Baricitinib Related Compounds & Impurities

Baricitinib is a selective JAK1/JAK2 inhibitor used for rheumatoid arthritis, alopecia areata and, under specific authorisations.

Simson Pharma Limited along with its subsidiary offices Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) is a trusted manufacturer and supplier of high-quality pharmaceutical reference standards, offering a comprehensive portfolio of Baricitinib reference standards, pharmacopeial and non-pharmacopeial Baricitinib impurities, related compounds, related substances, metabolites, stable isotope-labelled compounds, deuterium labelled compounds and nitrosamine (N-NO) reference standards.

These materials support pharmaceutical research and development, product development, ANDA and DMF submissions, quality control (QC), analytical method development and validation, stability studies, impurity identification, and genotoxic impurity assessment.

Our Baricitinib-related reference standards are thoroughly characterized using advanced analytical techniques and are supplied with comprehensive Certificates of Analysis (COA) and supporting analytical data from our USFDA certified, ISO 17025 and ISO 17034 accredited Lab, to meet global regulatory expectations. EP and USP traceable reference standards can also be provided upon request, subject to availability. Simson is also a provider of EP and USP traceable standards. To ensure consistent quality and reliability, our reference standards are periodically re-tested according to established quality management procedures.

Pharmaceutical Reference Standards / Impurity Standards

Baricitinib
Baricitinib
  • CAT. No.B1000000
  • CAS. No.1187594-09-7
  • Mol. F.C16H17N7O2S
  • Mol. W.371.40 g/mol
  • Stock Status:Instock
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(4-(7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)methanol
(4-(7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)methanol
  • CAT. No.B1000001
  • CAS. No.NA
  • Mol. F.C16H23N5O2Si
  • Mol. W.345.47 g/mol
  • Stock Status:Custom Synthesis
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Baricitinib Diamine Impurity
Baricitinib Diamine Impurity
  • CAT. No.B1000002
  • CAS. No.952518-97-7
  • Mol. F.C9H7N5
  • Mol. W.185.19 g/mol
  • Stock Status:Instock
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Ruxolitinib Hydroxy Impurity
Ruxolitinib Hydroxy Impurity
  • CAT. No.B1000004
  • CAS. No.1187595-89-6
  • Mol. F.C17H19N7O3S
  • Mol. W.401.45 g/mol
  • Stock Status:Instock
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Baricitinib Sulfonyl Impurity
Baricitinib Sulfonyl Impurity
  • CAT. No.B1000005
  • CAS. No.1187594-13-3
  • Mol. F.C22H31N7O3SSi
  • Mol. W.501.70 g/mol
  • Stock Status:Custom Synthesis
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Baricitinib impurity A
Baricitinib impurity A
  • CAT. No.B1000006
  • CAS. No.1187595-85-2
  • Mol. F.C7H10N2O2S
  • Mol. W.186.23 g/mol
  • Stock Status:Instock
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Baricitinib impurity C
Baricitinib impurity C
  • CAT. No.B1000007
  • CAS. No.2055723-13-0
  • Mol. F.C21H25N7O4S
  • Mol. W.471.50 g/mol
  • Stock Status:Instock
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Baricitinib Impurity 6
Baricitinib Impurity 6
  • CAT. No.B1000009
  • CAS. No.1627504-43-1
  • Mol. F.C14H13N7.2HCl
  • Mol. W.352.22 g/mol
  • Stock Status:Custom Synthesis
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Baricitinib Impurity IV
Baricitinib Impurity IV
  • CAT. No.B1000010
  • CAS. No.1187594-34-8
  • Mol. F.C17H19N7O2S
  • Mol. W.385.44 g/mol
  • Stock Status:Custom Synthesis
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Baricitinib Impurity VII
Baricitinib Impurity VII
  • CAT. No.B1000011
  • CAS. No.1187594-35-9
  • Mol. F.C18H21N7O2S
  • Mol. W.399.47 g/mol
  • Stock Status:Custom Synthesis
