Deferasirox Related Compounds & Impurities

Deferasirox is a selective, orally active tridentate iron chelator that binds ferric iron with high affinity and promotes its renal excretion, approved for chronic transfusional iron overload and non-transfusion-dependent thalassaemia.

Simson Pharma Limited along with its subsidiary offices Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) is a trusted manufacturer and supplier of high-quality pharmaceutical reference standards, offering a comprehensive portfolio of Deferasirox reference standards, pharmacopeial and non-pharmacopeial Deferasirox impurities, related compounds, related substances, metabolites, stable isotope-labelled compounds, deuterium labelled compounds and nitrosamine (N-NO) reference standards.

These materials support pharmaceutical research and development, product development, ANDA and DMF submissions, quality control (QC), analytical method development and validation, stability studies, impurity identification, and genotoxic impurity assessment.

Our Deferasirox-related reference standards are thoroughly characterized using advanced analytical techniques and are supplied with comprehensive Certificates of Analysis (COA) and supporting analytical data from our USFDA certified, ISO 17025 and ISO 17034 accredited Lab, to meet global regulatory expectations. EP and USP traceable reference standards can also be provided upon request, subject to availability. Simson is also a provider of EP and USP traceable standards. To ensure consistent quality and reliability, our reference standards are periodically re-tested according to established quality management procedures.

