Bendamustine Related Compounds & Impurities

Bendamustine is a bifunctional alkylating agent with a nitrogen-mustard moiety and benzimidazole ring, used for chronic lymphocytic leukaemia and indolent lymphomas.

Simson Pharma Limited along with its subsidiary offices Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) is a trusted manufacturer and supplier of high-quality pharmaceutical reference standards, offering a comprehensive portfolio of Bendamustine reference standards, pharmacopeial and non-pharmacopeial Bendamustine impurities, related compounds, related substances, metabolites, stable isotope-labelled compounds, deuterium labelled compounds and nitrosamine (N-NO) reference standards.

These materials support pharmaceutical research and development, product development, ANDA and DMF submissions, quality control (QC), analytical method development and validation, stability studies, impurity identification, and genotoxic impurity assessment.

Our Bendamustine-related reference standards are thoroughly characterized using advanced analytical techniques and are supplied with comprehensive Certificates of Analysis (COA) and supporting analytical data from our USFDA certified, ISO 17025 and ISO 17034 accredited Lab, to meet global regulatory expectations. EP and USP traceable reference standards can also be provided upon request, subject to availability. Simson is also a provider of EP and USP traceable standards. To ensure consistent quality and reliability, our reference standards are periodically re-tested according to established quality management procedures.

Pharmaceutical Reference Standards / Impurity Standards

Bendamustine
Bendamustine
  • CAT. No.B040000A
  • CAS. No.16506-27-7
  • Mol. F.C16H21Cl2N3O2
  • Mol. W.358.26 g/mol
  • Stock Status:Custom Synthesis
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Bendamustine Hydrochloride monohydrate
Bendamustine Hydrochloride monohydrate
  • CAT. No.B040000C
  • CAS. No.1374784-02-7
  • Mol. F.C16H24Cl3N3O3
  • Mol. W.412.70 g/mol
  • Stock Status:Instock
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Monohydroxy Bendamustine Impurity
Monohydroxy Bendamustine Impurity
  • CAT. No.B040001
  • CAS. No.109882-27-1
  • Mol. F.C16H22ClN3O3
  • Mol. W.339.82 g/mol
  • Stock Status:Instock
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Bendamustine Related Compound A
Bendamustine Related Compound A
  • CAT. No.B040002
  • CAS. No.109882-30-6
  • Mol. F.C16H23N3O4
  • Mol. W.321.37 g/mol
  • Stock Status:Instock
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Bendamustine Impurity 19
Bendamustine Impurity 19
  • CAT. No.B040003
  • CAS. No.3543-73-5
  • Mol. F.C14H19N3O2
  • Mol. W.261.32 g/mol
  • Stock Status:Instock
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Bendamustine Related Compound H
Bendamustine Related Compound H
  • CAT. No.B040004
  • CAS. No.1228551-91-4
  • Mol. F.C32H41Cl3N6O4
  • Mol. W.680.06 g/mol
  • Stock Status:Instock
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Bendamustine Deschloro Dimer Impurity
Bendamustine Deschloro Dimer Impurity
  • CAT. No.B040005
  • CAS. No.1391052-61-1
  • Mol. F.C32H44N6O7
  • Mol. W.624.73 g/mol
  • Stock Status:Custom Synthesis
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Bendamustine Related Impurity 8
Bendamustine Related Impurity 8
  • CAT. No.B040006
  • CAS. No.NA
  • Mol. F.C32H42Cl2N6O5
  • Mol. W.661.63 g/mol
  • Stock Status:Custom Synthesis
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Bendamustine D-Mannitol Ester
Bendamustine D-Mannitol Ester
  • CAT. No.B040007
  • CAS. No.1869075-89-7
  • Mol. F.C22H33Cl2N3O7
  • Mol. W.522.43 g/mol
  • Stock Status:Instock
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Bendamustine Related Compound B
Bendamustine Related Compound B