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Baricitinib Impurity 7
Baricitinib Impurity 7
  • CAT. No.B1000012
  • CAS. No.1627504-41-9
  • Mol. F.C19H21N7O2
  • Mol. W.379.42 g/mol
  • Stock Status:Custom Synthesis
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Acetamide Baricitinib Impurity
Acetamide Baricitinib Impurity
  • CAT. No.B1000013
  • CAS. No.2271228-51-2
  • Mol. F.C16H19N7O3S
  • Mol. W.389.43 g/mol
  • Stock Status:Instock
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Baricitinib Acetic Acid Impurity
Baricitinib Acetic Acid Impurity
  • CAT. No.B1000014
  • CAS. No.2271228-52-3
  • Mol. F.C16H18N6O4S
  • Mol. W.390.40 g/mol
  • Stock Status:Custom Synthesis
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Baricitinib Impurity VIII
Baricitinib Impurity VIII
  • CAT. No.B1000015
  • CAS. No.2402776-80-9
  • Mol. F.C17H20N6O4S
  • Mol. W.404.44 g/mol
  • Stock Status:Custom Synthesis
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Baricitinib Impurity V
Baricitinib Impurity V
  • CAT. No.B1000016
  • CAS. No.NA
  • Mol. F.C18H21N7O4S2
  • Mol. W.463.53 g/mol
  • Stock Status:Instock
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Barcitinib Lactone Impurity
Barcitinib Lactone Impurity
  • CAT. No.B1000017
  • CAS. No.2910813-43-1
  • Mol. F.C16H18N6O4S
  • Mol. W.390.42 g/mol
  • Stock Status:Instock
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4-bromopyrazole
4-bromopyrazole
  • CAT. No.B1000018
  • CAS. No.2074-45-8
  • Mol. F.C3H3BrN2
  • Mol. W.146.97 g/mol
  • Stock Status:Custom Synthesis
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6-Amino-5-(2,2-diethoxyethyl)-2-mercaptopyrimidin-4-ol
6-Amino-5-(2,2-diethoxyethyl)-2-mercaptopyrimidin-4-ol
  • CAT. No.B1000019
  • CAS. No.7400-05-7
  • Mol. F.C10H17N3O3S
  • Mol. W.259.33 g/mol
  • Stock Status:Custom Synthesis
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6-Amino-5-(2,2-diethoxyethyl)-4-hydroxypyrimidine
6-Amino-5-(2,2-diethoxyethyl)-4-hydroxypyrimidine
  • CAT. No.B1000020
  • CAS. No.7400-06-8
  • Mol. F.C10H17N3O3
  • Mol. W.227.26 g/mol
  • Stock Status:Custom Synthesis
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Baricitinib Nitroso Impurity
Baricitinib Nitroso Impurity
  • CAT. No.B1000021
  • CAS. No.NA
  • Mol. F.C16H16N8O3S
  • Mol. W.400.40 g/mol
  • Stock Status:Custom Synthesis
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Baricitinib Impurity 23
Baricitinib Impurity 23
  • CAT. No.B1000022
  • CAS. No.1919837-50-5
  • Mol. F.C16H25BN4O4S
  • Mol. W.380.27 g/mol
  • Stock Status:Custom Synthesis
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3-Azetidinylidene acetonitrile
3-Azetidinylidene acetonitrile
  • CAT. No.B1000023
  • CAS. No.1315059-55-2
  • Mol. F.C5H6N2
  • Mol. W.94.12 g/mol
  • Stock Status:Custom Synthesis
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Baricitinib Impurity III
Baricitinib Impurity III
  • CAT. No.B1000024
  • CAS. No.NA
  • Mol. F.C22H20N10O2S
  • Mol. W.488.53 g/mol
  • Stock Status:Custom Synthesis
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Baricitinib Impurity 29
Baricitinib Impurity 29
  • CAT. No.B1000025
  • CAS. No.2402776-84-3
  • Mol. F.C23H27N9O4S2
  • Mol. W.557.65 g/mol
  • Stock Status:Limited Stock
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Baricitinib Impurity 28
Baricitinib Impurity 28
  • CAT. No.B1000026
  • CAS. No.1187595-90-9
  • Mol. F.C22H27N7O4S
  • Mol. W.485.56 g/mol
  • Stock Status:Instock
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Baricitinib Impurity 30
Baricitinib Impurity 30
  • CAT. No.B1000027
  • CAS. No.2102104-37-8
  • Mol. F.C25H31N7O4
  • Mol. W.493.56 g/mol
  • Stock Status:Custom Synthesis
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Baricitinib Impurity 16
Baricitinib Impurity 16
  • CAT. No.B1000028
  • CAS. No.2964606-42-4
