Bosentan hydrate Related Compounds & Impurities

Bosentan Hydrate is an oral dual endothelin-A/B receptor antagonist that reduces pulmonary vascular resistance, used as a foundational therapy for pulmonary arterial hypertension.

Simson Pharma Limited along with its subsidiary offices Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) is a trusted manufacturer and supplier of high-quality pharmaceutical reference standards, offering a comprehensive portfolio of Bosentan hydrate reference standards, pharmacopeial and non-pharmacopeial Bosentan hydrate impurities, related compounds, related substances, metabolites, stable isotope-labelled compounds, deuterium labelled compounds and nitrosamine (N-NO) reference standards.

These materials support pharmaceutical research and development, product development, ANDA and DMF submissions, quality control (QC), analytical method development and validation, stability studies, impurity identification, and genotoxic impurity assessment.

Our Bosentan hydrate-related reference standards are thoroughly characterized using advanced analytical techniques and are supplied with comprehensive Certificates of Analysis (COA) and supporting analytical data from our USFDA certified, ISO 17025 and ISO 17034 accredited Lab, to meet global regulatory expectations. EP and USP traceable reference standards can also be provided upon request, subject to availability. Simson is also a provider of EP and USP traceable standards. To ensure consistent quality and reliability, our reference standards are periodically re-tested according to established quality management procedures.

