Cabozantinib Related Compounds & Impurities

Cabozantinib is a multi-target kinase inhibitor blocking MET, VEGFR, AXL and RET, used for advanced renal cell, hepatocellular and thyroid cancers.

Simson Pharma Limited along with its subsidiary offices Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) is a trusted manufacturer and supplier of high-quality pharmaceutical reference standards, offering a comprehensive portfolio of Cabozantinib reference standards, pharmacopeial and non-pharmacopeial Cabozantinib impurities, related compounds, related substances, metabolites, stable isotope-labelled compounds, deuterium labelled compounds and nitrosamine (N-NO) reference standards.

These materials support pharmaceutical research and development, product development, ANDA and DMF submissions, quality control (QC), analytical method development and validation, stability studies, impurity identification, and genotoxic impurity assessment.

Our Cabozantinib-related reference standards are thoroughly characterized using advanced analytical techniques and are supplied with comprehensive Certificates of Analysis (COA) and supporting analytical data from our USFDA certified, ISO 17025 and ISO 17034 accredited Lab, to meet global regulatory expectations. EP and USP traceable reference standards can also be provided upon request, subject to availability. Simson is also a provider of EP and USP traceable standards. To ensure consistent quality and reliability, our reference standards are periodically re-tested according to established quality management procedures.

