Reference Standards | Research Chemicals | Research Services
Reference Standards | Research Chemicals | Research Services
Nitrosamines and N-nitroso compounds
What are nitrosamines?
What are Nitrosamines,
or more correctly N-nitrosoamines,
refer to any molecule containing the nitroso functional group.
Formation of nitrosamines is carried out
through a simple reaction in the presence of secondary, tertiary, or quaternary
amines with a nitrating agent under acidic reaction conditions. However, it was
concluded that the possibility for nitrosamine impurity content was broader
than simply the concurrent presence of nitrites and amines in the synthesis of
the active pharmaceutical ingredient (API).
Simson is specialized in delivering nitroso
amine impurities with Certificate of analysis along with characterization and
purity. We are equipped with ultra-high performance LC-MS and Triple triple
quadrupole MS Mass Spectrometers for accurate determination of purity.
SimSon Pharma provides synthetic and analytical services for custom synthesis of Drug impurities,peptides,metabolites and nitrososmine impurities from miligram to multi gram level.