Pharmaceutical Reference Standards / Impurity Standards

Deferasirox
Deferasirox
  • CAT. No.D420000
  • CAS. No.201530-41-8
  • Mol. F.C21H15N3O4
  • Mol. W.373.36 g/mol
  • Stock Status:Instock
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Deferasirox EP Impurity F
Deferasirox EP Impurity F
  • CAT. No.D420001
  • CAS. No.619-67-0
  • Mol. F.C7H8N2O2
  • Mol. W.152.15 g/mol
  • Stock Status:Instock
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Deferasirox EP Impurity B
Deferasirox EP Impurity B
  • CAT. No.D420002
  • CAS. No.1218-69-5
  • Mol. F.C14H9NO3
  • Mol. W.239.22 g/mol
  • Stock Status:Instock
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Deferasirox EP Impurity E
Deferasirox EP Impurity E
  • CAT. No.D420003
  • CAS. No.201530-79-2
  • Mol. F.C23H19N3O4
  • Mol. W.401.41 g/mol
  • Stock Status:Instock
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2-(2-salicyloylphenyl)-4H-1,3-benzoxazin-4-one
2-(2-salicyloylphenyl)-4H-1,3-benzoxazin-4-one
  • CAT. No.D420004
  • CAS. No.NA
  • Mol. F.C21H13NO4
  • Mol. W.343.33 g/mol
  • Stock Status:Instock
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Deferasirox Methyl Ester
Deferasirox Methyl Ester
  • CAT. No.D420006
  • CAS. No.1266741-05-2
  • Mol. F.C22H17N3O4
  • Mol. W.387.39 g/mol
  • Stock Status:Instock
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Deferasirox Disalicylimide impurity
Deferasirox Disalicylimide impurity
  • CAT. No.D420007
  • CAS. No.1972-71-0
  • Mol. F.C14H11NO4
  • Mol. W.257.20 g/mol
  • Stock Status:Instock
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Deferasirox Isopropyl Ester
Deferasirox Isopropyl Ester
  • CAT. No.D420008
  • CAS. No.1266741-29-0
  • Mol. F.C24H21N3O4
  • Mol. W.415.40 g/mol
  • Stock Status:Instock
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Deferasirox Impurity 7
Deferasirox Impurity 7
  • CAT. No.D420009
  • CAS. No.858425-08-8
  • Mol. F.C16H15NO4
  • Mol. W.285.29 g/mol
  • Stock Status:Custom Synthesis
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2-ethoxy-N-(2-hydroxybenzoyl)benzamide
2-ethoxy-N-(2-hydroxybenzoyl)benzamide
  • CAT. No.D420010
  • CAS. No.NA
  • Mol. F.C16H15NO4
  • Mol. W.285.29 g/mol
  • Stock Status:Custom Synthesis
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Deferasirox Impurity 5
Deferasirox Impurity 5
  • CAT. No.D420011
  • CAS. No.524746-11-0
  • Mol. F.C21H15N3O5
  • Mol. W.389.37 g/mol
  • Stock Status:Custom Synthesis
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Deferasirox Sulfoxide Dimer
Deferasirox Sulfoxide Dimer
  • CAT. No.D420012
  • CAS. No.1688656-84-9
  • Mol. F.C42H28N6O9S
  • Mol. W.792.77 g/mol
  • Stock Status:Instock
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Deferasirox Ferrate (III) Tripotassium Complex
Deferasirox Ferrate (III) Tripotassium Complex
  • CAT. No.D420013
  • CAS. No.554445-58-8
  • Mol. F.C42H24FeK3N6O8
  • Mol. W.913.82 g/mol
  • Stock Status:Limited Stock
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Deferasirox EP Impurity C
Deferasirox EP Impurity C
  • CAT. No.D420014
  • CAS. No.201530-78-1
  • Mol. F.C21H15N3O4
  • Mol. W.373.36 g/mol
  • Stock Status:Instock
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Deferasirox 1,3-isomer
Deferasirox 1,3-isomer
  • CAT. No.D420015
  • CAS. No.2254105-61-6
  • Mol. F.C21H15N3O4
  • Mol. W.373.36 g/mol
  • Stock Status:Instock
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Deferasirox Impurity 24
Deferasirox Impurity 24
  • CAT. No.D420016
  • CAS. No.86245-87-6
  • Mol. F.C20H15N3O2
  • Mol. W.329.35 g/mol
  • Stock Status:Instock
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Deferasirox Salicyloyl Ester
Deferasirox Salicyloyl Ester
  • CAT. No.D420019
  • CAS. No.1395346-28-7
  • Mol. F.C28H19N3O6
  • Mol. W.493.47 g/mol
  • Stock Status:Custom Synthesis
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Deferasirox EP Impurity D
Deferasirox EP Impurity D
  • CAT. No.D420022
  • CAS. No.2254105-61-6
  • Mol. F.C21H15N3O4
  • Mol. W.373.36 g/mol
  • Stock Status:Custom Synthesis
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Deferasirox Azide Impurity
Deferasirox Azide Impurity
  • CAT. No.D420023
  • CAS. No.6427-66-3
  • Mol. F.C7H5N3O2
  • Mol. W.163.13 g/mol
  • Stock Status:Instock
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Deferasirox Amide Impurity
Deferasirox Amide Impurity
  • CAT. No.D420024
  • CAS. No.NA
  • Mol. F.C14H12N2O4
  • Mol. W.272.26 g/mol
  • Stock Status:Custom Synthesis
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Deferasirox Impurity 14
Deferasirox Impurity 14
  • CAT. No.D420025
  • CAS. No.1688656-83-8
  • Mol. F.C42H28N6O8S
  • Mol. W.776.78 g/mol
  • Stock Status:Custom Synthesis
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Deferasirox Impurity 12
Deferasirox Impurity 12
  • CAT. No.D420026
  • CAS. No.1688656-86-1
  • Mol. F.C28H16N2O6S
  • Mol. W.508.50 g/mol
  • Stock Status:Instock
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2-Hydrazinobenzoic Acid
2-Hydrazinobenzoic Acid
  • CAT. No.D420027
  • CAS. No.5326-27-2
  • Mol. F.C7H8N2O2
  • Mol. W.152.15 g/mol
  • Stock Status:Custom Synthesis
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2-Hydrazinobenzoic Acid Hydrochloride
2-Hydrazinobenzoic Acid Hydrochloride
  • CAT. No.D420027A
  • CAS. No.NA
  • Mol. F.C7H8N2O2.HCl
  • Mol. W.188.61 g/mol
  • Stock Status:Custom Synthesis
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3-Hydrazinobenzoic Acid
3-Hydrazinobenzoic Acid
  • CAT. No.D420028
  • CAS. No.38235-71-1
  • Mol. F.C7H8N2O2
  • Mol. W.152.15 g/mol
  • Stock Status:Instock
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(2-hydroxy-N-(2-hydroxyphenyl)carbonyl benzamide)
(2-hydroxy-N-(2-hydroxyphenyl)carbonyl benzamide)
  • CAT. No.D420029
  • CAS. No.NA
  • Mol. F.C14H11NO4
  • Mol. W.257.24 g/mol
  • Stock Status:Custom Synthesis
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Deferasirox Impurity 17
Deferasirox Impurity 17
  • CAT. No.D420034
  • CAS. No.1914179-49-9
  • Mol. F.C14H11N3O4
  • Mol. W.285.25 g/mol
  • Stock Status:Custom Synthesis
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4-[5-(2-chlorophenyl)-3-(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic acid
4-[5-(2-chlorophenyl)-3-(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic acid
  • CAT. No.D420035
  • CAS. No.NA
  • Mol. F.C21H14ClN3O3
  • Mol. W.391.81 g/mol
  • Stock Status:Custom Synthesis
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Mefenamic Acid Nitroso Impurity 1
Mefenamic Acid Nitroso Impurity 1
  • CAT. No.D420036
  • CAS. No.91673-51-7
  • Mol. F.C7H6N2O3
  • Mol. W.166.13 g/mol
  • Stock Status:Custom Synthesis
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Deferasirox Impurity 1
Deferasirox Impurity 1
  • CAT. No.D420037
  • CAS. No.6296-89-5
  • Mol. F.C8H10N2O2.HCl
  • Mol. W.202.64 g/mol
  • Stock Status:Instock
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4-(3-(5-((3-(1-(4-carboxyphenyl)-3-(2-hydroxyphenyl)-1H-1,2,4-triazol-5-yl)-4-hydroxyphenyl)thio)-2-hydroxyphenyl)-5-(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl)benzoic acid
4-(3-(5-((3-(1-(4-carboxyphenyl)-3-(2-hydroxyphenyl)-1H-1,2,4-triazol-5-yl)-4-hydroxyphenyl)thio)-2-hydroxyphenyl)-5-(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl)benzoic acid
  • CAT. No.D420038
  • CAS. No.NA
  • Mol. F.C42H28N6O8S
  • Mol. W.776.77 g/mol
  • Stock Status:Instock
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2,2`-(sulfonylbis(2-hydroxy-5,1-phenylene))bis(4H-benzo[e][1,3]oxazin-4-one)
2,2`-(sulfonylbis(2-hydroxy-5,1-phenylene))bis(4H-benzo[e][1,3]oxazin-4-one)
  • CAT. No.D420039
  • CAS. No.NA
  • Mol. F.C28H16N2O8S
  • Mol. W.540.50 g/mol
  • Stock Status:Custom Synthesis
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Deferasirox Impurity 20
Deferasirox Impurity 20
  • CAT. No.D420043
  • CAS. No.586-91-4
  • Mol. F.C14H10N2O4
  • Mol. W.270.24 g/mol
  • Stock Status:Custom Synthesis
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Deferasirox Impurity 23
Deferasirox Impurity 23
  • CAT. No.D420044
  • CAS. No.2732310-58-4
  • Mol. F.C21H13NO5
  • Mol. W.359.30 g/mol
  • Stock Status:Custom Synthesis
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Deferasirox O-salycyl Impurity
Deferasirox O-salycyl Impurity
  • CAT. No.D420045
  • CAS. No.6543-57-3
  • Mol. F.C28H16O8
  • Mol. W.480.42 g/mol
  • Stock Status:Custom Synthesis
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Deferasirox Impurity 26
Deferasirox Impurity 26
  • CAT. No.D420046
  • CAS. No.NA
  • Mol. F.C10H12N2O2
  • Mol. W.192.21 g/mol
  • Stock Status:Custom Synthesis
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Deferasirox Impurity 3
Deferasirox Impurity 3
  • CAT. No.D420047
  • CAS. No.NA
  • Mol. F.C21H15NO5
  • Mol. W.361.35 g/mol
  • Stock Status:Custom Synthesis
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Deferasirox Impurity 4
Deferasirox Impurity 4
  • CAT. No.D420048
  • CAS. No.108129-45-9
  • Mol. F.C8H8N2O3
  • Mol. W.180.16 g/mol
  • Stock Status:Custom Synthesis
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Metabolites