Pharmaceutical Reference Standards / Impurity Standards

Cabozantinib
Cabozantinib
  • CAT. No.C1970000
  • CAS. No.849217-68-1
  • Mol. F.C28H24FN3O5
  • Mol. W.501.51 g/mol
  • Stock Status:Instock
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Cabozantinib S Malate
Cabozantinib S Malate
  • CAT. No.C1970000A
  • CAS. No.1140909-48-3
  • Mol. F.C28H24FN3O5.C4H6O5
  • Mol. W.635.59 g/mol
  • Stock Status:Instock
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Tivozanib Impurity 2
Tivozanib Impurity 2
  • CAT. No.C1970002
  • CAS. No.205448-31-3
  • Mol. F.C10H8ClNO2
  • Mol. W.209.62 g/mol
  • Stock Status:Custom Synthesis
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4-chloro-7-methoxyquinolin-6-ol
4-chloro-7-methoxyquinolin-6-ol
  • CAT. No.C1970003
  • CAS. No.205448-74-4
  • Mol. F.C10H8ClNO2
  • Mol. W.209.63 g/mol
  • Stock Status:Custom Synthesis
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Cabozantinib Impurity 2
Cabozantinib Impurity 2
  • CAT. No.C1970004
  • CAS. No.190728-24-6
  • Mol. F.C17H14N2O5
  • Mol. W.326.30 g/mol
  • Stock Status:Instock
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Cabozantinib Quinol Impurity
Cabozantinib Quinol Impurity
  • CAT. No.C1970005
  • CAS. No.13425-93-9
  • Mol. F.C11H11NO3
  • Mol. W.205.21 g/mol
  • Stock Status:Custom Synthesis
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Cabozantinib Desfluoro Impurity
Cabozantinib Desfluoro Impurity
  • CAT. No.C1970006
  • CAS. No.849221-94-9
  • Mol. F.C28H25N3O5
  • Mol. W.483.52 g/mol
  • Stock Status:Custom Synthesis
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Cabozantinib 3 fluoro Impurity
Cabozantinib 3 fluoro Impurity
  • CAT. No.C1970007
  • CAS. No.NA
  • Mol. F.C28H24FN3O5
  • Mol. W.501.51 g/mol
  • Stock Status:Custom Synthesis
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Cabozantinib Impurity 7
Cabozantinib Impurity 7
  • CAT. No.C1970008
  • CAS. No.NA
  • Mol. F.C28H24FN3O5
  • Mol. W.501.51 g/mol
  • Stock Status:Custom Synthesis
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Cabozantinib (s) Malate
Cabozantinib (s) Malate
  • CAT. No.C1970009
  • CAS. No.1140909-48-3
  • Mol. F.C32H30FN3O10
  • Mol. W.635.59 g/mol
  • Stock Status:Instock
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N1,N2-Bis(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)oxalamide
N1,N2-Bis(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)oxalamide
  • CAT. No.C1970014
  • CAS. No.NA
  • Mol. F.C36H30N4O8
  • Mol. W.646.65 g/mol
  • Stock Status:Instock
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Cabozantinib Impurity 9
Cabozantinib Impurity 9
  • CAT. No.C1970015
  • CAS. No.849217-48-7
  • Mol. F.C11H10NO3F
  • Mol. W.223.20 g/mol
  • Stock Status:Instock
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Cabozantinib Hydroxy Impurity
Cabozantinib Hydroxy Impurity
  • CAT. No.C1970016
  • CAS. No.849217-60-3
  • Mol. F.C17H15FN2O3
  • Mol. W.314.31 g/mol
  • Stock Status:Instock
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Cabozantinib Carboxylic Acid
Cabozantinib Carboxylic Acid
  • CAT. No.C1970017
  • CAS. No.849217-77-2
  • Mol. F.C22H20N2O6
  • Mol. W.408.40 g/mol
  • Stock Status:Instock
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Cabozantinib N-oxide
Cabozantinib N-oxide
  • CAT. No.C1970018
  • CAS. No.1621681-63-7
  • Mol. F.C28H24FN3O6
  • Mol. W.517.51 g/mol
  • Stock Status:Instock
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Cabozantinib Impurity 6
Cabozantinib Impurity 6
  • CAT. No.C1970019
  • CAS. No.NA
  • Mol. F.C28H25N3O5
  • Mol. W.483.52 g/mol
  • Stock Status:Instock
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Cabozantinib Impurity 20
Cabozantinib Impurity 20
  • CAT. No.C1970020
  • CAS. No.1345847-71-3
  • Mol. F.C12H12FNO3
  • Mol. W.237.23 g/mol
  • Stock Status:Custom Synthesis
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Cabozantinib Impurity 19
Cabozantinib Impurity 19
  • CAT. No.C1970021
  • CAS. No.2840522-81-6
  • Mol. F.C35H30N4O7
  • Mol. W.618.64 g/mol
  • Stock Status:Custom Synthesis
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((2S)-4-(4-((4-((6,7-Dimethoxyquinoline-4-yl)oxy)phenyl)amino)-3-((4-fluorophenyl)carbamoyl)-4-oxobutoxy)-2-hydroxy-4-oxobutanoic acid)
((2S)-4-(4-((4-((6,7-Dimethoxyquinoline-4-yl)oxy)phenyl)amino)-3-((4-fluorophenyl)carbamoyl)-4-oxobutoxy)-2-hydroxy-4-oxobutanoic acid)
  • CAT. No.C1970022
  • CAS. No.NA
  • Mol. F.C32H30FN3O10
  • Mol. W.635.59 g/mol
  • Stock Status:Custom Synthesis
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Cabozantinib Impurity 36
Cabozantinib Impurity 36
  • CAT. No.C1970023
  • CAS. No.NA
  • Mol. F.C28H24FN3O5
  • Mol. W.501.51 g/mol
  • Stock Status:Custom Synthesis
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N-(4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl)-N`-(4-fluorophenyl)-2-(2-hydroxyethyl)propanediamide
N-(4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl)-N`-(4-fluorophenyl)-2-(2-hydroxyethyl)propanediamide
  • CAT. No.C1970024
  • CAS. No.NA
  • Mol. F.C28H26FN3O6
  • Mol. W.519.52 g/mol
  • Stock Status:Custom Synthesis
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Cabozantinib impurity 23
Cabozantinib impurity 23
  • CAT. No.C1970025
