Brinzolamide Related Compounds & Impurities

Brinzolamide is a topical carbonic anhydrase inhibitor formulated as an ophthalmic suspension for intraocular pressure management in glaucoma.

Simson Pharma Limited along with its subsidiary offices Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) is a trusted manufacturer and supplier of high-quality pharmaceutical reference standards, offering a comprehensive portfolio of Brinzolamide reference standards, pharmacopeial and non-pharmacopeial Brinzolamide impurities, related compounds, related substances, metabolites, stable isotope-labelled compounds, deuterium labelled compounds and nitrosamine (N-NO) reference standards.

These materials support pharmaceutical research and development, product development, ANDA and DMF submissions, quality control (QC), analytical method development and validation, stability studies, impurity identification, and genotoxic impurity assessment.

Our Brinzolamide-related reference standards are thoroughly characterized using advanced analytical techniques and are supplied with comprehensive Certificates of Analysis (COA) and supporting analytical data from our USFDA certified, ISO 17025 and ISO 17034 accredited Lab, to meet global regulatory expectations. EP and USP traceable reference standards can also be provided upon request, subject to availability. Simson is also a provider of EP and USP traceable standards. To ensure consistent quality and reliability, our reference standards are periodically re-tested according to established quality management procedures.

Pharmaceutical Reference Standards / Impurity Standards

Brinzolamide
Brinzolamide
  • CAT. No.B360000
  • CAS. No.138890-62-7
  • Mol. F.C12H21N3O5S3
  • Mol. W.383.51 g/mol
  • Stock Status:Instock
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(S)-Brinzolamide
(S)-Brinzolamide
  • CAT. No.B360001
  • CAS. No.154127-19-2
  • Mol. F.C12H21N3O5S3
  • Mol. W.383.51 g/mol
  • Stock Status:Instock
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N-Desethyl Brinzolamide
N-Desethyl Brinzolamide
  • CAT. No.B360002
  • CAS. No.404034-55-5
  • Mol. F.C10H17N3O5S3
  • Mol. W.355.45 g/mol
  • Stock Status:Custom Synthesis
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Brinzolamide Impurity B
Brinzolamide Impurity B
  • CAT. No.B360003
  • CAS. No.404034-55-5
  • Mol. F.C10H17N3O5S3
  • Mol. W.355.46 g/mol
  • Stock Status:Custom Synthesis
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Brinzolamide Methane Sulphonyl Impurity
Brinzolamide Methane Sulphonyl Impurity
  • CAT. No.B360004
  • CAS. No.NA
  • Mol. F.C13H23N3O7S4
  • Mol. W.461.60 g/mol
  • Stock Status:Instock
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Brinzolamide Isopropyl Impurity
Brinzolamide Isopropyl Impurity
  • CAT. No.B360005
  • CAS. No.NA
  • Mol. F.C13H23N3O5S3
  • Mol. W.397.53 g/mol
  • Stock Status:Instock
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(S)-6-Chloro-4-hydroxy-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine 1,1-Dioxide
(S)-6-Chloro-4-hydroxy-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine 1,1-Dioxide
  • CAT. No.B360006
  • CAS. No.160982-16-1
  • Mol. F.C6H6ClNO3S2
  • Mol. W.239.70 g/mol
  • Stock Status:Custom Synthesis
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O-Desmethyl Brinzolamide
O-Desmethyl Brinzolamide
  • CAT. No.B360007
  • CAS. No.186377-56-0
  • Mol. F.C11H19N3O5S3
  • Mol. W.369.48 g/mol
  • Stock Status:Custom Synthesis
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Brinzolamide Impurity
Brinzolamide Impurity
  • CAT. No.B360008
  • CAS. No.165117-54-4
  • Mol. F.C10H16N2O6S3
  • Mol. W.356.44 g/mol
  • Stock Status:Custom Synthesis
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Brinzolamide Impurity 4
Brinzolamide Impurity 4
  • CAT. No.B360009
  • CAS. No.154127-41-0
  • Mol. F.C10H14N2O6S3
  • Mol. W.354.42 g/mol
  • Stock Status:Custom Synthesis
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Brinzolamide Racemc mixture(mixture of S&R isomer)
Brinzolamide Racemc mixture(mixture of S&R isomer)
  • CAT. No.B360012
  • CAS. No.138890-50-3
  • Mol. F.C12H21N3O5S3
  • Mol. W.383.51 g/mol
  • Stock Status:Custom Synthesis
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Brinzolamide Impurity D
Brinzolamide Impurity D
  • CAT. No.B360013