  • CAT. No.B040008
  • CAS. No.1228552-02-0
  • Mol. F.C16H21N3O3
  • Mol. W.303.36 g/mol
  • Stock Status:Instock
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Bendamustine Deschloroethyl Acid Impurity
Bendamustine Deschloroethyl Acid Impurity
  • CAT. No.B040009
  • CAS. No.1219709-86-0
  • Mol. F.C14H18ClN3O2
  • Mol. W.295.76 g/mol
  • Stock Status:Instock
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Bendamustine Ethyl Ester Impurity
Bendamustine Ethyl Ester Impurity
  • CAT. No.B040010
  • CAS. No.87475-54-5
  • Mol. F.C18H25Cl2N3O2
  • Mol. W.386.32 g/mol
  • Stock Status:Instock
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Bendamustine Ethyl Ester Impurity Hydrate
Bendamustine Ethyl Ester Impurity Hydrate
  • CAT. No.B040010A
  • CAS. No.87475-54-5 (Free base)
  • Mol. F.C18H25Cl2N3O2.H2O
  • Mol. W.404.32 g/mol
  • Stock Status:Instock
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Bendamustine Dihydroxy Ester
Bendamustine Dihydroxy Ester
  • CAT. No.B040011
  • CAS. No.3543-74-6
  • Mol. F.C18H27N3O4
  • Mol. W.349.4 g/mol
  • Stock Status:Instock
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Bendamustine USP Related Compound G
Bendamustine USP Related Compound G
  • CAT. No.B040012
  • CAS. No.191939-34-1
  • Mol. F.C16H20ClN3O2S
  • Mol. W.353.87 g/mol
  • Stock Status:Instock
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Bendamustine methyl Ester Impurity
Bendamustine methyl Ester Impurity
  • CAT. No.B040013
  • CAS. No.109882-25-9
  • Mol. F.C17H23Cl2N3O2
  • Mol. W.372.29 g/mol
  • Stock Status:Instock
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Bendamustine Isopropyl Ester
Bendamustine Isopropyl Ester
  • CAT. No.B040014
  • CAS. No.1313020-25-5
  • Mol. F.C19H27Cl2N3O2
  • Mol. W.400.34 g/mol
  • Stock Status:Instock
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Bendamustine Isopropyl Ester Impurity
Bendamustine Isopropyl Ester Impurity
  • CAT. No.B040015
  • CAS. No.1797008-41-3
  • Mol. F.C19H28ClN3O3
  • Mol. W.381.90 g/mol
  • Stock Status:Custom Synthesis
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Bendamustine Impurity 13
Bendamustine Impurity 13
  • CAT. No.B040017
  • CAS. No.914626-65-6
  • Mol. F.C19H18N6O4
  • Mol. W.394.38 g/mol
  • Stock Status:Custom Synthesis
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Bendamustine Impurity 16
Bendamustine Impurity 16
  • CAT. No.B040018
  • CAS. No.847588-86-7
  • Mol. F.C19H22N6
  • Mol. W.334.43 g/mol
  • Stock Status:Custom Synthesis
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Bendamustine Mannitol Ester
Bendamustine Mannitol Ester
  • CAT. No.B040021
  • CAS. No.1869075-89-7
  • Mol. F.C22H33Cl3N3O8
  • Mol. W.538.42 g/mol
  • Stock Status:Custom Synthesis
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Bendamustine Glycerol Ester
Bendamustine Glycerol Ester
  • CAT. No.B040022
  • CAS. No.NA
  • Mol. F.C19H27Cl2N3O4
  • Mol. W.432.34 g/mol
  • Stock Status:Instock
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Bendamustine Impurity 17
Bendamustine Impurity 17
  • CAT. No.B040023
  • CAS. No.NA
  • Mol. F.C18H24ClN3O4
  • Mol. W.381.85 g/mol
  • Stock Status:Custom Synthesis
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Deschloroethyl Bendamustine Hydrochloride
Deschloroethyl Bendamustine Hydrochloride
  • CAT. No.B040024
  • CAS. No.1797881-48-1
  • Mol. F.C14H19Cl2N3O2
  • Mol. W.332.23 g/mol
  • Stock Status:Instock
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N-DesmethylBendamustine
N-DesmethylBendamustine
  • CAT. No.B040025
  • CAS. No.41515-13-3
  • Mol. F.C15H19Cl2N3O2
  • Mol. W.344.24 g/mol
  • Stock Status:Custom Synthesis
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4-(5-((2-Chloroethyl)(2-((2,3-dihydroxypropyl)thio)ethyl)amino)-1-methyl-1H-benzo(d)imidazol-2-yl)butanoic acid