  • CAS. No.NA
  • Mol. F.C32H30FN3O10
  • Mol. W.635.59 g/mol
  • Stock Status:Custom Synthesis
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Cabozantinib Impurity 22
Cabozantinib Impurity 22
  • CAT. No.C1970026
  • CAS. No.NA
  • Mol. F.C56H49F2N6O10
  • Mol. W.1004.02 g/mol
  • Stock Status:Custom Synthesis
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Cabozantinib Impurity 16
Cabozantinib Impurity 16
  • CAT. No.C1970027
  • CAS. No.2439164-91-5
  • Mol. F.C39H34N4O8
  • Mol. W.686.72 g/mol
  • Stock Status:Custom Synthesis
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Cabozantinib Impurity 25
Cabozantinib Impurity 25
  • CAT. No.C1970028
  • CAS. No.918642-61-2
  • Mol. F.C11H10FNO3
  • Mol. W.223.20 g/mol
  • Stock Status:Custom Synthesis
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Cabozantinib Chloro Impurity
Cabozantinib Chloro Impurity
  • CAT. No.C1970029
  • CAS. No.NA
  • Mol. F.C28H24ClN3O5
  • Mol. W.518.00 g/mol
  • Stock Status:Custom Synthesis
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Cabozantinib Impurity 27
Cabozantinib Impurity 27
  • CAT. No.C1970030
  • CAS. No.651054-52-3
  • Mol. F.C19H18N2O4
  • Mol. W.338.36 g/mol
  • Stock Status:Custom Synthesis
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Cabozantinib Impurity 26
Cabozantinib Impurity 26
  • CAT. No.C1970031
  • CAS. No.NA
  • Mol. F.C56H48F2N6O10
  • Mol. W.1003.01 g/mol
  • Stock Status:Custom Synthesis
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Cabozantinib Impurity 5
Cabozantinib Impurity 5
  • CAT. No.C1970032
  • CAS. No.1431468-36-8
  • Mol. F.C17H14F2N2O2
  • Mol. W.316.30 g/mol
  • Stock Status:Custom Synthesis
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Cabozantinib Impurity 12
Cabozantinib Impurity 12
  • CAT. No.C1970033
  • CAS. No.748707-58-6
  • Mol. F.C17H16N2O3
  • Mol. W.296.32 g/mol
  • Stock Status:Custom Synthesis
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Cabozantinib Impurity 27
Cabozantinib Impurity 27
  • CAT. No.C1970034
  • CAS. No.NA
  • Mol. F.C23H22N2O5
  • Mol. W.406.43 g/mol
  • Stock Status:Custom Synthesis
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Cabozantinib Desmethyl Impurity 1
Cabozantinib Desmethyl Impurity 1
  • CAT. No.C1970035
  • CAS. No.1628530-42-6
  • Mol. F.C27H22FN3O5
  • Mol. W.487.48 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Cabozantinib Impurity 1
N-Nitroso Cabozantinib Impurity 1
  • CAT. No.C1970036
  • CAS. No.NA
  • Mol. F.C12H13N3O6
  • Mol. W.295.25 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Cabozantinib
N-Nitroso Cabozantinib
  • CAT. No.C1970037
  • CAS. No.NA
  • Mol. F.C28H23FN4O6
  • Mol. W.530.50 g/mol
  • Stock Status:Custom Synthesis
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Cabozantinib Nitroso Impurity 2
Cabozantinib Nitroso Impurity 2
  • CAT. No.C1970038
  • CAS. No.NA
  • Mol. F.C17H15N3O4
  • Mol. W.325.32 g/mol
  • Stock Status:Custom Synthesis
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Cabozantinib Nitroso Impurity 3
Cabozantinib Nitroso Impurity 3
  • CAT. No.C1970039
  • CAS. No.NA
  • Mol. F.C15H16N2O7
  • Mol. W.336.30 g/mol
  • Stock Status:Custom Synthesis
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Cabozantinib 6 Hydroxy Impurity
Cabozantinib 6 Hydroxy Impurity
  • CAT. No.C1970040
  • CAS. No.1628530-47-1
  • Mol. F.C27H22FN3O5
  • Mol. W.487.48 g/mol
  • Stock Status:Custom Synthesis
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Cabozantinib Impurity 38
Cabozantinib Impurity 38
  • CAT. No.C1970041
  • CAS. No.NA
  • Mol. F.C28H23F2N3O5
  • Mol. W.519.50 g/mol
  • Stock Status:Custom Synthesis
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Open ring hydroxy Cabozantinib
Open ring hydroxy Cabozantinib
  • CAT. No.C1970042
  • CAS. No.NA
  • Mol. F.C28H26FN3O6
  • Mol. W.519.52 g/mol
  • Stock Status:Custom Synthesis
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Cabozantinib Impurity 4
Cabozantinib Impurity 4
  • CAT. No.C1970043
  • CAS. No.190728-27-9
  • Mol. F.C17H16N2O3
  • Mol. W.296.30 g/mol
  • Stock Status:Custom Synthesis
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Cabozantinib Impurity 8
Cabozantinib Impurity 8
  • CAT. No.C1970044
  • CAS. No.202917-04-2
  • Mol. F.C17H16N2O3
  • Mol. W.296.30 g/mol
  • Stock Status:Custom Synthesis
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Cabozantinib Impurity 3
Cabozantinib Impurity 3
  • CAT. No.C1970045
  • CAS. No.1628530-38-0
  • Mol. F.C28H24FN3O6
  • Mol. W.517.51 g/mol
  • Stock Status:Custom Synthesis
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Cabozantinib Impurity 10
Cabozantinib Impurity 10
  • CAT. No.C1970046
  • CAS. No.2146-07-8
  • Mol. F.C6H6FN.HCl
  • Mol. W.147.58 g/mol
  • Stock Status:Custom Synthesis
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Isotope Labelled Compounds

Cabozantinib D4
Cabozantinib D4
  • CAT. No.C1970001
  • CAS. No.NA
  • Mol. F.C28H20D4FN3O5
  • Mol. W.505.54 g/mol
  • Stock Status:Instock
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Cabozantinib D6
Cabozantinib D6
  • CAT. No.C1970010
  • CAS. No.1802168-46-2
  • Mol. F.C28H18D6FN3O5
  • Mol. W.507.54 g/mol
  • Stock Status:Limited Stock
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