Diclofenac Sodium Related Compounds & Impurities

Diclofenac Sodium is a sodium-salt phenylacetic-acid NSAID with preferential COX-2 inhibition, one of the most widely prescribed anti-inflammatory and analgesic drugs globally.

Simson Pharma Limited along with its subsidiary offices Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) is a trusted manufacturer and supplier of high-quality pharmaceutical reference standards, offering a comprehensive portfolio of Diclofenac Sodium reference standards, pharmacopeial and non-pharmacopeial Diclofenac Sodium impurities, related compounds, related substances, metabolites, stable isotope-labelled compounds, deuterium labelled compounds and nitrosamine (N-NO) reference standards.

These materials support pharmaceutical research and development, product development, ANDA and DMF submissions, quality control (QC), analytical method development and validation, stability studies, impurity identification, and genotoxic impurity assessment.

Our Diclofenac Sodium-related reference standards are thoroughly characterized using advanced analytical techniques and are supplied with comprehensive Certificates of Analysis (COA) and supporting analytical data from our USFDA certified, ISO 17025 and ISO 17034 accredited Lab, to meet global regulatory expectations. EP and USP traceable reference standards can also be provided upon request, subject to availability. Simson is also a provider of EP and USP traceable standards. To ensure consistent quality and reliability, our reference standards are periodically re-tested according to established quality management procedures.

Pharmaceutical Reference Standards / Impurity Standards

Diclofenac Sodium
Diclofenac Sodium
  • CAT. No.D010000
  • CAS. No.15307-79-6
  • Mol. F.C14H10Cl2NO2.Na
  • Mol. W.318.13 g/mol
  • Stock Status:Instock
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Diclofenac Epolamine
Diclofenac Epolamine
  • CAT. No.D010000B
  • CAS. No.119623-66-4
  • Mol. F.C14H11Cl2NO2.C6H13NO
  • Mol. W.411.32 g/mol
  • Stock Status:Custom Synthesis
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Diclofenac EP Impurity A
Diclofenac EP Impurity A
  • CAT. No.D010001
  • CAS. No.15362-40-0
  • Mol. F.C14H9Cl2NO
  • Mol. W.278.13 g/mol
  • Stock Status:Instock
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Diclofenac Impurity B
Diclofenac Impurity B
  • CAT. No.D010002
  • CAS. No.22121-58-0
  • Mol. F.C13H9Cl2NO
  • Mol. W.266.12 g/mol
  • Stock Status:Instock
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Diclofenac EP Impurity C
Diclofenac EP Impurity C
  • CAT. No.D010003
  • CAS. No.27204-57-5
  • Mol. F.C13H11Cl2NO
  • Mol. W.268.14 g/mol
  • Stock Status:Instock
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Diclofenac EP Impurity D
Diclofenac EP Impurity D
  • CAT. No.D010004
  • CAS. No.127792-23-8
  • Mol. F.C14H11BrClNO2
  • Mol. W.340.60 g/mol
  • Stock Status:Instock
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Diclofenac EP Impurity D (Sodium Salt)
Diclofenac EP Impurity D (Sodium Salt)
  • CAT. No.D010004A
  • CAS. No.127792-45-4
  • Mol. F.C14H10BrClNNaO2
  • Mol. W.362.58 g/mol
  • Stock Status:Instock
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Diclofenac EP Impurity E
Diclofenac EP Impurity E
  • CAT. No.D010005
  • CAS. No.59-48-3
  • Mol. F.C8H7NO
  • Mol. W.133.15 g/mol
  • Stock Status:Instock
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Diclofenac Carboxylic Acid
Diclofenac Carboxylic Acid
  • CAT. No.D010007