Pharmaceutical Reference Standards / Impurity Standards

Bosentan Monohydrate
Bosentan Monohydrate
  • CAT. No.B450000
  • CAS. No.157212-55-0
  • Mol. F.C27H29N5O6S.H2O
  • Mol. W.569.63 g/mol
  • Stock Status:Instock
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O-Deshydroxyethyl Bosentan
O-Deshydroxyethyl Bosentan
  • CAT. No.B450001
  • CAS. No.174227-14-6
  • Mol. F.C25H25N5O5S
  • Mol. W.507.56 g/mol
  • Stock Status:Instock
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Bosentan USP Related Compound A
Bosentan USP Related Compound A
  • CAT. No.B450002
  • CAS. No.150727-06-3
  • Mol. F.C25H24ClN5O4S
  • Mol. W.526.01 g/mol
  • Stock Status:Instock
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Bosentan Chlorosulfonamide Cesium Salt
Bosentan Chlorosulfonamide Cesium Salt
  • CAT. No.B450002A
  • CAS. No.NA
  • Mol. F.C25H23ClCsN5O4S
  • Mol. W.657.90 g/mol
  • Stock Status:Instock
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Bosentan USP Related Compound D
Bosentan USP Related Compound D
  • CAT. No.B450003
  • CAS. No.150728-13-5
  • Mol. F.C15H10Cl2N4O2
  • Mol. W.349.17 g/mol
  • Stock Status:Instock
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Bosentan Dimer Impurity
Bosentan Dimer Impurity
  • CAT. No.B450004
  • CAS. No.1097263-60-9
  • Mol. F.C52H52N10O10S2
  • Mol. W.1041.16 g/mol
  • Stock Status:Instock
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Bosentan USP Related Compound E
Bosentan USP Related Compound E
  • CAT. No.B450006
  • CAS. No.6292-59-7
  • Mol. F.C10H15NO2S
  • Mol. W.213.30 g/mol
  • Stock Status:Instock
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Bosentan Monohydrate Ethyl Ester Impurity
Bosentan Monohydrate Ethyl Ester Impurity
  • CAT. No.B450008
  • CAS. No.NA
  • Mol. F.NA
  • Mol. W.NA
  • Stock Status:Custom Synthesis
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N,N'-[5-(2-methoxyphenoxy)[2,2'-bipyrimidine]-4,6-diyl]bis[4-(1,1-dimethylethyl)benzenesulfonamide]
N,N'-[5-(2-methoxyphenoxy)[2,2'-bipyrimidine]-4,6-diyl]bis[4-(1,1-dimethylethyl)benzenesulfonamide]
  • CAT. No.B450010
  • CAS. No.1218951-81-5
  • Mol. F.C35H38N6O6S2
  • Mol. W.702.84 g/mol
  • Stock Status:Custom Synthesis
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O-Desmethyl Bosentan
O-Desmethyl Bosentan
  • CAT. No.B450011
  • CAS. No.253688-61-8
  • Mol. F.CHNOS
  • Mol. W.537.59 g/mol
  • Stock Status:Instock
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Bosentan Impurity 9
Bosentan Impurity 9
  • CAT. No.B450012
  • CAS. No.1177447-87-8
  • Mol. F. C21H23ClN4O4
  • Mol. W.430.88 g/mol
  • Stock Status:Custom Synthesis
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Bosentan hydroxyethoxy Ethyl
Bosentan hydroxyethoxy Ethyl
  • CAT. No.B450013
  • CAS. No.NA
  • Mol. F.C29H33N5O7S
  • Mol. W.595.67 g/mol
  • Stock Status:Instock
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4-(tert-butyl)-N-((tertbutyl)phenyl)sulfonyl)benzenesulfonamide
4-(tert-butyl)-N-((tertbutyl)phenyl)sulfonyl)benzenesulfonamide
  • CAT. No.B450014
  • CAS. No.1355251-10-3
  • Mol. F.C20H27NO4S2
  • Mol. W.409.56 g/mol
  • Stock Status:Custom Synthesis
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2-Methyl-2-phenylpropanoic acid
2-Methyl-2-phenylpropanoic acid
  • CAT. No.B450015
  • CAS. No.826-55-1
  • Mol. F.C10H12O2
  • Mol. W.164.20 g/mol
  • Stock Status:Instock
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Bosentan Impurity 5
Bosentan Impurity 5
  • CAT. No.B450016
  • CAS. No.193013-72-8
  • Mol. F.C10H15NO2S
  • Mol. W.213.30 g/mol
  • Stock Status:Custom Synthesis
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Bosentan Impurity 3
Bosentan Impurity 3
  • CAT. No.B450017
  • CAS. No.1257099-43-6
  • Mol. F.C29H33N5O7S
  • Mol. W.595.67 g/mol
  • Stock Status:Custom Synthesis
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Bosentan Impurity 4
Bosentan Impurity 4
  • CAT. No.B450018
  • CAS. No.1257099-44-7
  • Mol. F.C27H27N5O5S
  • Mol. W.533.6 g/mol
  • Stock Status:Custom Synthesis
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4-tert-butylbenzenesulfonic acid
4-tert-butylbenzenesulfonic acid
  • CAT. No.B450019
  • CAS. No.1133-17-1
  • Mol. F.C10H14O3S
  • Mol. W.214.28 g/mol
  • Stock Status:Custom Synthesis