5-Hydroxy Deferasirox(Metabolite M1)
5-Hydroxy Deferasirox(Metabolite M1)
  • CAT. No.D420040
  • CAS. No.524746-12-1
  • Mol. F.C21H15N3O5
  • Mol. W.389.36 g/mol
  • Stock Status:Custom Synthesis
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5`-Hydroxy Deferasirox (Metabolite M4)
5`-Hydroxy Deferasirox (Metabolite M4)
  • CAT. No.D420041
  • CAS. No.524746-13-2
  • Mol. F.C21H15N3O5
  • Mol. W.389.36 g/mol
  • Stock Status:Custom Synthesis
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Deferasirox Acyl-Beta-D-Glucuronide
Deferasirox Acyl-Beta-D-Glucuronide
  • CAT. No.D420042
  • CAS. No.1233196-91-2
  • Mol. F.C27H23N3O10
  • Mol. W.549.49 g/mol
  • Stock Status:Custom Synthesis
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Isotope Labelled Compounds

Deferasirox-D4
Deferasirox-D4
  • CAT. No.D420005
  • CAS. No.1133425-75-8
  • Mol. F.C21H11N3O4D4
  • Mol. W.377.39 g/mol
  • Stock Status:Limited Stock
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Deferasirox-D8
Deferasirox-D8
  • CAT. No.D420017
  • CAS. No.NA
  • Mol. F.C21H7D8N3O4
  • Mol. W.381.41 g/mol
  • Stock Status:Limited Stock
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[13C6]-Deferasirox
[13C6]-Deferasirox
  • CAT. No.D420031
  • CAS. No.1261392-79-3
  • Mol. F.C1513C6H15N3O4
  • Mol. W.379.32 g/mol
  • Stock Status:Custom Synthesis
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