  • Mol. F.C15H17N7O4S
  • Mol. W.391.40 g/mol
  • Stock Status:Custom Synthesis
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Baricitinib Impurity 17
Baricitinib Impurity 17
  • CAT. No.B1000029
  • CAS. No.2964606-44-6
  • Mol. F.C15H15N7O2S
  • Mol. W.357.40 g/mol
  • Stock Status:Custom Synthesis
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Baricitinib Impurity 32
Baricitinib Impurity 32
  • CAT. No.B1000030
  • CAS. No.1236033-21-8
  • Mol. F.C11H12ClN3O2
  • Mol. W.253.70 g/mol
  • Stock Status:Custom Synthesis
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Baricitinib Impurity 25
Baricitinib Impurity 25
  • CAT. No.B1000031
  • CAS. No.1146629-75-5
  • Mol. F.C12H14ClN3O2
  • Mol. W.267.70 g/mol
  • Stock Status:Custom Synthesis
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Baricitinib Impurity 37
Baricitinib Impurity 37
  • CAT. No.B1000032
  • CAS. No.NA
  • Mol. F.C17H19N7O3S
  • Mol. W.401.44 g/mol
  • Stock Status:Custom Synthesis
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Baricitinib Impurity 36
Baricitinib Impurity 36
  • CAT. No.B1000033
  • CAS. No.NA
  • Mol. F.C16H23N5O2Si
  • Mol. W.345.47 g/mol
  • Stock Status:Custom Synthesis
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Baricitinib Impurity 38
Baricitinib Impurity 38
  • CAT. No.B1000034
  • CAS. No.NA
  • Mol. F.C13H20ClN3OSi
  • Mol. W.297.86 g/mol
  • Stock Status:Custom Synthesis
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Baricitinib Impurity 4
Baricitinib Impurity 4
  • CAT. No.B1000035
  • CAS. No.NA
  • Mol. F.C15H17N7O3S
  • Mol. W.375.04 g/mol
  • Stock Status:Custom Synthesis
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Baricitinib Impurity 5
Baricitinib Impurity 5
  • CAT. No.B1000036
  • CAS. No.NA
  • Mol. F.C16H19N7O4S
  • Mol. W.405.43 g/mol
  • Stock Status:Custom Synthesis
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Baricitinib Impurity 8
Baricitinib Impurity 8
  • CAT. No.B1000037
  • CAS. No.NA
  • Mol. F.C14H17N7O2S
  • Mol. W.347.04 g/mol
  • Stock Status:Custom Synthesis
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Baricitinib Impurity 9
Baricitinib Impurity 9
  • CAT. No.B1000038
  • CAS. No.NA
  • Mol. F.C16H17N7O5S
  • Mol. W.419.42 g/mol
  • Stock Status:Custom Synthesis
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Baricitinib Impurity 10
Baricitinib Impurity 10
  • CAT. No.B1000039
  • CAS. No.NA
  • Mol. F.C16H19N7O5S
  • Mol. W.421.43 g/mol
  • Stock Status:Custom Synthesis
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Baricitinib Impurity 11
Baricitinib Impurity 11
  • CAT. No.B1000040
  • CAS. No.NA
  • Mol. F.C16H17N7O4S
  • Mol. W.403.42 g/mol
  • Stock Status:Custom Synthesis
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Baricitinib Impurity 12
Baricitinib Impurity 12
  • CAT. No.B1000041
  • CAS. No.NA
  • Mol. F.C16H17N7O4S
  • Mol. W.403.42 g/mol
  • Stock Status:Custom Synthesis
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Baricitinib Impurity 13
Baricitinib Impurity 13
  • CAT. No.B1000042
  • CAS. No.NA
  • Mol. F.C15H17N7O3S
  • Mol. W.375.41 g/mol
  • Stock Status:Custom Synthesis
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Baricitinib Impurity 15
Baricitinib Impurity 15
  • CAT. No.B1000044
  • CAS. No.NA
  • Mol. F.C16H19ClN7O2S
  • Mol. W.408.89 g/mol
  • Stock Status:Custom Synthesis
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Baricitinib Impurity 18
Baricitinib Impurity 18
  • CAT. No.B1000045
  • CAS. No.NA
  • Mol. F.C15H17N7O3S
  • Mol. W.375.41 g/mol
  • Stock Status:Custom Synthesis
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Isotope Labelled Compounds

Baricitinib D5
Baricitinib D5
  • CAT. No.B1000008
  • CAS. No.1564241-79-7
  • Mol. F.C16H12D5N7O2S
  • Mol. W.376.45 g/mol
  • Stock Status:Instock
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