  • CAS. No.13625-57-5
  • Mol. F.C13H9Cl2NO2
  • Mol. W.282.12 g/mol
  • Stock Status:Instock
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Diclofenac Potassium
Diclofenac Potassium
  • CAT. No.D010010
  • CAS. No.15307-81-0
  • Mol. F.C14H10Cl2NO2.K
  • Mol. W.334.24 g/mol
  • Stock Status:Instock
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Diclofenac Potassium Standard
Diclofenac Potassium Standard
  • CAT. No.D010010A
  • CAS. No.15307-81-0
  • Mol. F.C14H10Cl2KNO2
  • Mol. W.334.24 g/mol
  • Stock Status:Limited Stock
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Diclofenac Diethyl Amine Salt
Diclofenac Diethyl Amine Salt
  • CAT. No.D010011
  • CAS. No.78213-16-8
  • Mol. F.C18H22Cl2N2O2
  • Mol. W.369.29 g/mol
  • Stock Status:Instock
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2-Bromo-6-chlorobenzoic acid
2-Bromo-6-chlorobenzoic acid
  • CAT. No.D010012
  • CAS. No.93224-85-2
  • Mol. F.C7H4BrClO2
  • Mol. W.235.47 g/mol
  • Stock Status:Instock
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Diclofenac EP Impurity F
Diclofenac EP Impurity F
  • CAT. No.D010013
  • CAS. No.560075-65-2
  • Mol. F.C14H10Cl3NO
  • Mol. W.314.59 g/mol
  • Stock Status:Limited Stock
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Diclofenac Impurity 27
Diclofenac Impurity 27
  • CAT. No.D010015
  • CAS. No.1609187-30-5
  • Mol. F.C28H20Cl4N2O4
  • Mol. W.590.28 g/mol
  • Stock Status:Instock
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Diclofenac Impurity 17
Diclofenac Impurity 17
  • CAT. No.D010016
  • CAS. No.24542-74-3
  • Mol. F.C14H7Cl2NO2
  • Mol. W.292.12 g/mol
  • Stock Status:Instock
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Diclofenac Desacetate Impurity
Diclofenac Desacetate Impurity
  • CAT. No.D010018
  • CAS. No.15307-93-4
  • Mol. F.C12H9Cl2N
  • Mol. W.238.11 g/mol
  • Stock Status:Instock
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Diclofenac Isopropyl Ester
Diclofenac Isopropyl Ester
  • CAT. No.D010019
  • CAS. No.66370-79-4
  • Mol. F.C17H17Cl2NO2
  • Mol. W.338.23 g/mol
  • Stock Status:Instock
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Diclofenac bromo impurity
Diclofenac bromo impurity
  • CAT. No.D010022
  • CAS. No.1219112-85-2
  • Mol. F.C14H9BrClNO
  • Mol. W.322.58 g/mol
  • Stock Status:Custom Synthesis
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Keto Diclofenac Sodium Salt
Keto Diclofenac Sodium Salt
  • CAT. No.D010023
  • CAS. No.70757-34-5
  • Mol. F.C14H8Cl2NNaO3
  • Mol. W.332.11 g/mol
  • Stock Status:Instock
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Diclofenac Keto Analog
Diclofenac Keto Analog
  • CAT. No.D010023A
  • CAS. No.66156-75-0
  • Mol. F.C14H9Cl2NO3
  • Mol. W.310.13 g/mol
  • Stock Status:Custom Synthesis
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Diclofenac Chloroacetyl Impurity
Diclofenac Chloroacetyl Impurity
  • CAT. No.D010024
  • CAS. No.15308-01-7
  • Mol. F.C14H10Cl3NO
  • Mol. W.314.59 g/mol
  • Stock Status:Instock
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Diclofenac Dodecyl Ester
Diclofenac Dodecyl Ester
  • CAT. No.D010025
  • CAS. No.NA
  • Mol. F.C26H35Cl2NO2
  • Mol. W.464.47 g/mol
  • Stock Status:Custom Synthesis
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Diclofenac PEG ester
Diclofenac PEG ester
  • CAT. No.D010027
  • CAS. No.120339-19-7
  • Mol. F.C16H15Cl2NO3
  • Mol. W.340.20 g/mol
  • Stock Status:Custom Synthesis
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2-Chloro-N-phenylacetamide
