide Impurity
Canagliflozin Impurity 39
Cangliflozin Impurity 7
Canagliflozin Impurity 4
Canagliflozin Impurity 4
Canagliflozin Impurity 8
Canagliflozin Acetyl Impurity
Canagliflozin 2-Methyl Impurity
Canagliflozin Iodo Impurity
Canagliflozin Hydroxy Impurity
Canagliflozin Impurity 15
Canagliflozin Impurity 7
Canagliflozin Dimer Impurity
Canagliflozin Impurity 16
Canagliflozin Impurity 17
Canagliflozin Impurity 18
Canagliflozin Furanose
Canagliflozin Impurity 19
2-(5-Bromo-2-methylbenzoyl)-5-(4-fluorophenyl)thiophene
1,4-bis(5-(5-bromo-2-methylbenzyl)thiophen-2-yl)benzene
Canagliflozin Furanose Impurity (mixture Of Anomers)
(3R,4S,5S,6R)-2-(3-((5-(4-Fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol
Alpha-D-Glucopyranose,1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-2,3,4,6-tetrakis-O-(trimethylsilyl)
Hexitol acetyl Impurity
Canagliflozin Impurity 32
2,3,4,6-tetra-O-acetyl-1-C-(3-{[5-(4-fluorophenyl)thiophen-2-yl]methyl}-4-methylphenyl)-D-glucopyranose
2-Phenylthiophene
1-(3-((5-(4-fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)hexane-1,2,3,4,5,6-hexaol
Canagliflozin Sulfone
Canagliflozin Impurity 5
3-((5-(4-fluorophenyl)thiophen-2-yl)methyl)-4-methylphenol
(2S,3R,4R,5R)-1-(4-((5-(4-fluorophenyl)thiophen-2-yl)methyl)-3-methylphenyl)hexane-1,2,3,4,5,6-hexaol
Canagliflozin
Canagliflozin Sulfoxide
Canagliflozin Impurity 45
Canagliflozin Impurity 46
D -Glucoheptono-1,4-lactone
Canagliflozin Impurity 47
Canagliflozin Impurity 48
Canagliflozin Impurity 34
Canagliflozin Dimer Impurity 2
Canagliflozin Impurity 35
Canagliflozin Impurity 36
Canagliflozin Furanose Mixture (R,S Isomer)
Canagliflozin Mono Hydrate
Canagliflozin Impurity 37
Canagliflozin Impurity 10
Canagliflozin Impurity 9
Canagliflozin Impurity 12
Canagliflozin Impurity 13
Canagliflozin Impurity 14
Canagliflozin Impurity 15
Landiolol Impurity 5

Metabolites

Canagliflozin-3-O-Beta-D-glucuronide

Isotope Labelled Compounds

Canagliflozin-D4