  • CAS. No.154127-42-1
  • Mol. F.C10H16N2O6S3
  • Mol. W.356.44 g/mol
  • Stock Status:Instock
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(S)-2-(3-methoxypropyl)-6-(N-(methylsulfonyl)sulfamoyl)-1,1-dioxido-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazin-4-ylmethanesulfonate
(S)-2-(3-methoxypropyl)-6-(N-(methylsulfonyl)sulfamoyl)-1,1-dioxido-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazin-4-ylmethanesulfonate
  • CAT. No.B360014
  • CAS. No.NA
  • Mol. F.C12H20N2O10S5
  • Mol. W.512.62 g/mol
  • Stock Status:Custom Synthesis
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(R)-4-(ethylamino)-2-(3-methoxypropyl)-N-(methylsulfonyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide1,1-dioxide
(R)-4-(ethylamino)-2-(3-methoxypropyl)-N-(methylsulfonyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide1,1-dioxide
  • CAT. No.B360015
  • CAS. No.NA
  • Mol. F.C13H23N3O7S4
  • Mol. W.461.60 g/mol
  • Stock Status:Custom Synthesis
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(S)-4-hydroxy-2-(3-methoxypropyl)-N-(methylsulfonyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide1,1-dioxide
(S)-4-hydroxy-2-(3-methoxypropyl)-N-(methylsulfonyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide1,1-dioxide
  • CAT. No.B360016
  • CAS. No.NA
  • Mol. F.C11H18N2O8S4
  • Mol. W.434.53 g/mol
  • Stock Status:Custom Synthesis
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(S,4R)-N-ethyl-2-(3-methoxypropyl)-6-sulfamoyl-3,4-dihydro-2H-thieno-[3,2-e][1,2]thiazin-4-amine oxide 1,1-dioxide
(S,4R)-N-ethyl-2-(3-methoxypropyl)-6-sulfamoyl-3,4-dihydro-2H-thieno-[3,2-e][1,2]thiazin-4-amine oxide 1,1-dioxide
  • CAT. No.B360017
  • CAS. No.NA
  • Mol. F.C12H21N3O6S3
  • Mol. W.399.51 g/mol
  • Stock Status:Custom Synthesis
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(R,4S)-N-ethyl-2-(3-methoxypropyl)-6-sulfamoyl-3,4-dihydro-2H-thieno-[3,2-e][1,2]thiazin-4-amine oxide 1,1-dioxide
(R,4S)-N-ethyl-2-(3-methoxypropyl)-6-sulfamoyl-3,4-dihydro-2H-thieno-[3,2-e][1,2]thiazin-4-amine oxide 1,1-dioxide
  • CAT. No.B360018
  • CAS. No.NA
  • Mol. F.C12H21N3O6S3
  • Mol. W.399.51 g/mol
  • Stock Status:Custom Synthesis
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Brinzolamide Impurity C
Brinzolamide Impurity C
  • CAT. No.B360019
  • CAS. No.186377-56-0
  • Mol. F.C19H27N3O7S4
  • Mol. W.369.48 g/mol
  • Stock Status:Under Synthesis
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Brinzolamide Impurity C Trifluoroacetate Salt
Brinzolamide Impurity C Trifluoroacetate Salt
  • CAT. No.B360019A
  • CAS. No.NA
  • Mol. F.C19H27N3O7S4.C2F3O2H
  • Mol. W.651.72 g/mol
  • Stock Status:Instock
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1-(2-(Benzylthio)-5-chlorothiophen-3-yl)ethanone
1-(2-(Benzylthio)-5-chlorothiophen-3-yl)ethanone
  • CAT. No.B360024
  • CAS. No.160982-09-2
  • Mol. F.C13H11ClOS2
  • Mol. W.282.81 g/mol
  • Stock Status:Custom Synthesis
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2-(3-methoxypropyl)-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide
2-(3-methoxypropyl)-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide
  • CAT. No.B360025
  • CAS. No.NA
  • Mol. F.C10H14N2O5S3
  • Mol. W.338.42 g/mol
  • Stock Status:Custom Synthesis
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Brinzolamide N-Ethanol Impurity
Brinzolamide N-Ethanol Impurity
  • CAT. No.B360026
  • CAS. No.NA
  • Mol. F.C14H25N3O6S3
  • Mol. W.427.56 g/mol
  • Stock Status:Custom Synthesis
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2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide
2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide
  • CAT. No.B360027
  • CAS. No.NA
  • Mol. F.C10H16N2O5S3
  • Mol. W.340.44 g/mol
  • Stock Status:Custom Synthesis
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(R)-4-(Ethylamino)-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonic acid 1,1-dioxide
(R)-4-(Ethylamino)-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonic acid 1,1-dioxide
  • CAT. No.B360028
  • CAS. No.NA
  • Mol. F.C12H20N2O6S3
  • Mol. W.384.49 g/mol
  • Stock Status:Custom Synthesis
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Brinzolamide N-Nitroso
Brinzolamide N-Nitroso
  • CAT. No.B360029
  • CAS. No.NA
  • Mol. F.C12H20N4O6S3
  • Mol. W.412.51 g/mol
  • Stock Status:Limited Stock