2-Chloro-N-phenylacetamide
  • CAT. No.D010028
  • CAS. No.587-65-5
  • Mol. F.C8H8ClNO
  • Mol. W.169.61 g/mol
  • Stock Status:Instock
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Diclofenac Glyceryl Adduct
Diclofenac Glyceryl Adduct
  • CAT. No.D010030
  • CAS. No.221016-39-3
  • Mol. F.C17H17Cl2NO4
  • Mol. W.370.23 g/mol
  • Stock Status:Custom Synthesis
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Diclofenac Related Compound 14
Diclofenac Related Compound 14
  • CAT. No.D010033
  • CAS. No.3644-56-2
  • Mol. F.C8H6Cl3NO
  • Mol. W.238.5 g/mol
  • Stock Status:Instock
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Diclofenac Impurity 3
Diclofenac Impurity 3
  • CAT. No.D010034
  • CAS. No.131023-44-4
  • Mol. F.C14H10ClNO2
  • Mol. W.259.69 g/mol
  • Stock Status:Instock
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Diclofenac Impurity 4
Diclofenac Impurity 4
  • CAT. No.D010035
  • CAS. No.131023-43-3
  • Mol. F.C14H11NO2
  • Mol. W.225.24 g/mol
  • Stock Status:Instock
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Diclofenac Acyl-beta-D-glucuronide
Diclofenac Acyl-beta-D-glucuronide
  • CAT. No.D010036
  • CAS. No.64118-81-6
  • Mol. F.C20H19Cl2NO8
  • Mol. W.472.27 g/mol
  • Stock Status:Limited Stock
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1-(2,6-dichlorophenyl)-1-2-dihydrobenzo[b]azete
1-(2,6-dichlorophenyl)-1-2-dihydrobenzo[b]azete
  • CAT. No.D010037
  • CAS. No.NA
  • Mol. F.C13H9Cl2N
  • Mol. W.250.12 g/mol
  • Stock Status:Custom Synthesis
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Diclofenac Related Compound 1
Diclofenac Related Compound 1
  • CAT. No.D010039
  • CAS. No.928343-25-3
  • Mol. F.C14H9Cl2NO3
  • Mol. W.310.13 g/mol
  • Stock Status:Custom Synthesis
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Diclofenac 2,5-Quinone Imine
Diclofenac 2,5-Quinone Imine
  • CAT. No.D010040
  • CAS. No.1254576-93-6
  • Mol. F.C14H9Cl2NO3
  • Mol. W.310.13 g/mol
  • Stock Status:Limited Stock
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Diclofenac Impurity 13
Diclofenac Impurity 13
  • CAT. No.D010041
  • CAS. No.1205-40-9
  • Mol. F.C12H10ClN
  • Mol. W.203.67 g/mol
  • Stock Status:Custom Synthesis
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Diclofenac Impurity 14
Diclofenac Impurity 14
  • CAT. No.D010042
  • CAS. No.58373-59-4
  • Mol. F.C12H9Cl2N
  • Mol. W.238.11 g/mol
  • Stock Status:Custom Synthesis
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Diclofenac Dimer Impurity
Diclofenac Dimer Impurity
  • CAT. No.D010043
  • CAS. No.1609187-32-7
  • Mol. F.C28H20Cl4N2O4
  • Mol. W.590.28 g/mol
  • Stock Status:Instock
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N-dichloroacetyl-2,6-dichlorodiphenylamine
N-dichloroacetyl-2,6-dichlorodiphenylamine
  • CAT. No.D010044
  • CAS. No.NA
  • Mol. F.C14H9Cl4NO
  • Mol. W.349.04 g/mol
  • Stock Status:Instock
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N-Nitrosodiclofenac
N-Nitrosodiclofenac
  • CAT. No.D010045
  • CAS. No.66505-80-4
  • Mol. F.C14H10Cl2N2O3
  • Mol. W.325.15 g/mol
  • Stock Status:Instock
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3-amino-1-(2,6-dichlorophenyl)-3H-indol-2-one
3-amino-1-(2,6-dichlorophenyl)-3H-indol-2-one
  • CAT. No.D010046
  • CAS. No.NA
  • Mol. F.C14H10Cl2N2O
  • Mol. W.293.15 g/mol
  • Stock Status:Custom Synthesis
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Diclofenac Impurity 8
Diclofenac Impurity 8
  • CAT. No.D010047
  • CAS. No.95093-56-4
  • Mol. F.C17H17Cl2NO3