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Bosentan Related Compound B
Bosentan Related Compound B
  • CAT. No.B450023
  • CAS. No.174227-14-6
  • Mol. F.C25H25N5O5S
  • Mol. W.507.56 g/mol
  • Stock Status:Instock
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Bosentan Related Compound 4
Bosentan Related Compound 4
  • CAT. No.B450025
  • CAS. No.1160515-53-6
  • Mol. F.C29H31N5O7S
  • Mol. W.593.66 g/mol
  • Stock Status:Custom Synthesis
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4-tert-butyl-N-[6-ethoxy-5-(2-methoxyphenoxy)-[2,2`-bipyrimidin]-4-yl]benzene-1-sulfonamide
4-tert-butyl-N-[6-ethoxy-5-(2-methoxyphenoxy)-[2,2`-bipyrimidin]-4-yl]benzene-1-sulfonamide
  • CAT. No.B450026
  • CAS. No.157415-45-7
  • Mol. F.C27H29N5O5S
  • Mol. W.535.61 g/mol
  • Stock Status:Instock
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Bosentan Impurity 6
Bosentan Impurity 6
  • CAT. No.B450027
  • CAS. No.1413393-94-8
  • Mol. F.C12H18O4S
  • Mol. W.258.34 g/mol
  • Stock Status:Custom Synthesis
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Bosentan Chloro Impurity
Bosentan Chloro Impurity
  • CAT. No.B450028
  • CAS. No.1855932-53-4
  • Mol. F.C27H28ClN5O5S
  • Mol. W.570.06 g/mol
  • Stock Status:Custom Synthesis
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Bosentan Impurity 1
Bosentan Impurity 1
  • CAT. No.B450029
  • CAS. No.150726-89-9
  • Mol. F.C12H14O6
  • Mol. W.254.24 g/mol
  • Stock Status:Custom Synthesis
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Bosentan Impurity 2
Bosentan Impurity 2
  • CAT. No.B450030
  • CAS. No.150728-12-4
  • Mol. F.C15H12N4O4
  • Mol. W.312.28 g/mol
  • Stock Status:Custom Synthesis
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Bosentan Impurity 7
Bosentan Impurity 7
  • CAT. No.B450031
  • CAS. No.1268612-27-6
  • Mol. F.C15H11ClN4O3
  • Mol. W.330.73 g/mol
  • Stock Status:Custom Synthesis
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Bosentan Impurity 8
Bosentan Impurity 8
  • CAT. No.B450032
  • CAS. No.NA
  • Mol. F.C9H8N4O3
  • Mol. W.220.18 g/mol
  • Stock Status:Custom Synthesis
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Bosentan Impurity 10
Bosentan Impurity 10
  • CAT. No.B450033
  • CAS. No.2040390-30-3
  • Mol. F.C8H5ClN4O2
  • Mol. W.224.60 g/mol
  • Stock Status:Custom Synthesis
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Bosentan Impurity 11
Bosentan Impurity 11
  • CAT. No.B450034
  • CAS. No.2040390-37-0
  • Mol. F.C8H3Cl3N4
  • Mol. W.261.50 g/mol
  • Stock Status:Custom Synthesis
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Bosentan Impurity 12
Bosentan Impurity 12
  • CAT. No.B450035
  • CAS. No.301646-59-3
  • Mol. F.C25H24ClN5O4S.K
  • Mol. W.565.11 g/mol
  • Stock Status:Custom Synthesis
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Bosentan Impurity 13
Bosentan Impurity 13
  • CAT. No.B450036
  • CAS. No.1257099-41-4
  • Mol. F.C22H27N5O6S
  • Mol. W.489.54 g/mol
  • Stock Status:Custom Synthesis
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Bosentan Impurity 14
Bosentan Impurity 14
  • CAT. No.B450037
  • CAS. No.1160515-53-6
  • Mol. F.C28H29N5O7S
  • Mol. W.579.62 g/mol
  • Stock Status:Custom Synthesis
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Bosentan Impurity 15
Bosentan Impurity 15
  • CAT. No.B450038
  • CAS. No.301646-60-6
  • Mol. F.C31H37N5O6S
  • Mol. W.607.72 g/mol
  • Stock Status:Custom Synthesis
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Bosentan Impurity 16
Bosentan Impurity 16
  • CAT. No.B450039
  • CAS. No.NA
  • Mol. F.C31H37N5O6S
  • Mol. W.607.72 g/mol
  • Stock Status:Instock
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Bosentan Impurity 17
Bosentan Impurity 17
  • CAT. No.B450040
  • CAS. No.NA
  • Mol. F.C31H37N5O6S
  • Mol. W.607.72 g/mol
  • Stock Status:Custom Synthesis
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Isotope Labelled Compounds

Bosentan-D4
Bosentan-D4
  • CAT. No.B450005
  • CAS. No.1065472-77-6
  • Mol. F.C27H25D4N5O6S
  • Mol. W.555.64 g/mol
  • Stock Status:Instock
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Bosentan 13C6
Bosentan 13C6
  • CAT. No.B450024
  • CAS. No.NA
  • Mol. F.C21C613H29N5O6S
  • Mol. W.557.57 g/mol
  • Stock Status:Custom Synthesis
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