Decitabine Related Compounds & Impurities

Decitabine is a deoxycytidine analogue that incorporates into DNA and traps DNA methyltransferases to cause hypomethylation, reactivating silenced tumour-suppressor genes in myelodysplastic syndromes and AML.

Simson Pharma Limited along with its subsidiary offices Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) is a trusted manufacturer and supplier of high-quality pharmaceutical reference standards, offering a comprehensive portfolio of Decitabine reference standards, pharmacopeial and non-pharmacopeial Decitabine impurities, related compounds, related substances, metabolites, stable isotope-labelled compounds, deuterium labelled compounds and nitrosamine (N-NO) reference standards.

These materials support pharmaceutical research and development, product development, ANDA and DMF submissions, quality control (QC), analytical method development and validation, stability studies, impurity identification, and genotoxic impurity assessment.

Our Decitabine-related reference standards are thoroughly characterized using advanced analytical techniques and are supplied with comprehensive Certificates of Analysis (COA) and supporting analytical data from our USFDA certified, ISO 17025 and ISO 17034 accredited Lab, to meet global regulatory expectations. EP and USP traceable reference standards can also be provided upon request, subject to availability. Simson is also a provider of EP and USP traceable standards. To ensure consistent quality and reliability, our reference standards are periodically re-tested according to established quality management procedures.

Pharmaceutical Reference Standards / Impurity Standards

Decitabine
D-2`-Deoxyribopyranosyl-3-guanylurea (alpha/beta-Mixture)
Decitabine Deformyl Impurity Formate Salt
Decitabine Deformyl Impurity (Mixture of Diastereomers)
Decitabine Alpha Isomer Impurity
Decitabine RC A
Azacitidine Related Compound A
5-Azacytosine Hydrate
Decitabine Related Compound C
Decitabine Related Compound B
Decitabine Impurity 2(alpha Isomer )
Decitabine Related Compound D
Mixture of Decitabine Related Compound B and C
Methyl 4-Methylbenzoate
Methyl 2-deoxy-beta-D-erythro-pentopyranoside
Decitabine Mixture of Alpha And Beta Isomers
Decitabine Related Compound A (Mixture of Isomers)
Decitabine impurity DEC 2B (acetic acid 3-acetoxy-5-methoxytetrahydrofuran-2-yl methyl ester)
Decitabine impurity DEC 1B(2-hydroxymethyl-5-methoxytetrahydrofuran-3-ol)
Decitabine EP Impurity B
Decitabine Di-Toluoyl Impurity
2-Doxy-D-Ribose
D-2`-Deoxyribopyranosyl-3-guanylurea (alpha/beta-Mixture)
2-Deoxy-D-erythro-pentopyranosylchlorideBis(4-methylbenzoate)
Decitabine 6-Methyl Impurity
Decitabine Impurity 7
N-Phenyl-2-deoxy-D-glucosylamine
Decitabine Impurity 35
Decitabine Impurity 18
Decitabine Impurity 25
1-beta-D-2-deoxyribopyranosyl-3-guanylurea
Decitabine 5`-monoacetyl impurity
Decitabine 3`-monoacetyl impurity
N-Formyl Decitabine
(2R,3R,5R)-5-(4-amino-2-oxo-1,3,5-triazin-1(2H)-yl)-2-(hydroxyl methyl)tetrahydrofuran-3-yl-4-methylbenzoate
Decitabine Impurity 2
4-Amino-1-(4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3,5-triazin-2(1H)-on
p-Chlorobenzoyl Decitabine Beta
p-Chlorobenzoyl Decitabine Alpha
Decitabine Ring-Opening Impurity
Decitabine Deformyl Impurity Formic Acid
Decitabine Impurity 43
Decitabine Impurity 37
Decitabine Impurity 28
Decitabine Impurity 36
D-formyl Impurity Related Compound 3
Decitabine Impurity 5
Decitabine Impurity 9
Decitabine Impurity 8