  • Mol. W.354.23 g/mol
  • Stock Status:Custom Synthesis
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(E)-1-(2,6-Dichlorophenyl)-3-ethylideneindolin-2-one
(E)-1-(2,6-Dichlorophenyl)-3-ethylideneindolin-2-one
  • CAT. No.D010049
  • CAS. No.NA
  • Mol. F.C16H11Cl2NO
  • Mol. W.304.17 g/mol
  • Stock Status:Custom Synthesis
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(Z)-1-(2,6-Dichlorophenyl)-3-ethylideneindolin-2-one
(Z)-1-(2,6-Dichlorophenyl)-3-ethylideneindolin-2-one
  • CAT. No.D010050
  • CAS. No.NA
  • Mol. F.C16H11Cl2NO
  • Mol. W.304.17 g/mol
  • Stock Status:Custom Synthesis
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Diclofenac Diethanolamine
Diclofenac Diethanolamine
  • CAT. No.D010051
  • CAS. No.80636-44-8
  • Mol. F.C18H22Cl2N2O4
  • Mol. W.401.28 g/mol
  • Stock Status:Custom Synthesis
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Diclofenac Impurity 31
Diclofenac Impurity 31
  • CAT. No.D010053
  • CAS. No.575-90-6
  • Mol. F.C8H6Cl2O3
  • Mol. W.221.04 g/mol
  • Stock Status:Custom Synthesis
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2-methoxy-2-oxoethyl2-(2-((2,6-dichlorophenyl)(nitroso)amino)phenyl)acetate
2-methoxy-2-oxoethyl2-(2-((2,6-dichlorophenyl)(nitroso)amino)phenyl)acetate
  • CAT. No.D010054
  • CAS. No.NA
  • Mol. F.C17H14Cl2N2O5
  • Mol. W.397.21 g/mol
  • Stock Status:Custom Synthesis
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Diclofenac Desacetate Nitroso Impurity
Diclofenac Desacetate Nitroso Impurity
  • CAT. No.D010056
  • CAS. No.NA
  • Mol. F.C12H8Cl2N2O
  • Mol. W.267.10 g/mol
  • Stock Status:Custom Synthesis
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Diclofenac Impurity 33
Diclofenac Impurity 33
  • CAT. No.D010057
  • CAS. No.NA
  • Mol. F.C14H22N2O3
  • Mol. W.266.34 g/mol
  • Stock Status:Custom Synthesis
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Diclofenac Nitroso Impurity 1
Diclofenac Nitroso Impurity 1
  • CAT. No.D010058
  • CAS. No.68962-15-2
  • Mol. F.C12H9ClN2O
  • Mol. W.232.67 g/mol
  • Stock Status:Custom Synthesis
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3`-Hydroxydiclofenac
3`-Hydroxydiclofenac
  • CAT. No.D010059
  • CAS. No.69002-85-3
  • Mol. F.C14H11Cl2NO3
  • Mol. W.312.15 g/mol
  • Stock Status:Custom Synthesis
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o-Chloroacetanilide
o-Chloroacetanilide
  • CAT. No.D010060
  • CAS. No.533-17-5
  • Mol. F.C8H8ClNO
  • Mol. W.169.61 g/mol
  • Stock Status:Custom Synthesis
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Diclofenac (E/Z Mixture) Impurity 18
Diclofenac (E/Z Mixture) Impurity 18
  • CAT. No.D010062
  • CAS. No.NA
  • Mol. F.C16H11Cl2NO
  • Mol. W.304.17 g/mol
  • Stock Status:Custom Synthesis
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Diclofenac Cholestyramine
Diclofenac Cholestyramine
  • CAT. No.D010063
  • CAS. No.NA
  • Mol. F.NA
  • Mol. W.NA
  • Stock Status:Custom Synthesis
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N-Hydroxy Diclofenac
N-Hydroxy Diclofenac
  • CAT. No.D010064
  • CAS. No.NA
  • Mol. F.C14H11Cl2NO3
  • Mol. W.312.15 g/mol
  • Stock Status:Custom Synthesis
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Diclofenac Impurity 34
Diclofenac Impurity 34
  • CAT. No.D010065
  • CAS. No.3342-78-7
  • Mol. F.C8H9NO2
  • Mol. W.151.17 g/mol
  • Stock Status:Custom Synthesis
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Diclofenac Impurity 29
Diclofenac Impurity 29
  • CAT. No.D010066
  • CAS. No.101-87-1
  • Mol. F.C18H22N2
