Nitrosamines and N-nitroso compounds
What are nitrosamines?
Formation of nitrosamines is carried out through a simple reaction in the presence of secondary, tertiary, or quaternary amines with a nitrating agent under acidic reaction conditions. However, it was concluded that the possibility for nitrosamine impurity content was broader than simply the concurrent presence of nitrites and amines in the synthesis of the active pharmaceutical ingredient (API).
Simson is specialized in delivering nitroso amine impurities with Certificate of analysis along with characterization and purity. We are equipped with ultra-high performance LC-MS and Triple triple quadrupole MS Mass Spectrometers for accurate determination of purity.
SimSon Pharma provides synthetic and analytical services for custom synthesis of Drug impurities,peptides,metabolites and nitrososmine impurities from miligram to multi gram level.