4-(5-((2-Chloroethyl)(2-((2,3-dihydroxypropyl)thio)ethyl)amino)-1-methyl-1H-benzo(d)imidazol-2-yl)butanoic acid
  • CAT. No.B040026
  • CAS. No.NA
  • Mol. F.C19H28ClN3O4S
  • Mol. W.429.96 g/mol
  • Stock Status:Custom Synthesis
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Bendamustine Propylene Glycol Ester 1 and 2
Bendamustine Propylene Glycol Ester 1 and 2
  • CAT. No.B040027
  • CAS. No.NA
  • Mol. F.C38H54Cl4N6O6
  • Mol. W.832.70 g/mol
  • Stock Status:Instock
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Bendamustine Monohydroxy Acid Ethyl Ester
Bendamustine Monohydroxy Acid Ethyl Ester
  • CAT. No.B040028
  • CAS. No.898224-95-8
  • Mol. F.C18H26ClN3O3
  • Mol. W.367.87 g/mol
  • Stock Status:Custom Synthesis
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Bendamustine Related Compound E
Bendamustine Related Compound E
  • CAT. No.B040028A
  • CAS. No.109882-27-1
  • Mol. F.C16H22ClN3O3
  • Mol. W.339.82 g/mol
  • Stock Status:Custom Synthesis
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Bendamustine Dihydroxy
Bendamustine Dihydroxy
  • CAT. No.B040030
  • CAS. No.109882-29-3
  • Mol. F.C16H24N3O4Cl
  • Mol. W.357.83 g/mol
  • Stock Status:Instock
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Bendamustine USP Related Compound G
Bendamustine USP Related Compound G
  • CAT. No.B040031
  • CAS. No.NA
  • Mol. F.C16H20ClN3O2S.HCl
  • Mol. W.390.33 g/mol
  • Stock Status:Custom Synthesis
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Bendamustine Impurity 8
Bendamustine Impurity 8
  • CAT. No.B040032
  • CAS. No.41939-61-1
  • Mol. F.C7H9N3O2
  • Mol. W.167.17 g/mol
  • Stock Status:Instock
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Bendamustine Nitro Isopropyl Ester Impurity
Bendamustine Nitro Isopropyl Ester Impurity
  • CAT. No.B040033
  • CAS. No.1374784-01-6
  • Mol. F.C15H19N3O4
  • Mol. W.305.33 g/mol
  • Stock Status:Instock
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Bendamustine dinitro impurity
Bendamustine dinitro impurity
  • CAT. No.B040034
  • CAS. No.2044-88-4
  • Mol. F.C7H7N3O4
  • Mol. W.197.15 g/mol
  • Stock Status:Instock
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Bendamustine Impurity 7
Bendamustine Impurity 7
  • CAT. No.B040035
  • CAS. No.NA
  • Mol. F.C16H21Cl2N3O3
  • Mol. W.374.26 g/mol
  • Stock Status:Under Synthesis
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Bendamustine Amino Isopropyl Ester Impurity
Bendamustine Amino Isopropyl Ester Impurity
  • CAT. No.B040036
  • CAS. No.1313020-26-6
  • Mol. F.C15H21N3O2
  • Mol. W.275.35 g/mol
  • Stock Status:Instock
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Bendamustine Dihydroxy Isopropyl Ester Impurity
Bendamustine Dihydroxy Isopropyl Ester Impurity
  • CAT. No.B040037
  • CAS. No.1313020-24-4
  • Mol. F.C19H29N3O4
  • Mol. W.363.451 g/mol
  • Stock Status:Instock
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Bendamustine Hydrochloride Nitro Acid Impurity
Bendamustine Hydrochloride Nitro Acid Impurity
  • CAT. No.B040038
  • CAS. No.31349-48-1
  • Mol. F.C12H13N3O4
  • Mol. W.263.25g/mol
  • Stock Status:Instock
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Bendamustine Hydrochloride Nitro Ethyl Ester Impurity
Bendamustine Hydrochloride Nitro Ethyl Ester Impurity
  • CAT. No.B040039
  • CAS. No.3543-72-4
  • Mol. F.C14H17N3O4
  • Mol. W.291.30g/mol
  • Stock Status:Instock
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Bendamustine Intermediate(1-Methyl-5-amino-1H-benzimidazole-2-butanoic acid ethyl ester)
Bendamustine Intermediate(1-Methyl-5-amino-1H-benzimidazole-2-butanoic acid ethyl ester)
  • CAT. No.B040040
  • CAS. No.3543-73-5
  • Mol. F.C14H19N3O2
  • Mol. W.261.32 g/mol
  • Stock Status:Custom Synthesis