  • Mol. W.266.38 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Diclofenac EP Impurity B
N-Nitroso Diclofenac EP Impurity B
  • CAT. No.D010067
  • CAS. No.NA
  • Mol. F.C13H8Cl2N2O2
  • Mol. W.295.10 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Diclofenac EP Impurity C
N-Nitroso Diclofenac EP Impurity C
  • CAT. No.D010068
  • CAS. No.NA
  • Mol. F.C13H10Cl2N2O2
  • Mol. W.297.10 g/mol
  • Stock Status:Custom Synthesis
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Diclofenac-propyleneglycolester (Mixture of primary and secondary)Primary Ester
Diclofenac-propyleneglycolester (Mixture of primary and secondary)Primary Ester
  • CAT. No.D010069
  • CAS. No.NA
  • Mol. F.C17H17Cl2NO3
  • Mol. W.354.22 g/mol
  • Stock Status:Custom Synthesis
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4-Hydroxy Diclofenac Acyl Glucuronide
4-Hydroxy Diclofenac Acyl Glucuronide
  • CAT. No.D010070
  • CAS. No.NA
  • Mol. F.C20H19Cl2NO9
  • Mol. W.488.27 g/mol
  • Stock Status:Custom Synthesis
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Diclofenac bromo impurity 1
Diclofenac bromo impurity 1
  • CAT. No.D010071
  • CAS. No.NA
  • Mol. F.C14H11BrClNO2
  • Mol. W.340.60 g/mol
  • Stock Status:Instock
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Diclofenac Impurity 1
Diclofenac Impurity 1
  • CAT. No.D010072
  • CAS. No.614-75-5
  • Mol. F.C8H8O3
  • Mol. W.152.15 g/mol
  • Stock Status:Custom Synthesis
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Diclofenac Impurity 5
Diclofenac Impurity 5
  • CAT. No.D010073
  • CAS. No.146607-19-4
  • Mol. F.C14H11Cl2NO2
  • Mol. W.296.15 g/mol
  • Stock Status:Custom Synthesis
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Diclofenac Levomenthol ester
Diclofenac Levomenthol ester
  • CAT. No.D010074
  • CAS. No.2648862-09-1
  • Mol. F.C24H29Cl2NO2
  • Mol. W.434.40 g/mol
  • Stock Status:Custom Synthesis
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Diclofenac Impurity 6
Diclofenac Impurity 6
  • CAT. No.D010075
  • CAS. No.2180935-53-7
  • Mol. F.C28H20Cl4N2O4
  • Mol. W.590.30 g/mol
  • Stock Status:Custom Synthesis
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Isotope Labelled Compounds

Diclofenac D4
Diclofenac D4
  • CAT. No.D010020
  • CAS. No.153466-65-0
  • Mol. F.C14H7Cl2D4NO2
  • Mol. W.300.17 g/mol
  • Stock Status:Instock
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Diclofenac 13C6-Sodium Salt
Diclofenac 13C6-Sodium Salt
  • CAT. No.D010021
  • CAS. No.1261393-73-0
  • Mol. F.C813C6H10Cl2NNaO2
  • Mol. W.324.07 g/mol
  • Stock Status:Instock
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Diclofenac - D6
Diclofenac - D6
  • CAT. No.D010026
  • CAS. No.NA
  • Mol. F.C14H5D6Cl2NO2
  • Mol. W.302.19 g/mol
  • Stock Status:Custom Synthesis
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Diclofenac 13C6-Na Hydrate
Diclofenac 13C6-Na Hydrate
  • CAT. No.D010029
  • CAS. No.NA
  • Mol. F.C813C6H10Cl2NNaO2.4.5H2O
  • Mol. W.405.07 g/mol [324.09g/mol (anhydrous); 302.10g/mol (acid)]
  • Stock Status:Under Synthesis
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4`-Hydroxy Diclofenac-D4
4`-Hydroxy Diclofenac-D4
  • CAT. No.D010052
  • CAS. No.254762-27-1
  • Mol. F.C14H7D4Cl2NO3
  • Mol. W.316.17 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Diclofenac D4
N-Nitroso Diclofenac D4
  • CAT. No.D010055
  • CAS. No.NA
  • Mol. F.C14H6D4Cl2N2O3
  • Mol. W.329.20 g/mol
  • Stock Status:Custom Synthesis
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