Dextromethorphan Hydrobromide Related Compounds & Impurities

Dextromethorphan Hydrobromide is the most widely used OTC cough suppressant globally, acting via sigma-1.

Simson Pharma Limited along with its subsidiary offices Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) is a trusted manufacturer and supplier of high-quality pharmaceutical reference standards, offering a comprehensive portfolio of Dextromethorphan Hydrobromide reference standards, pharmacopeial and non-pharmacopeial Dextromethorphan Hydrobromide impurities, related compounds, related substances, metabolites, stable isotope-labelled compounds, deuterium labelled compounds and nitrosamine (N-NO) reference standards.

These materials support pharmaceutical research and development, product development, ANDA and DMF submissions, quality control (QC), analytical method development and validation, stability studies, impurity identification, and genotoxic impurity assessment.

Our Dextromethorphan Hydrobromide-related reference standards are thoroughly characterized using advanced analytical techniques and are supplied with comprehensive Certificates of Analysis (COA) and supporting analytical data from our USFDA certified, ISO 17025 and ISO 17034 accredited Lab, to meet global regulatory expectations. EP and USP traceable reference standards can also be provided upon request, subject to availability. Simson is also a provider of EP and USP traceable standards. To ensure consistent quality and reliability, our reference standards are periodically re-tested according to established quality management procedures.

Pharmaceutical Reference Standards / Impurity Standards

Dextromethorphan Hydrobromide
Dextromethorphan EP Impurity A Hydrochloride
3-Methoxymorphinan
Dextrorphan Tartrate
Dextromethorphan EP Impurity C
Dextromethorphan N-Oxide
(R)-N-Formyl Octabase
2-(1-Cyclohexenyl)ethylamine
Dextromethorphan EP Impurity D
N-Nitroso-1-(4-methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline
N-nitroso-3-methoxymorphinan
1-(4-methoxybenzyl)-3,4,5,6,7,8-hexahydroisoquinoline
N-Nitroso Dextromethorphan EP Impurity A
3-methoxy-N-methylmorphinan N-Oxide
3-methoxy-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene-11-carbaldehyde
(S)-1-(4-methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline
(R)-1,2,3,4,5,6,7,8-Octahydro-1-[(4-methoxyphenyl)methyl]isoquinoline
3-Methoxy-17-methyl-9alpha,13 alpha,14 beta-morphinan
Dextromethorphan Impurity 5
Dextromethorphan Impurity 11
Dextromethorphan N-Oxide
Dextromethorphan EP Impurity B Hydrochloride
Dextromethorphan Impurity 2
Dextromethorphan Impurity 1
Dextromethorphan Impurity 3
N-Nitroso-Octabase Impurity 1

Metabolites

Dextrorphan-beta-D-O-glucuronide

Isotope Labelled Compounds

Dextromethorphan D3
Dextromethorphan D3 Hydrobromide
Dextrorphan-D3
Dextrorphan D3 Tartrate
N-Desmethyl-N-Nitroso Dextromethorphan D3
Dextrorphan D3 beta-D-O-Glucuronide