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Bendamustine Propylene Glycol Ester 2
Bendamustine Propylene Glycol Ester 2
  • CAT. No.B040041
  • CAS. No.1219709-89-3
  • Mol. F.C19H27Cl2N3O3
  • Mol. W.416.34 g/mol
  • Stock Status:Custom Synthesis
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Bendamustine Propylene Glycol Ester 1
Bendamustine Propylene Glycol Ester 1
  • CAT. No.B040042
  • CAS. No.1219709-88-2
  • Mol. F.C19H27Cl2N3O3
  • Mol. W.416.34 g/mol
  • Stock Status:Custom Synthesis
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Isopropyl 3-(5-amino-1-methyl-1H-benzimidazol-2-yl)propanoate
Isopropyl 3-(5-amino-1-methyl-1H-benzimidazol-2-yl)propanoate
  • CAT. No.B040043
  • CAS. No.NA
  • Mol. F.C14H19N3O2
  • Mol. W.261.32 g/mol
  • Stock Status:Custom Synthesis
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N-Desmethyl Bendamustine hydrochloride
N-Desmethyl Bendamustine hydrochloride
  • CAT. No.B040044
  • CAS. No.31349-38-9
  • Mol. F.C15H19Cl2N3O2.HCl
  • Mol. W.380.70 g/mol
  • Stock Status:Custom Synthesis
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Bendamustine Impurity 26
Bendamustine Impurity 26
  • CAT. No.B040046
  • CAS. No.119548-63-9
  • Mol. F.C14H14N6O5
  • Mol. W.346.30 g/mol
  • Stock Status:Custom Synthesis
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Bendamustine Impurity 27
Bendamustine Impurity 27
  • CAT. No.B040047
  • CAS. No.NA
  • Mol. F.C15H18N6O4
  • Mol. W.346.34 g/mol
  • Stock Status:Custom Synthesis
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Bendamustine Impurity 28
Bendamustine Impurity 28
  • CAT. No.B040048
  • CAS. No.NA
  • Mol. F.C14H14N6O4
  • Mol. W.330.30 g/mol
  • Stock Status:Custom Synthesis
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Bendamustine Impurity 29
Bendamustine Impurity 29
  • CAT. No.B040049
  • CAS. No.NA
  • Mol. F.C15H16N6O2
  • Mol. W.312.33 g/mol
  • Stock Status:Custom Synthesis
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Bendamustine N-Methyl
Bendamustine N-Methyl
  • CAT. No.B040050
  • CAS. No.NA
  • Mol. F.C16H23N3O2
  • Mol. W.289.37 g/mol
  • Stock Status:Custom Synthesis
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Methyl 5-amino-1-methyl-1H-benzimidazole-2-butanoate
Methyl 5-amino-1-methyl-1H-benzimidazole-2-butanoate
  • CAT. No.B040051
  • CAS. No.1221157-18-1
  • Mol. F.C13H17N3O2
  • Mol. W.247.29 g/mol
  • Stock Status:Instock
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Bendamustine PEG Ester
Bendamustine PEG Ester
  • CAT. No.B040053
  • CAS. No.NA
  • Mol. F.NA
  • Mol. W.NA
  • Stock Status:Custom Synthesis
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Glutaric Acid-2-methylamino-5-nitromonoanilide
Glutaric Acid-2-methylamino-5-nitromonoanilide
  • CAT. No.B040054
  • CAS. No.91644-13-2
  • Mol. F.C12H15N3O5
  • Mol. W.281.27 g/mol
  • Stock Status:Custom Synthesis
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Bendamustine Dideschloroethyl Acid Impurity
Bendamustine Dideschloroethyl Acid Impurity
  • CAT. No.B040055
  • CAS. No.914626-62-3
  • Mol. F.C12H15N3O2
  • Mol. W.233.27 g/mol
  • Stock Status:Instock
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Bendamustine Impurity 2
Bendamustine Impurity 2
  • CAT. No.B040056
  • CAS. No.109882-31-7
  • Mol. F.C17H25N3O4
  • Mol. W.335.40 g/mol
  • Stock Status:Instock
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isopropyl4-(5-(2-hydroxyethylamino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate
isopropyl4-(5-(2-hydroxyethylamino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate
  • CAT. No.B040057
  • CAS. No.NA
  • Mol. F.C17H25N3O3
  • Mol. W.319.40 g/mol
  • Stock Status:Instock
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isopropyl4-(5-((2-hydroxyethyl)(methyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate
