Bempedoic Acid Related Compounds & Impurities

Bempedoic Acid is an ATP citrate lyase inhibitor that reduces hepatic cholesterol synthesis upstream of HMG-CoA reductase, used as adjunct LDL-lowering therapy.

Simson Pharma Limited along with its subsidiary offices Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) is a trusted manufacturer and supplier of high-quality pharmaceutical reference standards, offering a comprehensive portfolio of Bempedoic Acid reference standards, pharmacopeial and non-pharmacopeial Bempedoic Acid impurities, related compounds, related substances, metabolites, stable isotope-labelled compounds, deuterium labelled compounds and nitrosamine (N-NO) reference standards.

These materials support pharmaceutical research and development, product development, ANDA and DMF submissions, quality control (QC), analytical method development and validation, stability studies, impurity identification, and genotoxic impurity assessment.

Our Bempedoic Acid-related reference standards are thoroughly characterized using advanced analytical techniques and are supplied with comprehensive Certificates of Analysis (COA) and supporting analytical data from our USFDA certified, ISO 17025 and ISO 17034 accredited Lab, to meet global regulatory expectations. EP and USP traceable reference standards can also be provided upon request, subject to availability. Simson is also a provider of EP and USP traceable standards. To ensure consistent quality and reliability, our reference standards are periodically re-tested according to established quality management procedures.

Pharmaceutical Reference Standards / Impurity Standards

Bempedoic Acid
3,3-diethyl-2,2,14,14-tetramethyl-8-oxopentadecanedioic acid
Bempedoic Acid Keto Diethyl Ester Impurity
Bempedoic Acid Impurity 2
Bempedoic Acid Dihydroxy Impurity
Di Acid Impurity of Bempedoic Acid
Bempedoic Acid Impurity 11
Bempedoic Acid Impurity 3
Bempedoic Acid Impurity 26
N-[(4-methylphenyl)sulfonylmethyl]formamide
Bempedoic Acid Impurity 14
Dimethyl8-hydroxy-2,2,14,14-tetramethylpentadecanedioate
Bempedoic Acid Impurity 25
Bempedoic Acid Impurity 21
2,14-dimethylpentadecan-8-one
2,2,14-trimethyl-8-oxopentadecanedioic acid
Bempedoic Acid Impurity 29
Bempedoic Acid Impurity 15
Bempedoic Acid Impurity 18
Bempedoic Acid Impurity 17
7-(8,8-dimethyl-9-oxooxonan-2-yl)-2,2-dimethylheptanoic acid
7-bromo-2,2-dimethylheptanoic acid
Bempedoic Acid Impurity 30
7-ethoxy-2,2-dimethylheptanoic acid
8-isocyano-2,2,14,14-tetramethyl-8-tosylpentadecanedioic acid
Ethyl 8-isocyano-2,2-dimethyl-8-[(4-methylphenyl)sulfonyl]octanoate
15-ethoxy-8-isocyano-2,2,14,14-tetramethyl-15-oxo-8-tosylpentadecanoic acid
8-isocyano-15-isopropoxy-2,2,14,14-tetramethyl-15-oxo-8-tosylpentadecanoic acid
15-ethoxy-2,2,14,14-tetramethyl-8,15-dioxopentadecanoic acid
Bempedoic Acid Acetyl Impurity
(Z)-diethyl2,2,14,14-tetramethylpentadec-7-enedioate
Bempedoic Acid Impurity 31
Bempedoic Acid Impurity 22
2,2,14,14-tetramethyl-8-oxopentadecanedioic acid monopiperazine salt
methyl 7-hydroxy-2,2-dimethylheptanoate
Bempedoic Acid Impurity 37
Bempedoic Acid Impurity 42
Bempedoic Acid Impurity 39
Bempedoic Acid Impurity 27
Bempedoic Acid Impurity 46
Bempedoic Acid Impurity 9
Bempedoic Acid Impurity 28
Bempedoic Acid Impurity 34
Bempedoic Acid Impurity 8
Bempedoic Acid Impurity 53
Bempedoic Acid Impurity 1
Bempedoic Acid Impurity 4
Bempedoic Acid Impurity 5
Bempedoic Acid Impurity 7
Bempedoic Acid Dimer Trisodium Salt
Bempedoic Acid Dimer
Bempedoic Acid Impurity 10
Bempedoic Acid Impurity 12

Metabolites

8-Keto Metabolite Of Bempedoic Acid
Bempedoic Acid Impurity 1 Acyl Glucuronide
Bempedoic Acid Acyl Glucuronide

Isotope Labelled Compounds

Bempedoic Acid D5
Bempedoic Acid D4
Bempedoic Acid Impurity D4