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2-(2-methoxyethyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide
2-(2-methoxyethyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide
  • CAT. No.B360030
  • CAS. No.NA
  • Mol. F.C9H14N2O5S3
  • Mol. W.326.41 g/mol
  • Stock Status:Custom Synthesis
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Brinzolamide Impurity G
Brinzolamide Impurity G
  • CAT. No.B360031
  • CAS. No.NA
  • Mol. F.C11H20ClN3O5S3
  • Mol. W.405.94 g/mol
  • Stock Status:Custom Synthesis
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Desethyl Brinzolamide
Desethyl Brinzolamide
  • CAT. No.B360033
  • CAS. No.2109554-77-8
  • Mol. F.C10H17N3O5S3
  • Mol. W.355.45 g/mol
  • Stock Status:Custom Synthesis
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Brinzolamide Tosyl Impurity
Brinzolamide Tosyl Impurity
  • CAT. No.B360034
  • CAS. No.NA
  • Mol. F.C19H27N3O7S4
  • Mol. W.537.69 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso O-Desmethyl Brinzolamide
N-Nitroso O-Desmethyl Brinzolamide
  • CAT. No.B360035
  • CAS. No.NA
  • Mol. F.C11H18N4O6S3
  • Mol. W.398.48 g/mol
  • Stock Status:Custom Synthesis
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(R)-4-(Ethylamino)-2-methyl-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide
(R)-4-(Ethylamino)-2-methyl-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide
  • CAT. No.B360036
  • CAS. No.138890-58-1
  • Mol. F.C9H15N3O4S3
  • Mol. W.325.43 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Brinzolamide Impurity 30
N-Nitroso Brinzolamide Impurity 30
  • CAT. No.B360037
  • CAS. No.NA
  • Mol. F.C10H15N3O7S3
  • Mol. W.385.44 g/mol
  • Stock Status:Custom Synthesis
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Brinzolamide Related Compound B
Brinzolamide Related Compound B
  • CAT. No.B360038
  • CAS. No.NA
  • Mol. F.C10H17N3O5S3.C2H2O4
  • Mol. W.445.49 g/mol
  • Stock Status:Instock
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Brinzolamide Chloro Impurity
Brinzolamide Chloro Impurity
  • CAT. No.B360039
  • CAS. No.160982-13-8
  • Mol. F.C10H14ClNO4S2
  • Mol. W.311.80 g/mol
  • Stock Status:Custom Synthesis
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Brinzolamide Deschloro Impurity
Brinzolamide Deschloro Impurity
  • CAT. No.B360040
  • CAS. No.1029324-91-1
  • Mol. F.C10H15NO4S2
  • Mol. W.277.40 g/mol
  • Stock Status:Custom Synthesis
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Brinzolamide Tosyl Impurity (S-Isomer)
Brinzolamide Tosyl Impurity (S-Isomer)
  • CAT. No.B360041
  • CAS. No.NA
  • Mol. F.C19H27N3O7S4
  • Mol. W.537.69 g/mol
  • Stock Status:Custom Synthesis
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Brinzolamide Chloro Impurity R-isomer
Brinzolamide Chloro Impurity R-isomer
  • CAT. No.B360042
  • CAS. No.NA
  • Mol. F.C10H14ClNO4S2
  • Mol. W.311.81 g/mol
  • Stock Status:Custom Synthesis
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Brinzolamide Impurity 20
Brinzolamide Impurity 20
  • CAT. No.B360043
  • CAS. No.NA
  • Mol. F.C6H6ClNO3S2
  • Mol. W.239.70 g/mol
  • Stock Status:Custom Synthesis
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Brinzolamide Impurity 8
Brinzolamide Impurity 8
  • CAT. No.B360044
  • CAS. No.NA
  • Mol. F.C19H30N6O8S6
  • Mol. W.662.87 g/mol
  • Stock Status:Custom Synthesis
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Brinzolamide Impurity 1
Brinzolamide Impurity 1
  • CAT. No.B360045
  • CAS. No.NA
  • Mol. F.C18H30N4O6S3
  • Mol. W.494.65 g/mol
  • Stock Status:Custom Synthesis
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Brinzolamide Impurity 5
Brinzolamide Impurity 5
  • CAT. No.B360046
  • CAS. No.160982-11-6
  • Mol. F.C6H5BrClNO3S2
  • Mol. W.318.60 g/mol
  • Stock Status:Custom Synthesis
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Isotope Labelled Compounds

Brinzolamide D5
Brinzolamide D5
  • CAT. No.B360021
  • CAS. No.1217651-02-9
  • Mol. F.C12H16D5N3O5S3
  • Mol. W.388.54 g/mol
  • Stock Status:Custom Synthesis
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Brinzolamide D5 Hydrochloride
Brinzolamide D5 Hydrochloride
  • CAT. No.B360021A
  • CAS. No.NA
  • Mol. F.C12H16D5N3O5S3.HCl
  • Mol. W.425.00 g/mol
  • Stock Status:Instock
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