isopropyl4-(5-((2-hydroxyethyl)(methyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate
  • CAT. No.B040058
  • CAS. No.NA
  • Mol. F.C18H27N3O3
  • Mol. W.333.43 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Bendamustine
N-Nitroso Bendamustine
  • CAT. No.B040059
  • CAS. No.NA
  • Mol. F.C14H17ClN4O3
  • Mol. W.324.77 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Bendamustine Impurity
N-Nitroso Bendamustine Impurity
  • CAT. No.B040060
  • CAS. No.NA
  • Mol. F.C14H18Cl2N4O3
  • Mol. W.361.22 g/mol
  • Stock Status:Custom Synthesis
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Bendamustine Ether Hydrochloride Impurity
Bendamustine Ether Hydrochloride Impurity
  • CAT. No.B040061
  • CAS. No.2173004-95-8
  • Mol. F.C16H21N3O3.HCl
  • Mol. W.339.82 g/mol
  • Stock Status:Instock
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Bendamustine Impurity 24
Bendamustine Impurity 24
  • CAT. No.B040062
  • CAS. No.88-26-6
  • Mol. F.C15H24O2
  • Mol. W.236.35 g/mol
  • Stock Status:Custom Synthesis
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Bendamustine Ethyl Ester Impurity Hydrochloride
Bendamustine Ethyl Ester Impurity Hydrochloride
  • CAT. No.B040063
  • CAS. No.NA
  • Mol. F.C18H25Cl2N3O2.HCl
  • Mol. W.422.78 g/mol
  • Stock Status:Instock
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Bendamustine Impurity 6
Bendamustine Impurity 6
  • CAT. No.B040064
  • CAS. No.NA
  • Mol. F.C15H21N3O3
  • Mol. W.291.35 g/mol
  • Stock Status:Instock
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N-Nitroso N-Desmethyl Bendamustine Impurity
N-Nitroso N-Desmethyl Bendamustine Impurity
  • CAT. No.B040066
  • CAS. No.NA
  • Mol. F.C15H18Cl2N4O3
  • Mol. W.373.20 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Bendamustine Impurity 2
N-Nitroso Bendamustine Impurity 2
  • CAT. No.B040067
  • CAS. No.NA
  • Mol. F.C13H14ClN5O4
  • Mol. W.339.73 g/mol
  • Stock Status:Custom Synthesis
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Bendamustine Glucose/Fructose Adduct
Bendamustine Glucose/Fructose Adduct
  • CAT. No.B040068
  • CAS. No.NA
  • Mol. F.C22H31Cl2N3O7
  • Mol. W.520.40 g/mol
  • Stock Status:Custom Synthesis
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Bendamustine Impurity 4
Bendamustine Impurity 4
  • CAT. No.B040069
  • CAS. No.NA
  • Mol. F.C12H13N3O7
  • Mol. W.311.25 g/mol
  • Stock Status:Custom Synthesis
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Bendamustine Impurity 5
Bendamustine Impurity 5
  • CAT. No.B040070
  • CAS. No.NA
  • Mol. F.C13H15N3O7
  • Mol. W.325.27 g/mol
  • Stock Status:Custom Synthesis
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Bendamustine impurity 1
Bendamustine impurity 1
  • CAT. No.B040071
  • CAS. No.NA
  • Mol. F.C17H25N3O3
  • Mol. W.319.40 g/mol
  • Stock Status:Custom Synthesis
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Bendamustine impurity 3
Bendamustine impurity 3
  • CAT. No.B040072
  • CAS. No.NA
  • Mol. F.C21H33N3O5
  • Mol. W.407.50 g/mol
  • Stock Status:Custom Synthesis
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Bendamustine Dimer Impurity 2
Bendamustine Dimer Impurity 2
  • CAT. No.B040073
  • CAS. No.NA
  • Mol. F.C35H50N6O7
  • Mol. W.666.81 g/mol
  • Stock Status:Custom Synthesis
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Isotope Labelled Compounds

Bendamustine-D8 Hydrochloride
Bendamustine-D8 Hydrochloride
  • CAT. No.B040052
  • CAS. No.1185068-23-8
  • Mol. F.C16H14D8Cl3N3O2
  • Mol. W.402.77 g/mol
  • Stock Status:Custom Synthesis
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Budesonide Acid D8
Budesonide Acid D8
  • CAT. No.B040065
  • CAS. No.NA
  • Mol. F.C25H24D8O7
  • Mol. W.452.57 g/mol
  • Stock Status:Custom Synthesis
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